2018 Group Project 5
From Embryology
| Projects 2018: 1 Adrenal Medulla | 3 Melanocytes | 4 Cardiac | 5 Dorsal Root Ganglion |
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Dorsal Root Ganglion
- If the page does not allow to copy, we can draw the picture out and reference from where it was taken from.
Introduction
Dorsal Root Ganglion is a cluster of neurone found in the dorsal root of the spinal nerve. The cells found in the ganglion develops from the neural crest migration at about 4 weeks post-conception (pc).
History
Embryonic Origins
Developmental Time Course
Differentiation occurs in the early stages of embryonic development. It consists of two embryonic transitional stages: Gliogenesis and maturation of Schwann cells. Matured Schwann cells further differentiates into myelinating and nonmyelinating types.
Adult Function
- Differentiation process
- When they start to function
Tissue / Organ Structure
Molecular Mechanisms / Factors / Genes
Abnormalities / Abnormal Development
- Environmental factors
- Genetic mutations
- Images of how they look like
Animal Models
Current Research (Labs)
Link on current research for DRG [1]
- Provide link on research lab
Glossary
- Brief, clear and concise
Reference List
- ↑ Sapunar D, Kostic S, Banozic A & Puljak L. (2012). Dorsal root ganglion - a potential new therapeutic target for neuropathic pain. J Pain Res , 5, 31-8. PMID: 22375099 DOI.
- ↑ George L, Dunkel H, Hunnicutt BJ, Filla M, Little C, Lansford R & Lefcort F. (2016). In vivo time-lapse imaging reveals extensive neural crest and endothelial cell interactions during neural crest migration and formation of the dorsal root and sympathetic ganglia. Dev. Biol. , 413, 70-85. PMID: 26988118 DOI.
- ↑ George L, Kasemeier-Kulesa J, Nelson BR, Koyano-Nakagawa N & Lefcort F. (2010). Patterned assembly and neurogenesis in the chick dorsal root ganglion. J. Comp. Neurol. , 518, 405-22. PMID: 20017208 DOI.
- ↑ Ogawa R, Fujita K & Ito K. (2017). Mouse embryonic dorsal root ganglia contain pluripotent stem cells that show features similar to embryonic stem cells and induced pluripotent stem cells. Biol Open , 6, 602-618. PMID: 28373172 DOI.
- ↑ Kasemeier-Kulesa JC, Kulesa PM & Lefcort F. (2005). Imaging neural crest cell dynamics during formation of dorsal root ganglia and sympathetic ganglia. Development , 132, 235-45. PMID: 15590743 DOI.
