Neural Crest - Schwann Cell Development - Revision history

Z8600021 at 00:21, 5 February 2020

2020-02-05T00:21:57Z

← Older revision		Revision as of 11:21, 5 February 2020
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	==Introduction==		==Introduction==
	{\|		{\|
	\| Schwann cells are glial cells that originate and development from {{neural crest}} cells migrating out along the developing nerve fibers. These cells differentiate to wrap around nerve axon processes to form myelin sheaths that improve nerve conduction. This process of myelination occurs also within the central nervous system by another population of glial cells~~, the oligodendrocytes~~. (More? {{gliogenesis}})		\| Schwann cells are glial cells that originate and development from {{neural crest}} cells migrating out along the developing nerve fibers. These cells differentiate to wrap around nerve axon processes to form myelin sheaths that improve nerve conduction. This process of myelination occurs also within the central nervous system by another population of glial cells. (More? {{gliogenesis}})

	<br>		<br>
	\| [[File:Myelination animation.gif]]		\| [[File:Myelination animation.gif]]
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	Myelination		Myelination
	\|}		\|}
	{\|		<br>
	~~\|+ Historic Embryology~~		{{Schwann Cell Vignette}}
	~~\|-bgcolor="FAF5FF"~~
	~~\| width=65px\|[[File:Theodor~~ Schwann~~.jpg\|60px]]~~
	~~\| Schwann cells are named after Theodor Schwann (1810 - 1882) a German physiologist.~~
	\|}
	<br>		<br>
	{{Glia Links}}		{{Glia Links}}

	<br>		<br>
	{{Neural Crest Links}}		{{Neural Crest Links}}
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	\|-bgcolor="F5FAFF"		\|-bgcolor="F5FAFF"
	\|		\|
	* '''DNA methylation in {{Schwann cell}}s and in {{oligodendrocyte}}s'''{{#pmid:31958184}} "DNA methylation is one of many {{epigenetics}} marks, which directly modifies base residues, usually cytosines, in a multiple-step cycle. It has been linked to the regulation of gene expression and alternative splicing in several cell types, including during cell lineage specification and differentiation processes. DNA methylation changes have also been observed during aging, and aberrant methylation patterns have been reported in several neurological diseases. We here review the role of DNA methylation in {{Schwann cell}}s and {{oligodendrocyte}}s, the myelin-forming glia of the peripheral and central nervous systems, respectively. We first address how methylation and demethylation are regulating myelinating cells' differentiation during development and repair. We then mention how DNA methylation dysregulation in diseases and cancers could explain their pathogenesis by directly influencing myelinating cells' proliferation and differentiation capacities."

	* '''Dual origin of enteric neurons in vagal Schwann cell precursors and the sympathetic neural crest'''{{#pmid:29078343\|PMID29078343}} "Most of the enteric nervous system derives from the "vagal" neural crest, lying at the level of somites 1-7, which invades the digestive tract rostro-caudally from the foregut to the hindgut. Little is known about the initial phase of this colonization, which brings enteric precursors into the foregut. Here we show that the "vagal crest" subsumes two populations of enteric precursors with contrasted origins, initial modes of migration, and destinations. Crest cells adjacent to somites 1 and 2 produce Schwann cell precursors that colonize the vagus nerve, which in turn guides them into the esophagus and stomach. Crest cells adjacent to somites 3-7 belong to the crest streams contributing to sympathetic chains: they migrate ventrally, seed the sympathetic chains, and colonize the entire digestive tract thence. Accordingly, enteric ganglia, like sympathetic ones, are atrophic when deprived of signaling through the tyrosine kinase receptor ErbB3, while half of the esophageal ganglia require, like parasympathetic ones, the nerve-associated form of the ErbB3 ligand, Neuregulin-1. These dependencies might bear relevance to Hirschsprung disease, with which alleles of Neuregulin-1 are associated."		* '''Dual origin of enteric neurons in vagal Schwann cell precursors and the sympathetic neural crest'''{{#pmid:29078343\|PMID29078343}} "Most of the enteric nervous system derives from the "vagal" neural crest, lying at the level of somites 1-7, which invades the digestive tract rostro-caudally from the foregut to the hindgut. Little is known about the initial phase of this colonization, which brings enteric precursors into the foregut. Here we show that the "vagal crest" subsumes two populations of enteric precursors with contrasted origins, initial modes of migration, and destinations. Crest cells adjacent to somites 1 and 2 produce Schwann cell precursors that colonize the vagus nerve, which in turn guides them into the esophagus and stomach. Crest cells adjacent to somites 3-7 belong to the crest streams contributing to sympathetic chains: they migrate ventrally, seed the sympathetic chains, and colonize the entire digestive tract thence. Accordingly, enteric ganglia, like sympathetic ones, are atrophic when deprived of signaling through the tyrosine kinase receptor ErbB3, while half of the esophageal ganglia require, like parasympathetic ones, the nerve-associated form of the ErbB3 ligand, Neuregulin-1. These dependencies might bear relevance to Hirschsprung disease, with which alleles of Neuregulin-1 are associated."

