Neural - Prosencephalon Development - Revision history

Z8600021 at 23:17, 13 Mayıs 2020

2020-05-13T23:17:47Z

← Older revision		Revision as of 09:17, 14 Mayıs 2020
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			* '''The genetic architecture of the human cerebral cortex'''{{#pmid:32193296\|PMID32193296}} "The cerebral cortex underlies our complex cognitive capabilities, yet little is known about the specific genetic loci that influence human cortical structure. To identify genetic variants that affect cortical structure, we conducted a genome-wide association meta-analysis of brain magnetic resonance imaging data from 51,665 individuals. We analyzed the surface area and average thickness of the whole cortex and 34 regions with known functional specializations. We identified 199 significant loci and found significant enrichment for loci influencing total surface area within regulatory elements that are active during prenatal cortical development, supporting the radial unit hypothesis. Loci that affect regional surface area cluster near genes in Wnt signaling pathways, which influence progenitor expansion and areal identity. Variation in cortical structure is genetically correlated with cognitive function, Parkinson's disease, insomnia, depression, neuroticism, and attention deficit hyperactivity disorder."

	* '''Development of laminar organization of the fetal cerebrum'''{{#pmid:20981415\|PMID20981415}} "Heads of 131 fetal specimens of 14-40 weeks gestational age (GA) were scanned by 3.0T MRI. Eleven fetal specimens of 14-27 weeks GA were scanned by 7.0T MRI. On T(1)-weighted 3.0T MRI, layers could be visualized at 14 weeks GA and appeared clearer after 18 weeks GA. On 7.0T MRI, four zones could be recognized at 14 weeks GA. During 15-22 weeks GA, when laminar organization appeared typical, seven layers including the periventricular zone and external capsule fibers could be differentiated, which corresponded to seven zones in histological stained sections. At 23-28 weeks GA, laminar organization appeared less typical, and borderlines among them appeared obscured. After 30 weeks GA, it disappeared and turned into mature-like structures. The developing lamination appeared the most distinguishable at the parieto-occipital part of brain and peripheral regions of the hippocampus. The migrating thalamocortical afferents were probably delineated as a high signal layer located at the lower, middle, and upper part of the subplate zone at 16-28 weeks GA on T(1)-weighted 3.0T MRI."		* '''Development of laminar organization of the fetal cerebrum'''{{#pmid:20981415\|PMID20981415}} "Heads of 131 fetal specimens of 14-40 weeks gestational age (GA) were scanned by 3.0T MRI. Eleven fetal specimens of 14-27 weeks GA were scanned by 7.0T MRI. On T(1)-weighted 3.0T MRI, layers could be visualized at 14 weeks GA and appeared clearer after 18 weeks GA. On 7.0T MRI, four zones could be recognized at 14 weeks GA. During 15-22 weeks GA, when laminar organization appeared typical, seven layers including the periventricular zone and external capsule fibers could be differentiated, which corresponded to seven zones in histological stained sections. At 23-28 weeks GA, laminar organization appeared less typical, and borderlines among them appeared obscured. After 30 weeks GA, it disappeared and turned into mature-like structures. The developing lamination appeared the most distinguishable at the parieto-occipital part of brain and peripheral regions of the hippocampus. The migrating thalamocortical afferents were probably delineated as a high signal layer located at the lower, middle, and upper part of the subplate zone at 16-28 weeks GA on T(1)-weighted 3.0T MRI."
	\|}		\|}

