ANAT2341 Lab 1 - Sex Determination: Difference between revisions
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== Introduction == | == Introduction == | ||
Mammalian sex determination is regulated by chromosomes. | Mammalian sex determination is regulated by chromosomes. | ||
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* ''SRY'' encodes a 204 amino acid protein that is a member of the HMG (High mobility group) box class of DNA-binding proteins. Transcription factors bind to specific sites of DNA and regulates the transcription (expression) of other genes. | * ''SRY'' encodes a 204 amino acid protein that is a member of the HMG (High mobility group) box class of DNA-binding proteins. Transcription factors bind to specific sites of DNA and regulates the transcription (expression) of other genes. | ||
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Revision as of 15:13, 27 July 2012
ANAT2341 Lab 1: Introduction | Gametogenesis | Oogenesis | Spermatogenesis | Fertilization | Sex Determination | Online Assessment | ANAT2341 Lab 1 - Quiz |
Introduction
Mammalian sex determination is regulated by chromosomes.
- Females have two X chromosomes. (XX)
- Males have a single X and a small Y. (XY)
- The X and Y chromosome are morphologically and functionally different from each other.
- Evolutionary studies have shown that the Y was once the homologous pair for X.
- It is only in the last 5 years that we have some idea about how these two types of chromosomes may be regulated and genes of importance located upon them.
X chromosome
In females - the main scientific problem was understanding gene dosage, only one copy of X chromosome is needed to be genetically active the other copy is inactivated (More? X Inactivation. About the X Chromosome
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Y chromosome
ANAT2341 Lab 1: Introduction | Gametogenesis | Oogenesis | Spermatogenesis | Fertilization | Sex Determination | Online Assessment | ANAT2341 Lab 1 - Quiz |
Glossary Links
- Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Term Link
Cite this page: Hill, M.A. (2024, April 25) Embryology ANAT2341 Lab 1 - Sex Determination. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/ANAT2341_Lab_1_-_Sex_Determination
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G