			* '''How Schwann Cells Sort Axons: New Concepts'''{{#pmid:25686621\|PMID25686621}} "Peripheral nerves contain large myelinated and small unmyelinated (Remak) fibers that perform different functions. The choice to myelinate or not is dictated to Schwann cells by the axon itself, based on the amount of neuregulin I-type III exposed on its membrane. Peripheral axons are more important in determining the final myelination fate than central axons, and the implications for this difference in Schwann cells and oligodendrocytes are discussed. Interestingly, this choice is reversible during pathology, accounting for the remarkable plasticity of Schwann cells, and contributing to the regenerative potential of the peripheral nervous system. Radial sorting is the process by which Schwann cells choose larger axons to myelinate during development."
	\|}		\|}
	{\| class="wikitable mw-collapsible mw-collapsed"		{\| class="wikitable mw-collapsible mw-collapsed"
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	\|-		\|-
	\| {{Older papers}}		\| {{Older papers}}
	* '''How Schwann Cells Sort Axons: New Concepts'''{{#pmid:25686621\|PMID25686621}} "Peripheral nerves contain large myelinated and small unmyelinated (Remak) fibers that perform different functions. The choice to myelinate or not is dictated to Schwann cells by the axon itself, based on the amount of neuregulin I-type III exposed on its membrane. Peripheral axons are more important in determining the final myelination fate than central axons, and the implications for this difference in Schwann cells and oligodendrocytes are discussed. Interestingly, this choice is reversible during pathology, accounting for the remarkable plasticity of Schwann cells, and contributing to the regenerative potential of the peripheral nervous system. Radial sorting is the process by which Schwann cells choose larger axons to myelinate during development."

	* '''Neural crest origin of olfactory ensheathing glia'''{{#pmid:21078992\|PMID21078992}} "Olfactory ensheathing cells (OECs) are a unique class of glial cells with exceptional translational potential because of their ability to support axon regeneration in the central nervous system. Although OECs are similar in many ways to immature and nonmyelinating Schwann cells, and can myelinate large-diameter axons indistinguishably from myelination by Schwann cells, current dogma holds that OECs arise from the olfactory epithelium. Here, using fate-mapping techniques in chicken embryos and genetic lineage tracing in mice, we show that OECs in fact originate from the neural crest and hence share a common developmental heritage with Schwann cells."		* '''Neural crest origin of olfactory ensheathing glia'''{{#pmid:21078992\|PMID21078992}} "Olfactory ensheathing cells (OECs) are a unique class of glial cells with exceptional translational potential because of their ability to support axon regeneration in the central nervous system. Although OECs are similar in many ways to immature and nonmyelinating Schwann cells, and can myelinate large-diameter axons indistinguishably from myelination by Schwann cells, current dogma holds that OECs arise from the olfactory epithelium. Here, using fate-mapping techniques in chicken embryos and genetic lineage tracing in mice, we show that OECs in fact originate from the neural crest and hence share a common developmental heritage with Schwann cells."