Z8600021 at 00:26, 2 March 2020

2020-03-02T00:26:23Z

← Older revision		Revision as of 10:26, 2 March 2020
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	{{Neural Links 2}}		{{Neural Links 2}}
	==Some Recent Findings==		==Some Recent Findings==
	[[File:Mouse - forebrain Robo3 expression.jpg\|thumb\|Developing mouse forebrain Robo3 expression~~<ref><pubmed>~~19366869~~</pubmed>~~\| ~~[http://cercor.oxfordjournals.org/content/19/suppl_1/i22.long Cereb Cortex.]~~		[[File:Mouse - forebrain Robo3 expression.jpg\|thumb\|Developing mouse forebrain Robo3 expression{{#pmid:19366869\|PMID19366869}}]]
	~~</ref>~~]]
	{\|		{\|
	\|-bgcolor="F5FAFF"		\|-bgcolor="F5FAFF"
	\|		\|
	* '''Development of laminar organization of the fetal cerebrum'''~~<ref><pubmed>~~20981415~~</pubmed></ref>~~ "Heads of 131 fetal specimens of 14-40 weeks gestational age (GA) were scanned by 3.0T MRI. Eleven fetal specimens of 14-27 weeks GA were scanned by 7.0T MRI. On T(1)-weighted 3.0T MRI, layers could be visualized at 14 weeks GA and appeared clearer after 18 weeks GA. On 7.0T MRI, four zones could be recognized at 14 weeks GA. During 15-22 weeks GA, when laminar organization appeared typical, seven layers including the periventricular zone and external capsule fibers could be differentiated, which corresponded to seven zones in histological stained sections. At 23-28 weeks GA, laminar organization appeared less typical, and borderlines among them appeared obscured. After 30 weeks GA, it disappeared and turned into mature-like structures. The developing lamination appeared the most distinguishable at the parieto-occipital part of brain and peripheral regions of the hippocampus. The migrating thalamocortical afferents were probably delineated as a high signal layer located at the lower, middle, and upper part of the subplate zone at 16-28 weeks GA on T(1)-weighted 3.0T MRI."		* '''Development of laminar organization of the fetal cerebrum'''{{#pmid:20981415\|PMID20981415}} "Heads of 131 fetal specimens of 14-40 weeks gestational age (GA) were scanned by 3.0T MRI. Eleven fetal specimens of 14-27 weeks GA were scanned by 7.0T MRI. On T(1)-weighted 3.0T MRI, layers could be visualized at 14 weeks GA and appeared clearer after 18 weeks GA. On 7.0T MRI, four zones could be recognized at 14 weeks GA. During 15-22 weeks GA, when laminar organization appeared typical, seven layers including the periventricular zone and external capsule fibers could be differentiated, which corresponded to seven zones in histological stained sections. At 23-28 weeks GA, laminar organization appeared less typical, and borderlines among them appeared obscured. After 30 weeks GA, it disappeared and turned into mature-like structures. The developing lamination appeared the most distinguishable at the parieto-occipital part of brain and peripheral regions of the hippocampus. The migrating thalamocortical afferents were probably delineated as a high signal layer located at the lower, middle, and upper part of the subplate zone at 16-28 weeks GA on T(1)-weighted 3.0T MRI."
	\|}		\|}
	{\| class="wikitable mw-collapsible mw-collapsed"		{\| class="wikitable mw-collapsible mw-collapsed"
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	\| [[File:Mark_Hill.jpg\|90px\|left]] {{Most_Recent_Refs}}		\| [[File:Mark_Hill.jpg\|90px\|left]] {{Most_Recent_Refs}}

	Search term: [http://www.ncbi.nlm.nih.gov/pubmed/?term=Prosencephalon+Development ''Prosencephalon Development''] \| [http://www.ncbi.nlm.nih.gov/pubmed/?term=Prosencephalon+Embryology ''Prosencephalon Embryology'']		Search term: [http://www.ncbi.nlm.nih.gov/pubmed/?term=Prosencephalon+Development ''Prosencephalon Development''] \| [http://www.ncbi.nlm.nih.gov/pubmed/?term=Prosencephalon+Embryology ''Prosencephalon Embryology''] \| [http://www.ncbi.nlm.nih.gov/pubmed/?term=Prosencephalon ''Prosencephalon'']

	\|}		\|}
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	===Reviews===		===Reviews===

	~~<pubmed>~~19560042~~</pubmed>~~		{{#pmid:19560042}}
	~~<pubmed>~~17275286~~</pubmed>~~
	~~<pubmed>~~17030124~~</pubmed>~~		{{#pmid:17275286}}
	~~<pubmed>~~16418000~~</pubmed>~~
	~~<pubmed>~~12626695~~</pubmed>~~		{{#pmid:17030124}}
	~~<pubmed>~~12461551~~</pubmed>~~
			{{#pmid:16418000}}

