Oocyte Development - Revision history

Z8600021 at 00:55, 6 April 2020

2020-04-06T00:55:44Z

← Older revision		Revision as of 10:55, 6 April 2020
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	! [[Embryology_History\|'''Historic Embryology''']] - Oocyte		! [[Embryology_History\|'''Historic Embryology''']] - Oocyte
	\|-		\|-
	\| [[Paper - History of the development of the human ovum (1834)\|1834 Human and other species Ovum]] \| [[Paper - The Maturation of the Human Ovum\|1919 Human Ovum]] \| [[Book_-_Text-Book_of_Embryology_1#The_Ovum\|1921 The Ovum]] \| [[Paper - The fate of the graafian follicle in the human ovary\|1925 Human Graafian Follicle]] \| [[Paper - Human oocyte showing first polar body and metaphase stage in formation of second polar body\|1927 Second polar body]] \| [[Paper - How Large is the Mammalian Egg?\|1929 Oocyte Size]] \| [[Paper - Human ova from large follicles\|1930 Human large follicles]] \| [[Paper - Studies on the human oocyte and its follicle 1\|1967 Oocyte EM]] \| [[Paper - Cell-to-cell communication and ovulation - A study of the cumulus-oocyte complex\|1978 Cumulus-oocyte complex]]		\| [[Paper - History of the development of the human ovum (1834)\|1834 Human and other species Ovum]] \| [[Paper - The Maturation of the Human Ovum\|1919 Human Ovum]] \| [[Book_-_Text-Book_of_Embryology_1#The_Ovum\|1921 The Ovum]] \| [[Paper - The fate of the graafian follicle in the human ovary\|1925 Human Graafian Follicle]] \| [[Paper - Human oocyte showing first polar body and metaphase stage in formation of second polar body\|1927 Second polar body]] \| [[Paper - How Large is the Mammalian Egg?\|1929 Oocyte Size]] \| [[Paper - Human ova from large follicles - including a search for maturation divisions and observations on atresia (1930)\|1930 Human large follicles]] \| [[Paper - Studies on the human oocyte and its follicle 1\|1967 Oocyte EM]] \| [[Paper - Cell-to-cell communication and ovulation - A study of the cumulus-oocyte complex\|1978 Cumulus-oocyte complex]]
	\|}		\|}
	{{Genital Links}}		{{Genital Links}}

Z8600021 at 01:13, 12 February 2020

2020-02-12T01:13:33Z

← Older revision		Revision as of 11:13, 12 February 2020
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	{{Fertilization Links}}		{{Fertilization Links}}
	~~<br>~~
	{\| class="wikitable mw-collapsible mw-collapsed"		{\| class="wikitable mw-collapsible mw-collapsed"
	! [[Embryology_History\|'''Historic Embryology''']] - Oocyte		! [[Embryology_History\|'''Historic Embryology''']] - Oocyte
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	\| [[Paper - History of the development of the human ovum (1834)\|1834 Human and other species Ovum]] \| [[Paper - The Maturation of the Human Ovum\|1919 Human Ovum]] \| [[Book_-_Text-Book_of_Embryology_1#The_Ovum\|1921 The Ovum]] \| [[Paper - The fate of the graafian follicle in the human ovary\|1925 Human Graafian Follicle]] \| [[Paper - Human oocyte showing first polar body and metaphase stage in formation of second polar body\|1927 Second polar body]] \| [[Paper - How Large is the Mammalian Egg?\|1929 Oocyte Size]] \| [[Paper - Human ova from large follicles\|1930 Human large follicles]] \| [[Paper - Studies on the human oocyte and its follicle 1\|1967 Oocyte EM]] \| [[Paper - Cell-to-cell communication and ovulation - A study of the cumulus-oocyte complex\|1978 Cumulus-oocyte complex]]		\| [[Paper - History of the development of the human ovum (1834)\|1834 Human and other species Ovum]] \| [[Paper - The Maturation of the Human Ovum\|1919 Human Ovum]] \| [[Book_-_Text-Book_of_Embryology_1#The_Ovum\|1921 The Ovum]] \| [[Paper - The fate of the graafian follicle in the human ovary\|1925 Human Graafian Follicle]] \| [[Paper - Human oocyte showing first polar body and metaphase stage in formation of second polar body\|1927 Second polar body]] \| [[Paper - How Large is the Mammalian Egg?\|1929 Oocyte Size]] \| [[Paper - Human ova from large follicles\|1930 Human large follicles]] \| [[Paper - Studies on the human oocyte and its follicle 1\|1967 Oocyte EM]] \| [[Paper - Cell-to-cell communication and ovulation - A study of the cumulus-oocyte complex\|1978 Cumulus-oocyte complex]]
	\|}		\|}
	~~<br>~~
	{{Genital Links}}		{{Genital Links}}
	== Some Recent Findings ==		== Some Recent Findings ==

