2015 Group Project 1: Difference between revisions

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useful publications:
useful publications:


The ethics of creating children with three genetic parents. <ref><pubmed> 23608245</pubmed></ref>
PMID 23608245
PMID 23608245
The ethics of creating children with three genetic parents. <ref><pubmed> 23608245</pubmed></ref>


Three-Parent IVF: Gene Replacement for the Prevention of Inherited Mitochondrial Diseases.<ref><pubmed> 24382342</pubmed></ref>
PMID 24382342
PMID 24382342
Three-Parent IVF: Gene Replacement for the Prevention of Inherited Mitochondrial Diseases.<ref><pubmed> 24382342</pubmed></ref>


Mitochondrial function in the human oocyte and embryo and their role in developmental competence.<ref><pubmed> 20933103 </pubmed></ref>
PMID 20933103
PMID 20933103
Mitochondrial function in the human oocyte and embryo and their role in developmental competence.<ref><pubmed> 20933103 </pubmed></ref>


Mitochondrial reshaping accompanies neural differentiation in the developing spinal cord.<ref><pubmed> 26020522 </pubmed></ref>
PMID 26020522
PMID 26020522
Mitochondrial reshaping accompanies neural differentiation in the developing spinal cord.<ref><pubmed> 26020522 </pubmed></ref>


The impact of mitochondrial function/dysfunction on IVF and new treatment possibilities for infertility.<ref><pubmed> 25421171</pubmed></ref>
PMID 25421171
PMID 25421171
The impact of mitochondrial function/dysfunction on IVF and new treatment possibilities for infertility.<ref><pubmed> 25421171</pubmed></ref>


Risks inherent to mitochondrial replacement.<ref><pubmed> 25807984</pubmed></ref>
PMID 25807984
PMID 25807984
Risks inherent to mitochondrial replacement.<ref><pubmed> 25807984</pubmed></ref>


=Glossary=
=Glossary=

Revision as of 13:19, 23 October 2015

2015 Student Projects 
2015 Projects: Three Person Embryos | Ovarian Hyper-stimulation Syndrome | Polycystic Ovarian Syndrome | Male Infertility | Oncofertility | Preimplantation Genetic Diagnosis | Students
2015 Group Project Topic - Assisted Reproductive Technology
This page is an undergraduate science embryology student and may contain inaccuracies in either description or acknowledgements.

Three Person Embryos

Three Person Embryos are embryos from oocytes that contain maternal and paternal DNA, and mitochondria from a third donor. Collectively, the techniques for the creation of Three Person Embryos are referred to as Mitochondrial Donation or Mitochondrial replacement-assisted IVF. Mitochondrial donation is used for the prevention of maternal inheritance of Mitochondrial disorders that occur due to the mutation of mitochondrial DNA (mtDNA). It is considered a germ-line therapy, with the donated mitochondria being passed maternally to the next generation. Because of this it has generated debate in the media and scientific community over the ethics of its use, since the first techniques were developed in the 1980s. Recently, with the development of safer techniques, the United Kingdom and United States have begun the process of legalizing its clinical use.


<html5media width="560" height="315">https://www.youtube.com/embed/0Zs2KntZ7vU</html5media>

Teenage Girl Has Three Biological Parents [1]

History