https://embryology.med.unsw.edu.au/embryology/index.php?action=history&feed=atom&title=Talk%3ADevelopmental_Mechanism_-_TimeTalk:Developmental Mechanism - Time - Revision history2026-10-29T12:28:21ZRevision history for this page on the wikiMediaWiki 1.39.10https://embryology.med.unsw.edu.au/embryology/index.php?title=Talk:Developmental_Mechanism_-_Time&diff=355353&oldid=prevZ8600021: Created page with "{{Talk Page}} ==2017== J Exp Zool B Mol Dev Evol. 2017 Jan;328(1-2):157-164. doi: 10.1002/jez.b.22698. Epub 2016 Sep 23. Heterochrony and Morphological Variation of Epithala..."2018-10-04T03:23:42Z<p>Created page with "{{Talk Page}} ==2017== J Exp Zool B Mol Dev Evol. 2017 Jan;328(1-2):157-164. doi: 10.1002/jez.b.22698. Epub 2016 Sep 23. Heterochrony and Morphological Variation of Epithala..."</p>
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==2017==<br />
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J Exp Zool B Mol Dev Evol. 2017 Jan;328(1-2):157-164. doi: 10.1002/jez.b.22698. Epub 2016 Sep 23.<br />
Heterochrony and Morphological Variation of Epithalamic Asymmetry.<br />
Signore IA1,2, Concha ML1,3.<br />
Author information<br />
Abstract<br />
Heterochrony is one proposed mechanism to explain how morphological variation and novelty arise during evolution. To experimentally approach heterochrony in a comprehensive manner, we must consider all three aspects of developmental time (sequence, timing, duration). This task is only possible in developmental models that allow the acquisition of high-quality temporal data in the context of normalized developmental time. Here we propose that epithalamic asymmetry of teleosts is one such model. Comparative studies among related teleost species have revealed heterochronic shifts in the timing of ontogenic events leading to the development of epithalamic asymmetry. Such temporal changes involve neural structures critical for tissue-tissue interactions underlying the generation of asymmetry and are concurrent with the appearance of morphological differences in the pattern of asymmetry between species. Based on these findings, we hypothesize that interspecies variation of epithalamic asymmetry results from changes in the timing of tissue-tissue interactions critical for the establishment of asymmetry during ontogeny. Importantly, this hypothesis can be tested by systematic comparative approaches among teleosts species based on normalized developmental time, combined with experimental manipulation of epithalamic asymmetry development.<br />
PMID: 27659033 DOI: 10.1002/jez.b.22698</div>Z8600021