2010 BGD Practical - Fertilization to Implantation

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Introduction

We will study human development over a series of 3 practical classes spanning the overall human prenatal developmental timecourse. There will be an additional class covering the extramebryonic tissues formed from the conceptus (the embryonic membranes and placenta).


Online Practical Help

  1. Online Practical Pages contain movies which work better using the Firefox browser on your desktop (Internet Explorer may crash)
  2. Bookmark this current page (so you don't get lost)
  3. Work through the series of linked online resources with the demonstrator (listed in order the lefthand menu on each page)
  4. Online Page Organisation is the same on each page with a lefthand menu and righthand content (here)
  5. Page Content has a series of images, text and movies down the page in sequence, a list of Terms and a link to a Glossary (near the bottom of each page is a link "the white rabbit" to the next page)
  6. External Links there are links on some pages which may take you to other places outside the current Practical (navigate carefully, remember point 2!)
  7. Finished when we have reached and discussed Week 3 Overview (pages Medicine, Histology and References are not covered in the Practical but for your own additional study)

Practical - Fertilization to Implantation

Aim: This laboratory is an introduction to the earliest event in development, from fertilization of the ovum (egg) by sperm through to implantation.

Key Concepts: Gonad, gametogenesis, ovary, testes, menstral cycle, oocyte development (oogenesis), sperm development (spermatogenesis), sperm morphology/motility, meiosis/mitosis, follicle, ovulation, zona pellucida, polar bodies, hormonal changes, mechanism of fertilization, post-fertilization changes, corpus luteum, zygote, morula, blastocyst, zona pellucida, embryoblast, trophoblast, ectopic implantation, abnormalities.

Key Reading:

  • Human Embryology, WJ. Larsen Chapter 1, 2, 3
  • The Developing Human: Clinically Oriented Embryology. Moore & Persaud Chapter 1, 2