Z8600021 at 03:00, 11 December 2019

2019-12-11T03:00:04Z

← Older revision		Revision as of 13:00, 11 December 2019
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	! [[Embryology_History\|'''Historic Embryology''']] - Oocyte		! [[Embryology_History\|'''Historic Embryology''']] - Oocyte
	\|-		\|-
	\| [[Paper - The Maturation of the Human Ovum\|1919 Human Ovum]] \| [[Book_-_Text-Book_of_Embryology_1#The_Ovum\|1921 The Ovum]] \| [[Paper - The fate of the graafian follicle in the human ovary\|1925 Human Graafian Follicle]] \| [[Paper - Human oocyte showing first polar body and metaphase stage in formation of second polar body\|1927 Second polar body]] \| [[Paper - How Large is the Mammalian Egg?\|1929 Oocyte Size]] \| [[Paper - Human ova from large follicles\|1930 Human large follicles]] \| [[Paper - Studies on the human oocyte and its follicle 1\|1967 Oocyte EM]] \| [[Paper - Cell-to-cell communication and ovulation - A study of the cumulus-oocyte complex\|1978 Cumulus-oocyte complex]]		\| [[Paper - History of the development of the human ovum (1834)\|1834 Human and other species Ovum]] \| [[Paper - The Maturation of the Human Ovum\|1919 Human Ovum]] \| [[Book_-_Text-Book_of_Embryology_1#The_Ovum\|1921 The Ovum]] \| [[Paper - The fate of the graafian follicle in the human ovary\|1925 Human Graafian Follicle]] \| [[Paper - Human oocyte showing first polar body and metaphase stage in formation of second polar body\|1927 Second polar body]] \| [[Paper - How Large is the Mammalian Egg?\|1929 Oocyte Size]] \| [[Paper - Human ova from large follicles\|1930 Human large follicles]] \| [[Paper - Studies on the human oocyte and its follicle 1\|1967 Oocyte EM]] \| [[Paper - Cell-to-cell communication and ovulation - A study of the cumulus-oocyte complex\|1978 Cumulus-oocyte complex]]
	\|}		\|}
	<br>		<br>

Z8600021 at 03:50, 27 March 2019

2019-03-27T03:50:50Z

← Older revision		Revision as of 13:50, 27 March 2019
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	! [[Embryology_History\|'''Historic Embryology''']] - Oocyte		! [[Embryology_History\|'''Historic Embryology''']] - Oocyte
	\|-		\|-
	\| [[Paper - The Maturation of the Human Ovum\|1919 Human Ovum]] \| [[Book_-_Text-Book_of_Embryology_1#The_Ovum\|1921 The Ovum]] \| [[Paper - How Large is the Mammalian Egg?\|1929 Oocyte Size]]		\| [[Paper - The Maturation of the Human Ovum\|1919 Human Ovum]] \| [[Book_-_Text-Book_of_Embryology_1#The_Ovum\|1921 The Ovum]] \| [[Paper - The fate of the graafian follicle in the human ovary\|1925 Human Graafian Follicle]] \| [[Paper - Human oocyte showing first polar body and metaphase stage in formation of second polar body\|1927 Second polar body]] \| [[Paper - How Large is the Mammalian Egg?\|1929 Oocyte Size]] \| [[Paper - Human ova from large follicles\|1930 Human large follicles]] \| [[Paper - Studies on the human oocyte and its follicle 1\|1967 Oocyte EM]] \| [[Paper - Cell-to-cell communication and ovulation - A study of the cumulus-oocyte complex\|1978 Cumulus-oocyte complex]]
	\|}		\|}
	<br>		<br>