			{{#pmid:12626695}}

			{{#pmid:12461551}}

	===Articles===		===Articles===

	~~<pubmed>~~11955708~~</pubmed>~~		{{#pmid:11955708}}
	~~<pubmed>~~11803577~~</pubmed>~~
	~~<pubmed>~~11734354~~</pubmed>~~		{{#pmid:11803577}}
	~~<pubmed>~~10473296~~</pubmed>~~
	~~<pubmed>~~10375509~~</pubmed>~~		{{#pmid:11734354}}
	~~<pubmed>~~9810564~~</pubmed>~~
	~~<pubmed>~~1661870~~</pubmed>~~		{{#pmid:10473296}}
	~~<pubmed>~~4018406~~</pubmed>~~
			{{#pmid:10375509}}

			{{#pmid:9810564}}

			{{#pmid:1661870}}

			{{#pmid:4018406}}

	===Search PubMed===		===Search PubMed===

Z8600021 at 00:21, 2 March 2020

2020-03-02T00:21:03Z

← Older revision		Revision as of 10:21, 2 March 2020
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	\|}		\|}
	{\| class="wikitable mw-collapsible mw-collapsed"		{\| class="wikitable mw-collapsible mw-collapsed"
	! More recent papers		! More recent papers
	\|-		\|-
	\| [[File:Mark_Hill.jpg\|90px\|left]] {{Most_Recent_Refs}}		\| [[File:Mark_Hill.jpg\|90px\|left]] {{Most_Recent_Refs}}

	Search term: [http://www.ncbi.nlm.nih.gov/pubmed/?term=Prosencephalon+Embryology ''Prosencephalon Embryology'']		Search term: [http://www.ncbi.nlm.nih.gov/pubmed/?term=Prosencephalon+Development ''Prosencephalon Development''] \| [http://www.ncbi.nlm.nih.gov/pubmed/?term=Prosencephalon+Embryology ''Prosencephalon Embryology'']

			\|}
			{\| class="wikitable mw-collapsible mw-collapsed"
			! Older papers
			\|-
			\| {{Older papers}}

	~~<pubmed limit=5>Prosencephalon Embryology</pubmed>~~
	\|}		\|}
	== Development Overview ==		== Development Overview ==

Z8600021 at 07:26, 8 Ocak 2015

2015-01-08T07:26:10Z

← Older revision		Revision as of 17:26, 8 Ocak 2015
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	==Additional Images==		==Additional Images==

	===~~Historical~~===		===Historic===
	Keith, A. [[Book - Human Embryology and Morphology (1921)\|'''Human Embryology And Morphology''']] (1921) Longmans, Green & Co.:New York. [[Human Embryology and Morphology_9\|9 Fore-Brain]] and [[Human Embryology and Morphology_10\|10 Fore-Brain Cerebral Vesicles]]		{\| class="wikitable mw-collapsible mw-collapsed"
			! Human Embryology And Morphology (1921)
			\|-
			\| Keith, A. [[Book - Human Embryology and Morphology (1921)\|'''Human Embryology And Morphology''']] (1921) Longmans, Green & Co.:New York.

			[[Human Embryology and Morphology_9\|9 Fore-Brain]] and [[Human Embryology and Morphology_10\|10 Fore-Brain Cerebral Vesicles]]

	<gallery>		<gallery>
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	File:Keith1921 fig129.jpg\|Fig. 129. The Primitive Vein of the Head and its tributaries in the 6th week		File:Keith1921 fig129.jpg\|Fig. 129. The Primitive Vein of the Head and its tributaries in the 6th week
	</gallery>		</gallery>
			\|}

	== References ==		== References ==

Z8600021 at 07:22, 8 Ocak 2015

2015-01-08T07:22:19Z

@@ Line 39: / Line 39: @@
-{{Template:Neural Table}}
+{{Neural Table}}
 ==Primary Vesicles==
 [[File:Stage 13 image 098.jpg|thumb|300px|Brain primary vesicle development ([[Carnegie stage 13]])]]
 [[Image:CNS primary vesicles.jpg|600px]]
 == References ==

