2010 Group Project 5

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Fetal Fibronectin


Fetal Fibronectin

The Fetal Fibronectin (fFN) test measures the amount of secretions of fFN from a woman's vagina and cervix. This technique is used to determine the likelihood of a premature birth occurring. Fetal fibronectin is a protein based plasma that acts as a form of glue attaching the amniotic sac to the uterine wall. Fetal fibronectin is commonly present between 22 to 35 weeks of pregnancy. It is released into the upper vagina towards the onset of labour. If the test finds fFN between this period, the woman will have a chance of going into labour. Hence, if there is no fFN found, it is most likely that they woman will not going into pre-term labour. Therefore, this test allows the woman to see if they are at risk or not.

About pre-term births

History of Fetal Fibronectin


Test Results


The FFN remains relatively very low levels throughout the first 22 weeks of gestation.The following dramatically increase of the concentration that reaches 50 ng/mL or over from 22nd week onwards associates with the increase of the incidence of preterm labor before week 37th of gastation.<ref><pubmed>20734676</pubmed></ref>


Further Research



2010 ANAT2341 Group Projects

Project 1 - Ultrasound | Project 2 - Chorionic villus sampling | Project 3 - Amniocentesis | Group Project 4 - Percutaneous Umbilical Cord Blood Sampling | Project 5 - Fetal Fibronectin | Project 6 - Maternal serum alpha-fetoprotein | Group Assessment Criteria

Glossary Links

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Cite this page: Hill, M.A. (2021, July 27) Embryology 2010 Group Project 5. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/2010_Group_Project_5

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© Dr Mark Hill 2021, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G