Z8600021 at 03:40, 27 March 2019

2019-03-27T03:40:39Z

← Older revision		Revision as of 13:40, 27 March 2019
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	{{Fertilization Links}}		{{Fertilization Links}}
	<br>		<br>
	~~{{Genital Links}}~~

	{\| class="wikitable mw-collapsible mw-collapsed"		{\| class="wikitable mw-collapsible mw-collapsed"
	! [[Embryology_History\|'''Historic Embryology''']] - Oocyte		! [[Embryology_History\|'''Historic Embryology''']] - Oocyte
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	\| [[Paper - The Maturation of the Human Ovum\|1919 Human Ovum]] \| [[Book_-_Text-Book_of_Embryology_1#The_Ovum\|1921 The Ovum]] \| [[Paper - How Large is the Mammalian Egg?\|1929 Oocyte Size]]		\| [[Paper - The Maturation of the Human Ovum\|1919 Human Ovum]] \| [[Book_-_Text-Book_of_Embryology_1#The_Ovum\|1921 The Ovum]] \| [[Paper - How Large is the Mammalian Egg?\|1929 Oocyte Size]]
	\|}		\|}
			<br>
			{{Genital Links}}
	== Some Recent Findings ==		== Some Recent Findings ==
	{\|		{\|

Z8600021 at 03:39, 27 March 2019

2019-03-27T03:39:52Z

← Older revision		Revision as of 13:39, 27 March 2019
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	:''In an adult human female, the development of a primordial follicle containing an oocyte to a preovulatory follicle takes in excess of 120 days.''		:''In an adult human female, the development of a primordial follicle containing an oocyte to a preovulatory follicle takes in excess of 120 days.''

			{{Fertilization Links}}
			<br>
	{{Genital Links}}		{{Genital Links}}

Z8600021 at 03:37, 27 March 2019

2019-03-27T03:37:43Z

← Older revision		Revision as of 13:37, 27 March 2019
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	\| [[File:Human pronuclear stage EM26.jpg\|300px]]		\| [[File:Human pronuclear stage EM26.jpg\|300px]]
	\| [[File:Human pronuclear stage EM29.jpg\|300px]]		\| [[File:Human pronuclear stage EM29.jpg\|300px]]
			\|-
	\| First polar body (PB1) portion of the cytoplasm. Few mitochondria, large ER vesicles are collapsed, absence of the small ER vesicles. Numerous dense cortical granules (eg) are present beneath the plasma membrane of the polar body. X 24,000		\| First polar body (PB1) portion of the cytoplasm. Few mitochondria, large ER vesicles are collapsed, absence of the small ER vesicles. Numerous dense cortical granules (eg) are present beneath the plasma membrane of the polar body. X 24,000
	\| Second polar body (PB2) spheroidal nucleus consisting of dense chromatin aggregates and a highly hydrated nucleoplasm. A double nuclear membrane is present. X 15,000		\| Second polar body (PB2) spheroidal nucleus consisting of dense chromatin aggregates and a highly hydrated nucleoplasm. A double nuclear membrane is present. X 15,000

Z8600021 at 03:36, 27 March 2019

2019-03-27T03:36:41Z

← Older revision		Revision as of 13:36, 27 March 2019
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	{\|		{\|
	\|+ '''Polar Body (Electron Micrograph)'''		\|+ '''Polar Body (Electron Micrograph)'''{{#pmid:6008199\|PMID6008199}}
	\|-		\|-
	! First Polar Body		! First Polar Body