Z8600021 at 00:09, 5 February 2020

2020-02-05T00:09:49Z

← Older revision		Revision as of 11:09, 5 February 2020
Line 3:		Line 3:
	{\|		{\|
	\| Schwann cells are glial cells that originate and development from {{neural crest}} cells migrating out along the developing nerve fibers. These cells differentiate to wrap around nerve axon processes to form myelin sheaths that improve nerve conduction. This process of myelination occurs also within the central nervous system by another population of glial cells, the oligodendrocytes. (More? {{gliogenesis}})		\| Schwann cells are glial cells that originate and development from {{neural crest}} cells migrating out along the developing nerve fibers. These cells differentiate to wrap around nerve axon processes to form myelin sheaths that improve nerve conduction. This process of myelination occurs also within the central nervous system by another population of glial cells, the oligodendrocytes. (More? {{gliogenesis}})

	<br>		<br>
	\| [[File:Myelination animation.gif]]		\| [[File:Myelination animation.gif]]
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	\|-bgcolor="F5FAFF"		\|-bgcolor="F5FAFF"
	\|		\|
			* '''DNA methylation in {{Schwann cell}}s and in {{oligodendrocyte}}s'''{{#pmid:31958184}} "DNA methylation is one of many {{epigenetics}} marks, which directly modifies base residues, usually cytosines, in a multiple-step cycle. It has been linked to the regulation of gene expression and alternative splicing in several cell types, including during cell lineage specification and differentiation processes. DNA methylation changes have also been observed during aging, and aberrant methylation patterns have been reported in several neurological diseases. We here review the role of DNA methylation in {{Schwann cell}}s and {{oligodendrocyte}}s, the myelin-forming glia of the peripheral and central nervous systems, respectively. We first address how methylation and demethylation are regulating myelinating cells' differentiation during development and repair. We then mention how DNA methylation dysregulation in diseases and cancers could explain their pathogenesis by directly influencing myelinating cells' proliferation and differentiation capacities."

	* '''Dual origin of enteric neurons in vagal Schwann cell precursors and the sympathetic neural crest'''{{#pmid:29078343\|PMID29078343}} "Most of the enteric nervous system derives from the "vagal" neural crest, lying at the level of somites 1-7, which invades the digestive tract rostro-caudally from the foregut to the hindgut. Little is known about the initial phase of this colonization, which brings enteric precursors into the foregut. Here we show that the "vagal crest" subsumes two populations of enteric precursors with contrasted origins, initial modes of migration, and destinations. Crest cells adjacent to somites 1 and 2 produce Schwann cell precursors that colonize the vagus nerve, which in turn guides them into the esophagus and stomach. Crest cells adjacent to somites 3-7 belong to the crest streams contributing to sympathetic chains: they migrate ventrally, seed the sympathetic chains, and colonize the entire digestive tract thence. Accordingly, enteric ganglia, like sympathetic ones, are atrophic when deprived of signaling through the tyrosine kinase receptor ErbB3, while half of the esophageal ganglia require, like parasympathetic ones, the nerve-associated form of the ErbB3 ligand, Neuregulin-1. These dependencies might bear relevance to Hirschsprung disease, with which alleles of Neuregulin-1 are associated."		* '''Dual origin of enteric neurons in vagal Schwann cell precursors and the sympathetic neural crest'''{{#pmid:29078343\|PMID29078343}} "Most of the enteric nervous system derives from the "vagal" neural crest, lying at the level of somites 1-7, which invades the digestive tract rostro-caudally from the foregut to the hindgut. Little is known about the initial phase of this colonization, which brings enteric precursors into the foregut. Here we show that the "vagal crest" subsumes two populations of enteric precursors with contrasted origins, initial modes of migration, and destinations. Crest cells adjacent to somites 1 and 2 produce Schwann cell precursors that colonize the vagus nerve, which in turn guides them into the esophagus and stomach. Crest cells adjacent to somites 3-7 belong to the crest streams contributing to sympathetic chains: they migrate ventrally, seed the sympathetic chains, and colonize the entire digestive tract thence. Accordingly, enteric ganglia, like sympathetic ones, are atrophic when deprived of signaling through the tyrosine kinase receptor ErbB3, while half of the esophageal ganglia require, like parasympathetic ones, the nerve-associated form of the ErbB3 ligand, Neuregulin-1. These dependencies might bear relevance to Hirschsprung disease, with which alleles of Neuregulin-1 are associated."

