2017 Group Project 5: Difference between revisions
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| width="40" |<center>'''Embryonic (weeks 4-5)'''</center> | | width="40" |<center>'''Embryonic (weeks 4-5)'''</center> | ||
| width="65" |<center> | | width="65" |<center> The Embryonic stage is the first stage of lung development. It is identified by the emergence of lung buds in the ventral wall of the foregut; these lung buds will later divide to form lobar divisions. The endoderm is responsible for the epithelium of the lung buds which will later differentiate into specialised respiratory epithelium. The mesoderm is responsible for the mesenchyme surrounding the lung buds. | ||
| width="65" |<center> | </center> | ||
| width="65" |<center> Christian Pander, Karl Ernst von Baer, and Heinrich Rathke were among the first to use a new wave of technology in embryology; involving the use of new staining techniques and improved microscopy. Their findings together identified the presence of primary germ layers (ectoderm, endoderm and mesoderm) and the development of early organs. <ref>Gilbert SF. Developmental Biology. 6th edition. Sunderland (MA): Sinauer Associates; 2000. Comparative Embryology. Available from: https://www.ncbi.nlm.nih.gov/books/NBK9974/</ref></center> | |||
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Revision as of 16:33, 7 September 2017
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Lungs
An introduction to the lungs...
On this page, we will be exploring the development of the lungs through the stages of embryonic growth.
Lung Anatomy
Lung Histology
Developmental origin overview
Brief overview of development of lung
More detailed overview in lung development stages
The Respiratory Zone
The Terminal Bronchioles
Alveolar ducts
Alveoli
The Conducting Zone
The Lung Development Stages
Developmental timeline
Developmental signalling processes
Chemicals involved in the development of lungs. Growth factors that contribute to branching of lungs - SHH and fibroblast growth factor as well as any other hormones or factors that are relevant to lung development
The development of a mammalian lung is a multi-step and highly complex process involving signalling pathways.
The conducting system
Branching of lungs Different types of branching - domain branching, planar bifurcation, trifurcation, orthogonal bifurcation.
The mammalian lung develops through branching morphogenesis.
Alveolus: the functional unit
How the alveoli work. Cell types Maturation and development Lungs become fully developed within the mother, however they do not function until birth.
Current understandings and areas of research
include any relevant articles
Review and research articles
Movies
Animal models
Abnormal development
Premature Birth
Lobar Emphysema
Congenital Diaphragmatic Hernia
Azygos lobe
Meconium Aspiration Syndrome
Newborn Respiratory Distress Syndrome
Surfactant Metabolism
Bronchopulmonary Dysplasia
Lung Agenesis
Cystic Fibrosis
CHAOS (Congenital High Airway Obstruction Syndrome)
CPAM (Congenital Pulmonary Airway Malformation)
Lung Cardiovasculature
Future questions
Glossary
References
- ↑ Gilbert SF. Developmental Biology. 6th edition. Sunderland (MA): Sinauer Associates; 2000. Comparative Embryology. Available from: https://www.ncbi.nlm.nih.gov/books/NBK9974/