Z8600021 at 03:35, 27 March 2019

2019-03-27T03:35:44Z

← Older revision		Revision as of 13:35, 27 March 2019
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	{\|		{\|
	\|+ Polar Body (EM)		\|+ '''Polar Body (Electron Micrograph)'''
	\|-		\|-
	! First Polar Body		! First Polar Body
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	\| [[File:Human pronuclear stage EM26.jpg\|300px]]		\| [[File:Human pronuclear stage EM26.jpg\|300px]]
	\| [[File:Human pronuclear stage EM29.jpg\|300px]]		\| [[File:Human pronuclear stage EM29.jpg\|300px]]
			\| First polar body (PB1) portion of the cytoplasm. Few mitochondria, large ER vesicles are collapsed, absence of the small ER vesicles. Numerous dense cortical granules (eg) are present beneath the plasma membrane of the polar body. X 24,000
			\| Second polar body (PB2) spheroidal nucleus consisting of dense chromatin aggregates and a highly hydrated nucleoplasm. A double nuclear membrane is present. X 15,000
	\|}		\|}

Z8600021 at 03:32, 27 March 2019

2019-03-27T03:32:18Z

← Older revision		Revision as of 13:32, 27 March 2019
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	[[File:Frazer002_bw600.jpg\|thumb\|alt=Historic drawing comparing the size of the mature human oocyte with a spermatozoa\|Historic drawing comparing the size of the mature human oocyte with a spermatozoa]]		[[File:Frazer002_bw600.jpg\|thumb\|alt=Historic drawing comparing the size of the mature human oocyte with a spermatozoa\|Historic drawing comparing the size of the mature human oocyte with a spermatozoa]]

	The {{oocyte}} (eggs, ova) is arrested at an early stage of the first {{meiosis))(first meiotic) division as a primary oocyte (primordial follicle) within the {{ovary}}. Following puberty, during each menstrual cycle, pituitary gonadotrophin stimulates completion of meiosis 1 the day before ovulation. Early oocytes are also classified as immature (germinal vesicle (GV) or metaphase I (MI) stage). The breakdown of the germinal vesicle indicates a resumption of meiosis and the extrusion of the first polar body (1 PB) indicates completion of the first meiotic division in human oocytes.		The {{oocyte}} (eggs, ova, ovum) is arrested at an early stage of the first {{meiosis))(first meiotic) division as a primary oocyte (primordial follicle) within the {{ovary}}. Following puberty, during each menstrual cycle, pituitary gonadotrophin stimulates completion of meiosis 1 the day before ovulation. Early oocytes are also classified as immature (germinal vesicle (GV) or metaphase I (MI) stage). The breakdown of the germinal vesicle indicates a resumption of meiosis and the extrusion of the first {{polar body}} (1 PB) indicates completion of the first meiotic division in human oocytes.

	The released oocyte is surrounded by a thick specialised extracellular matrix, the {{zona pellucida}}, that in turn is covered in layers of cells, the [[granulosa cell\|granulosa layer]].		The released oocyte is surrounded by a thick specialised extracellular matrix, the {{zona pellucida}}, that in turn is covered in layers of cells, the [[granulosa cell\|granulosa layer]].
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	Recent research in some species suggest that the space formed by the peripheral polar body (between the oocyte and the zona pellucia) can influence the site of spermatozoa fertilization.		Recent research in some species suggest that the space formed by the peripheral polar body (between the oocyte and the zona pellucia) can influence the site of spermatozoa fertilization.

	~~<gallery caption="~~Polar Body (EM)">		{\|
	~~File:Human pronuclear stage EM26.jpg~~\|First Polar Body		\|+ Polar Body (EM)
	~~File:Human pronuclear stage EM27.jpg\|First~~ Polar Body		\|-
	File:Human pronuclear stage ~~EM28~~.jpg\|~~First Polar Body~~		! First Polar Body
	File:Human pronuclear stage EM29.jpg\|~~Second Polar Body~~		! Second Polar Body
	~~File:Human pronuclear stage EM30.jpg~~\|~~Second Polar Body~~		\|-
	~~</gallery>~~		\| [[File:Human pronuclear stage EM26.jpg\|300px]]
			\| [[File:Human pronuclear stage EM29.jpg\|300px]]
			\|}

	===Polar Body Extrusion Model===		===Polar Body Extrusion Model===