	* '''How Schwann Cells Sort Axons: New Concepts'''{{#pmid:25686621\|PMID25686621}} "Peripheral nerves contain large myelinated and small unmyelinated (Remak) fibers that perform different functions. The choice to myelinate or not is dictated to Schwann cells by the axon itself, based on the amount of neuregulin I-type III exposed on its membrane. Peripheral axons are more important in determining the final myelination fate than central axons, and the implications for this difference in Schwann cells and oligodendrocytes are discussed. Interestingly, this choice is reversible during pathology, accounting for the remarkable plasticity of Schwann cells, and contributing to the regenerative potential of the peripheral nervous system. Radial sorting is the process by which Schwann cells choose larger axons to myelinate during development."
	\|}		\|}
	{\| class="wikitable mw-collapsible mw-collapsed"		{\| class="wikitable mw-collapsible mw-collapsed"
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	\|-		\|-
	\| {{Older papers}}		\| {{Older papers}}
			* '''How Schwann Cells Sort Axons: New Concepts'''{{#pmid:25686621\|PMID25686621}} "Peripheral nerves contain large myelinated and small unmyelinated (Remak) fibers that perform different functions. The choice to myelinate or not is dictated to Schwann cells by the axon itself, based on the amount of neuregulin I-type III exposed on its membrane. Peripheral axons are more important in determining the final myelination fate than central axons, and the implications for this difference in Schwann cells and oligodendrocytes are discussed. Interestingly, this choice is reversible during pathology, accounting for the remarkable plasticity of Schwann cells, and contributing to the regenerative potential of the peripheral nervous system. Radial sorting is the process by which Schwann cells choose larger axons to myelinate during development."

	* '''Neural crest origin of olfactory ensheathing glia'''{{#pmid:21078992\|PMID21078992}} "Olfactory ensheathing cells (OECs) are a unique class of glial cells with exceptional translational potential because of their ability to support axon regeneration in the central nervous system. Although OECs are similar in many ways to immature and nonmyelinating Schwann cells, and can myelinate large-diameter axons indistinguishably from myelination by Schwann cells, current dogma holds that OECs arise from the olfactory epithelium. Here, using fate-mapping techniques in chicken embryos and genetic lineage tracing in mice, we show that OECs in fact originate from the neural crest and hence share a common developmental heritage with Schwann cells."		* '''Neural crest origin of olfactory ensheathing glia'''{{#pmid:21078992\|PMID21078992}} "Olfactory ensheathing cells (OECs) are a unique class of glial cells with exceptional translational potential because of their ability to support axon regeneration in the central nervous system. Although OECs are similar in many ways to immature and nonmyelinating Schwann cells, and can myelinate large-diameter axons indistinguishably from myelination by Schwann cells, current dogma holds that OECs arise from the olfactory epithelium. Here, using fate-mapping techniques in chicken embryos and genetic lineage tracing in mice, we show that OECs in fact originate from the neural crest and hence share a common developmental heritage with Schwann cells."

Z8600021 at 00:05, 5 February 2020

2020-02-05T00:05:07Z

← Older revision		Revision as of 11:05, 5 February 2020
Line 2:		Line 2:
	==Introduction==		==Introduction==
	{\|		{\|
	\| Schwann cells are glial cells that originate and development from {{neural crest}} cells migrating out along the developing nerve fibers. These cells differentiate to wrap around nerve axon processes to form myelin sheaths that improve nerve conduction. This process of myelination occurs also within the central nervous system by another population of glial cells. (More? {{gliogenesis}})		\| Schwann cells are glial cells that originate and development from {{neural crest}} cells migrating out along the developing nerve fibers. These cells differentiate to wrap around nerve axon processes to form myelin sheaths that improve nerve conduction. This process of myelination occurs also within the central nervous system by another population of glial cells, the oligodendrocytes. (More? {{gliogenesis}})

