2014 Group Project 8

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2014 Student Projects
2014 Student Projects: Group 1 | Group 2 | Group 3 | Group 4 | Group 5 | Group 6 | Group 7 | Group 8
The Group assessment for 2014 will be an online project on Fetal Development of a specific System.

This page is an undergraduate science embryology student and may contain inaccuracies in either description or acknowledgements.

Musculoskeletal

--Mark Hill (talk) 15:21, 26 August 2014 (EST) OK you have nothing here, not even a project title (that I added). I will be asking your group questions in the lab tomorrow. How about some content, references, sources for each section. See Lab 3 Assessment.

General Timeline

Making Gains

For all you big boys out there who want to get jacked this is where it all starts in 2 easy steps. To be expanded upon...THIS IS NOT BROSCIENCE

Muscle development

Mesenchymal progenitor cells from somites(occiptal, cervical, thoracic, lumbar, sacral), undergo multiple differentiation stages to create muscle fibers. The Cranial muscles originate from head mesoderm.


=Background Embryonic development

Second Trimester Muscular development

Third Trimester Muscular development

Muscle fibre types

Abnormalities

References

Anatomy and variations of palmaris longus in fetuses.[1]

Development of the rectus abdominis and its sheath in the human fetus.[2]

Sonic hedgehog acts cell-autonomously on muscle precursor cells to generate limb muscle diversity.[3]

The normal growth of the biceps brachii muscle in human fetuses.[4]

  1. <pubmed> 23529313</pubmed>| [1]
  2. <pubmed> 22869489</pubmed>| [2]
  3. <pubmed> 22987640</pubmed>| [3]
  4. <pubmed>23468258</pubmed>| [4]






Bones and Cartilage development

References

Julie R. Fuchs, Shinichi Terada, Didier Hannouche, Erin R. Ochoa, Joseph P. Vacanti, Dario O. Fauza.Engineered fetal cartilage: Structural and functional analysis in vitro. Journal of Pediatric Surgery Volume 37, Issue 12, Pages 1720–1725, December 2002

Sayer AA1, Cooper C.Fetal programming of body composition and musculoskeletal development.Early Hum Dev. 2005 Sep;81(9):735-44.

Morphometric and ultrasonographic study of the human fetal hip joint during intrauterine development.[1]

Liberty G1, Boldes R, Shen O, Shaul C, Cohen SM, Yagel S. The fetal larynx and pharynx: structure and development on two- and three-dimensional ultrasound. Ultrasound Obstet Gynecol. 2013 Aug;42(2):140-8. doi: 10.1002/uog.12358. Epub 2013 Jul 16.

  1. <pubmed>24398993</pubmed>| [5]

Abnormalities

1 Scoliosis 2. Duchenne Muscular Dystrophy 3. Syndactyly : split-hand malformation

R Geoffrey Burwell, Peter H Dangerfield, Alan Moulton and Theodoros B Grivas. (2011). Adolescent idiopathic scoliosis (AIS), environment, exposome and epigenetics: a molecular perspective of postnatal normal spinal growth and the etiopathogenesis of AIS with consideration of a network . Scoliosis. 6 (6), p1-26

(links: http://www.scoliosisjournal.com/content/6/1/26)

Patrizia Pessina, Daniel Cabrera, María Gabriela Morales, Cecilia A Riquelme, Jaime Gutiérrez, Antonio L Serrano, Enrique Brandan and Pura Muñoz-Cánoves. (2014). Novel and optimized strategies for inducing fibrosis in vivo: focus on Duchenne Muscular Dystrophy. Skeletal Muscle. 4 (7), p1-17

(links: http://www.skeletalmusclejournal.com/content/4/1/7)

Naeimeh Tayebi, Aleksander Jamsheer34, Ricarda Flöttmann1, Anna Sowinska-Seidler, Sandra C Doelken. (2014). Deletions of exons with regulatory activity at the DYNC1I1 locus are associated with split-hand/split-foot malformation: array CGH screening of 134 unrelated families. Orphanet Journal of Rare Disease. 9 (108), p1-9

(links: http://www.ojrd.com/content/9/1/108)

Recent findings

References