2017 Group Project 3
|2017 Student Projects|
- 1 Heart
- 1.1 Introduction
- 1.2 Developmental Origin
- 1.3 Developmental Timeline
- 1.4 Developmental Signalling Processes
- 1.5 Current Research And Findings
- 1.6 Animal Models
- 1.7 Abnormal Development
- 1.8 Future Questions
- 1.9 Glossary of Terms
- 1.10 References
The cardiovascular system is the first system to develop and function in the human embryo, and at week four of prenatal development, the heart begins to beat. At the beginning of stage nine (middle of week three) we see the functional folding of the neural plate and development of the neural tube give rise to the differentiation of the germ layers into products that eventually form the fully functional embryonic heart. Advances in technology, ‘coupled with the use of suitable animal models’ has allowed the evolution of our understanding of embryological cardiac developmental, and allows us to observe how it has stemmed from the more “classical accounts”.
The cardiovascular system is the first system to develop and function in the human embryo. Its normal development is vital for fetal life and any defects occurring in its developmental processes can lead to continental heart abnormalities. Advances in technology, ‘coupled with the use of suitable animal models’ has allowed the evolution of our understanding of embryological cardiac developmental and the mechanism underlying this development. This knowledge assists our understanding of how heart abnormalities arise and the possible treatments to be developed in the future.
Embryonic Developmental Timeline
Historic Developmental Timeline
Developmental Signalling Processes
Heart development is a very complicated and dynamic process that requires a high degree of control and regulation. This control is achieved by different molecular pathways expressed at different stages of heart development.
Transforming growth factor β
Current Research And Findings
Glossary of Terms