	<br>		<br>

Z8600021 at 23:53, 4 February 2020

2020-02-04T23:53:19Z

← Older revision		Revision as of 10:53, 5 February 2020
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	<br>		<br>
	~~:'''Links:''' {{gliogenesis}}~~
	\| [[File:Myelination animation.gif]]		\| [[File:Myelination animation.gif]]

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	\| Schwann cells are named after Theodor Schwann (1810 - 1882) a German physiologist.		\| Schwann cells are named after Theodor Schwann (1810 - 1882) a German physiologist.
	\|}		\|}
			<br>
			{{Glia Links}}

	<br>		<br>
	{{Neural Crest Links}}		{{Neural Crest Links}}

Z8600021 at 03:08, 13 Haziran 2019

2019-06-13T03:08:20Z

← Older revision		Revision as of 14:08, 13 Haziran 2019
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	* '''How Schwann Cells Sort Axons: New Concepts'''{{#pmid:25686621\|PMID25686621}} "Peripheral nerves contain large myelinated and small unmyelinated (Remak) fibers that perform different functions. The choice to myelinate or not is dictated to Schwann cells by the axon itself, based on the amount of neuregulin I-type III exposed on its membrane. Peripheral axons are more important in determining the final myelination fate than central axons, and the implications for this difference in Schwann cells and oligodendrocytes are discussed. Interestingly, this choice is reversible during pathology, accounting for the remarkable plasticity of Schwann cells, and contributing to the regenerative potential of the peripheral nervous system. Radial sorting is the process by which Schwann cells choose larger axons to myelinate during development."		* '''How Schwann Cells Sort Axons: New Concepts'''{{#pmid:25686621\|PMID25686621}} "Peripheral nerves contain large myelinated and small unmyelinated (Remak) fibers that perform different functions. The choice to myelinate or not is dictated to Schwann cells by the axon itself, based on the amount of neuregulin I-type III exposed on its membrane. Peripheral axons are more important in determining the final myelination fate than central axons, and the implications for this difference in Schwann cells and oligodendrocytes are discussed. Interestingly, this choice is reversible during pathology, accounting for the remarkable plasticity of Schwann cells, and contributing to the regenerative potential of the peripheral nervous system. Radial sorting is the process by which Schwann cells choose larger axons to myelinate during development."

	* '''Schwann cell precursors from nerve innervation are a cellular origin of melanocytes in skin'''{{#pmid:19837037\|PMID19837037}} "Current opinion holds that pigment cells, melanocytes, are derived from neural crest cells produced at the dorsal neural tube and that migrate under the epidermis to populate all parts of the skin. Here, we identify growing nerves projecting throughout the body as a stem/progenitor niche containing Schwann cell precursors (SCPs) from which large numbers of skin melanocytes originate. SCPs arise as a result of lack of neuronal specification by Hmx1 homeobox gene function in the neural crest ventral migratory pathway. Schwann cell and melanocyte development share signaling molecules with both the glial and melanocyte cell fates intimately linked to nerve contact and regulated in an opposing manner by Neuregulin and soluble signals including insulin-like growth factor and platelet-derived growth factor. These results reveal SCPs as a cellular origin of melanocytes, and have broad implications on the molecular mechanisms regulating skin pigmentation during development, in health and pigmentation disorders."

	* '''Neural crest origin of olfactory ensheathing glia'''{{#pmid:21078992\|PMID21078992}} "Olfactory ensheathing cells (OECs) are a unique class of glial cells with exceptional translational potential because of their ability to support axon regeneration in the central nervous system. Although OECs are similar in many ways to immature and nonmyelinating Schwann cells, and can myelinate large-diameter axons indistinguishably from myelination by Schwann cells, current dogma holds that OECs arise from the olfactory epithelium. Here, using fate-mapping techniques in chicken embryos and genetic lineage tracing in mice, we show that OECs in fact originate from the neural crest and hence share a common developmental heritage with Schwann cells."
	\|}		\|}
	{\| class="wikitable mw-collapsible mw-collapsed"		{\| class="wikitable mw-collapsible mw-collapsed"
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	\| [[File:Mark_Hill.jpg\|90px\|left]] {{Most_Recent_Refs}}		\| [[File:Mark_Hill.jpg\|90px\|left]] {{Most_Recent_Refs}}

