2017 Group Project 1: Difference between revisions

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==Anatomy of the Cerebral Cortex==
==Anatomy of the Cerebral Cortex==
( Jess)
You might find this helpful (although you need to request copyright permission):
You might find this helpful (although you need to request copyright permission):
"Difference Between Cerebrum and Cerebral Cortex." DifferenceBetween.Com. August 7, 2012. < http://www.differencebetween.com/difference-between-cerebrum-and-vs-cerebral-cortex/ >
"Difference Between Cerebrum and Cerebral Cortex." DifferenceBetween.Com. August 7, 2012. < http://www.differencebetween.com/difference-between-cerebrum-and-vs-cerebral-cortex/ >

Revision as of 21:31, 23 September 2017

2017 Student Projects 
Student Projects: 1 Cerebral Cortex | 2 Kidney | 3 Heart | 4 Eye | 5 Lung | 6 Cerebellum
Student Page - here is the sample page I demonstrated with in the first labs.I remind all students that you have your own Group Forum on Moodle for your discussions, it is only accessible by members of your group.
Editing Links: Editing Basics | Images | Tables | Referencing | Journal Searches | Copyright | Font Colours | Virtual Slide Permalink | My Preferences | One Page Wiki Card | Printing | Movies | Language Translation | Student Movies | Using OpenOffice | Internet Browsers | Moodle | Navigation/Contribution | Term Link | Short URLs | 2018 Test Student

Cerebral Cortex

Stage 22 image 217.jpg

Mark Hill (talk) 15:59, 14 September 2017 (AEST) Feedback

  • lots of sub-headings, but no actual text.
  • no defined structure to the sequence of sub-headings.
  • no research images related to what is an extensively researched topic.
  • historic background of key research findings, put our understanding today in perspective.
  • Lon list of abnormalities, with no description.

Introduction

( ? Susannah )

What is it?

For concept: https://www.youtube.com/watch?v=dNngOlsLuGI

You might find this helpful (although you need to request copyright permission):

"Difference Between Cerebrum and Cerebral Cortex." DifferenceBetween.Com. August 7, 2012. < http://www.differencebetween.com/difference-between-cerebrum-and-vs-cerebral-cortex/ >

Histology of Cerebral Cortex

https://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0024757/ Z5177691 (talk) 22:37, 23 August 2017 (AEST)

Early Development of the Brain (and Nervous System)

( Eden )

https://embryology.med.unsw.edu.au/embryology/index.php/Neural_-_Cerebrum_Development

.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989000/ https://embryology.med.unsw.edu.au/embryology/index.php/Neural_System_Development

Development of Cerebral Cortex

( Anna )

Terminology

  • Corticogenesis:
  • Zones:
    • Ventricular zone
    • Subventricular zone
    • Cortical Plate
    • Preplate: neural progenitor cells split into 2 regions
      • Marginal zone:
      • Subplate:

Timeline

Nature article: https://www.nature.com/nrn/journal/v9/n2/full/nrn2252.html

  • E10.5-- VZ (ventricular zone) single layer of cells- have feet that attach to cerebral wall and start dividing. Slightly polarized.
  • E11.5--cells begin to differentiate (PP/preplate) into “pioneer” neurons and move upward, laying molecular trail for subsequent differentiating neurons
  • E13.5--VZ cells form secondary progenitor population in SVZ, PP (preplate pioneer) cells split into 2 zones (MZ and SP)
    • MZ and SP cells tell newly differentiated and migrating cells where they are
  • E14.5-17.5-- deep layers populated first and then superficial layers later
    • The neuron senses the layer it is in and stops- condense in CP (cortical plate)

6 Layers

Layers I, II, III, IV, V, VI (see "Cortical Layer Review" Z5177691 (talk) 22:57, 23 August 2017 (AEST)


Cell Types

http://www.ruf.rice.edu/~lngbrain/Sidhya/

  • Radial Glial cells--in developing cerebellum, hippocampus, cortex
    • Migrating neurons glump onto radial glial to migrate- move up these RG cells
    • RG Cells for migrating neurons that extend from VZ to get to the outer part of the cortex.
    • Fibers that neurons use to migrate from VZ to their final destination
    • Allows dividing cells (projector neurons)- to migrate not randomly but radially.
    • Radial Glial Cells can divide as well→ overall process requires a lot of membrane

Cell Signaling

Anatomy of the Cerebral Cortex

( Jess)

You might find this helpful (although you need to request copyright permission): "Difference Between Cerebrum and Cerebral Cortex." DifferenceBetween.Com. August 7, 2012. < http://www.differencebetween.com/difference-between-cerebrum-and-vs-cerebral-cortex/ >

Functions of the Cerebral Cortex

For concept:

https://www.youtube.com/watch?v=n6zQbTT0yoY

Abnormalities

( Zainab - z5093005 )

Structural and Functional Abnormalities associated with Cerebral Cortex Development

DRAFT:

-Brain Development overview

https://www.youtube.com/watch?v=XdN9i_ZWGho

-Cerebral Cortex

https://www.youtube.com/watch?v=mGxomKWfJXs

-Cerebral Cortex Functions

https://www.youtube.com/watch?v=X-m0JDCw6TE


Abnormalities List- Draft:

PubMed Article: [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992410/ Another PubMed article to look at abnormalities

http://www.sciencedirect.com/science/article/pii/S0896627300807497

Corpus Callosum Agenesis

<html5media height="400" width="500">https://www.youtube.com/watch?v=7zOa3LLrHKc</html5media> [1]

Fragile X-Syndrome Rett Syndrome Fetal Alcohol Spectrum Disorder (FASD) Microcephaly Focal cortical dysplasia (FCD) Subcortical band heterotopia Classical (Type I) Lisssencephaly Cobblestone (Type II) lissencephaly

Kallmann Syndrome

Lissencephaly

Hemimegalencephaly

Microlissencephaly

Muscle-Eye-Brain Disease

Periventricular Heterotopia

Polymicrogyria

Schizencephaly

Tuberous Sclerosis

Walker-Warburg

Group Discussion Area (temporary heading)

We are supposed to discuss the project here:

https://moodle.telt.unsw.edu.au/mod/hsuforum/view.php?id=1416354

References

For 1.1:

For 1.2:

For 1.3:

For 1.4:

For 1.5:

For 1.6:

PubMed Searches: Cerebral Cortex Development | Cerebrum Development

BMC Dev Biol Search: Cerebral Cortex Development

Recent papers

<pubmed limit=5>Cerebral+Cortex+Development</pubmed>



  1. ezzo - izzo, d. (2007, August 2). How the Body Works : The Corpus Callosum. Retrieved from https://www.youtube.com/watch?v=7zOa3LLrHKc