2012 Group Project 3

From Embryology

Taste Development

Introduction to the Gustatory System

http://en.wikipedia.org/wiki/Gustatory_system

Timeline of Developmental Processes of the Gustatory System

History of Discoveries

Date Significant Discovery
Date #1 ...
Date #2 ...


Adult Tongue and Taste Buds – Structure and Function

Taste Map

Abnormalities

(try to include technologies to detect abnormalities during pregnancy)

Current Research

In an animal study using mice Suzuki Y, Ikeda K, Kawakami K.(2011) stating that deficiencies in certain Six genes (specifically Six1 & Six4) leads to poor gustatory development. There is also evidence of a cooperative relationship between Six genes for normal development.[1] Another Animal Study involving mice explores a new idea of Neural crest contribution in taste development, specifically the development of papillae and taste buds. Liu HX, Komatsu Y, Mishina Y, Mistretta CM. (2012) suggest that Neural crest cells travel to the location of the tongue in early embryonic stages, gain epithelium phenotypes, multiply and then differentiate to eventually form taste papillae. [2] In an animal study conducted by Rothova M, Thompson H, Lickert H, Tucker AS.(2012) exploring the historically debated issue of endoderm contribution to tongue development showed promising evidence that position of taste buds are patterned by the border of ectoderm and endoderm derivative epithelium. [3]

Future Research

Glossary

References

  1. <pubmed>8955790</pubmed>
  2. <pubmed>9455607</pubmed>
  3. <pubmed>9541477</pubmed>
  4. <pubmed>8241557</pubmed>
  5. <pubmed>22717400</pubmed>

External Links

External Links Notice - The dynamic nature of the internet may mean that some of these listed links may no longer function. If the link no longer works search the web with the link text or name. Links to any external commercial sites are provided for information purposes only and should never be considered an endorsement. UNSW Embryology is provided as an educational resource with no clinical information or commercial affiliation.


--Mark Hill 12:22, 15 August 2012 (EST) Please leave the content listed below the line at the bottom of your project page.


2012 Projects: Vision | Somatosensory | Taste | Olfaction | Abnormal Vision | Hearing