	Search term: [http://www.ncbi.nlm.nih.gov/pubmed/?term=Schwann+Cell+Development ''Schwann Cell Development'']		Search term: [http://www.ncbi.nlm.nih.gov/pubmed/?term=Schwann+Cell+Development ''Schwann Cell Development''] \| [http://www.ncbi.nlm.nih.gov/pubmed/?term=Peripheral+Myelination+Development ''Peripheral Myelination Development'']

	\|}		\|}
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	\|-		\|-
	\| {{Older papers}}		\| {{Older papers}}
			* '''Neural crest origin of olfactory ensheathing glia'''{{#pmid:21078992\|PMID21078992}} "Olfactory ensheathing cells (OECs) are a unique class of glial cells with exceptional translational potential because of their ability to support axon regeneration in the central nervous system. Although OECs are similar in many ways to immature and nonmyelinating Schwann cells, and can myelinate large-diameter axons indistinguishably from myelination by Schwann cells, current dogma holds that OECs arise from the olfactory epithelium. Here, using fate-mapping techniques in chicken embryos and genetic lineage tracing in mice, we show that OECs in fact originate from the neural crest and hence share a common developmental heritage with Schwann cells."

			* '''Schwann cell precursors from nerve innervation are a cellular origin of melanocytes in skin'''{{#pmid:19837037\|PMID19837037}} "Current opinion holds that pigment cells, melanocytes, are derived from neural crest cells produced at the dorsal neural tube and that migrate under the epidermis to populate all parts of the skin. Here, we identify growing nerves projecting throughout the body as a stem/progenitor niche containing Schwann cell precursors (SCPs) from which large numbers of skin melanocytes originate. SCPs arise as a result of lack of neuronal specification by Hmx1 homeobox gene function in the neural crest ventral migratory pathway. Schwann cell and melanocyte development share signaling molecules with both the glial and melanocyte cell fates intimately linked to nerve contact and regulated in an opposing manner by Neuregulin and soluble signals including insulin-like growth factor and platelet-derived growth factor. These results reveal SCPs as a cellular origin of melanocytes, and have broad implications on the molecular mechanisms regulating skin pigmentation during development, in health and pigmentation disorders."
	\|}		\|}

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	===Search PubMed===		===Search PubMed===

	~~Search Dec 2010 "Schwann Cell Development" All (4257) Review (571) Free Full Text (851)~~


	'''Search Pubmed:''' [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=search&term=Schwann%20Cell%20Development Schwann Cell Development] \| [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=search&term=Schwann%20Cell Schwann Cell] \| [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=search&term=Schwann%20Myelination%20Development Schwann Myelination Development]		'''Search Pubmed:''' [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=search&term=Schwann%20Cell%20Development Schwann Cell Development] \| [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=search&term=Schwann%20Cell Schwann Cell] \| [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=search&term=Schwann%20Myelination%20Development Schwann Myelination Development]

Z8600021 at 03:05, 13 Haziran 2019

2019-06-13T03:05:25Z

← Older revision		Revision as of 14:05, 13 Haziran 2019
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	{\|		{\|
	\|+ Historic Embryology		\|+ Historic Embryology
	\|-		\|-bgcolor="FAF5FF"
	\| width=~~85px~~\|[[File:Theodor Schwann.jpg\|~~80px~~]]		\| width=65px\|[[File:Theodor Schwann.jpg\|60px]]
	\| Schwann cells are named after Theodor Schwann (1810 - 1882) a German physiologist.		\| Schwann cells are named after Theodor Schwann (1810 - 1882) a German physiologist.
	\|}		\|}

Z8600021 at 03:04, 13 Haziran 2019

2019-06-13T03:04:52Z

← Older revision		Revision as of 14:04, 13 Haziran 2019
Line 11:		Line 11:
	\|}		\|}
	{\|		{\|
	\| [[File:Theodor Schwann.jpg\|80px]]		\|+ Historic Embryology
			\|-
			\| width=85px\|[[File:Theodor Schwann.jpg\|80px]]
	\| Schwann cells are named after Theodor Schwann (1810 - 1882) a German physiologist.		\| Schwann cells are named after Theodor Schwann (1810 - 1882) a German physiologist.
	\|}		\|}

Z8600021 at 21:31, 25 Mayıs 2019

2019-05-25T21:31:01Z

← Older revision		Revision as of 08:31, 26 Mayıs 2019
Line 3:		Line 3:
	{\|		{\|
	\| Schwann cells are glial cells that originate and development from {{neural crest}} cells migrating out along the developing nerve fibers. These cells differentiate to wrap around nerve axon processes to form myelin sheaths that improve nerve conduction. This process of myelination occurs also within the central nervous system by another population of glial cells. (More? {{gliogenesis}})		\| Schwann cells are glial cells that originate and development from {{neural crest}} cells migrating out along the developing nerve fibers. These cells differentiate to wrap around nerve axon processes to form myelin sheaths that improve nerve conduction. This process of myelination occurs also within the central nervous system by another population of glial cells. (More? {{gliogenesis}})

			<br>
			:'''Links:''' {{gliogenesis}}
	\| [[File:Myelination animation.gif]]		\| [[File:Myelination animation.gif]]

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	<br>		<br>
	{{Neural Crest Links}}		{{Neural Crest Links}}
	~~<br>~~
	~~{{gliogenesis}}~~
	== Some Recent Findings ==		== Some Recent Findings ==
	{\|		{\|

Z8600021 at 21:21, 25 Mayıs 2019

2019-05-25T21:21:47Z

← Older revision		Revision as of 08:21, 26 Mayıs 2019
Line 2:		Line 2:
	==Introduction==		==Introduction==
	{\|		{\|
	\| Schwann cells are glial cells that originate and development from {{neural crest}} cells migrating out along the developing nerve fibers. These cells differentiate to wrap around nerve axon processes to form myelin sheaths that improve nerve conduction. This process of myelination occurs also within the central nervous system by another population of glial cells. (More? {{gliogenesis}})		\| Schwann cells are glial cells that originate and development from {{neural crest}} cells migrating out along the developing nerve fibers. These cells differentiate to wrap around nerve axon processes to form myelin sheaths that improve nerve conduction. This process of myelination occurs also within the central nervous system by another population of glial cells. (More? {{gliogenesis}})
	\| [[File:Myelination animation.gif]]		\| [[File:Myelination animation.gif]]

Line 8:		Line 8:
	\|}		\|}
	{\|		{\|
	\| [[File:Theodor Schwann.jpg\|~~150px~~]]		\| [[File:Theodor Schwann.jpg\|80px]]
	\| Schwann cells are named after Theodor Schwann (1810 - 1882) a German physiologist.		\| Schwann cells are named after Theodor Schwann (1810 - 1882) a German physiologist.
	\|}		\|}
	<br>		<br>
	{{Neural Crest Links}}		{{Neural Crest Links}}
			<br>
	{{gliogenesis}}		{{gliogenesis}}
	== Some Recent Findings ==		== Some Recent Findings ==

Z8600021 at 21:21, 25 Mayıs 2019

2019-05-25T21:21:12Z

← Older revision		Revision as of 08:21, 26 Mayıs 2019
Line 9:		Line 9:
	{\|		{\|
	\| [[File:Theodor Schwann.jpg\|150px]]		\| [[File:Theodor Schwann.jpg\|150px]]
	\| ~~The~~ cells are named after ~~their original discoverer a German physiologist~~ Theodor Schwann (1810 - 1882).		\| Schwann cells are named after Theodor Schwann (1810 - 1882) a German physiologist.
	\|}		\|}
	<br>		<br>
	{{Neural Crest Links}}		{{Neural Crest Links}}

			{{gliogenesis}}
	== Some Recent Findings ==		== Some Recent Findings ==
	{\|		{\|