Z8600021 at 09:15, 21 Haziran 2014

2014-06-21T09:15:28Z

← Older revision		Revision as of 19:15, 21 Haziran 2014
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	* '''Development of laminar organization of the fetal cerebrum'''<ref><pubmed>20981415</pubmed></ref> "Heads of 131 fetal specimens of 14-40 weeks gestational age (GA) were scanned by 3.0T MRI. Eleven fetal specimens of 14-27 weeks GA were scanned by 7.0T MRI. On T(1)-weighted 3.0T MRI, layers could be visualized at 14 weeks GA and appeared clearer after 18 weeks GA. On 7.0T MRI, four zones could be recognized at 14 weeks GA. During 15-22 weeks GA, when laminar organization appeared typical, seven layers including the periventricular zone and external capsule fibers could be differentiated, which corresponded to seven zones in histological stained sections. At 23-28 weeks GA, laminar organization appeared less typical, and borderlines among them appeared obscured. After 30 weeks GA, it disappeared and turned into mature-like structures. The developing lamination appeared the most distinguishable at the parieto-occipital part of brain and peripheral regions of the hippocampus. The migrating thalamocortical afferents were probably delineated as a high signal layer located at the lower, middle, and upper part of the subplate zone at 16-28 weeks GA on T(1)-weighted 3.0T MRI."		* '''Development of laminar organization of the fetal cerebrum'''<ref><pubmed>20981415</pubmed></ref> "Heads of 131 fetal specimens of 14-40 weeks gestational age (GA) were scanned by 3.0T MRI. Eleven fetal specimens of 14-27 weeks GA were scanned by 7.0T MRI. On T(1)-weighted 3.0T MRI, layers could be visualized at 14 weeks GA and appeared clearer after 18 weeks GA. On 7.0T MRI, four zones could be recognized at 14 weeks GA. During 15-22 weeks GA, when laminar organization appeared typical, seven layers including the periventricular zone and external capsule fibers could be differentiated, which corresponded to seven zones in histological stained sections. At 23-28 weeks GA, laminar organization appeared less typical, and borderlines among them appeared obscured. After 30 weeks GA, it disappeared and turned into mature-like structures. The developing lamination appeared the most distinguishable at the parieto-occipital part of brain and peripheral regions of the hippocampus. The migrating thalamocortical afferents were probably delineated as a high signal layer located at the lower, middle, and upper part of the subplate zone at 16-28 weeks GA on T(1)-weighted 3.0T MRI."
	\|}		\|}
			{\| class="wikitable mw-collapsible mw-collapsed"
			! More recent papers
			\|-
			\| [[File:Mark_Hill.jpg\|90px\|left]] {{Most_Recent_Refs}}

			Search term: [http://www.ncbi.nlm.nih.gov/pubmed/?term=Prosencephalon+Embryology ''Prosencephalon Embryology'']

			<pubmed limit=5>Prosencephalon Embryology</pubmed>
			\|}
	== Development Overview ==		== Development Overview ==
	Neuralation begins at the trilaminar embryo with formation of the notochord and somites, both of which underly the ectoderm and do not contribute to the nervous system, but are involved with patterning its initial formation. The central portion of the ectoderm then forms the neural plate that folds to form the neural tube, that will eventually form the entire central nervous system.		Neuralation begins at the trilaminar embryo with formation of the notochord and somites, both of which underly the ectoderm and do not contribute to the nervous system, but are involved with patterning its initial formation. The central portion of the ectoderm then forms the neural plate that folds to form the neural tube, that will eventually form the entire central nervous system.

Z8600021 at 10:39, 11 March 2014

2014-03-11T10:39:07Z

← Older revision		Revision as of 20:39, 11 March 2014
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	{{Neural Links}}		{{Neural Links}}

			{{Neural Links 2}}
	==Some Recent Findings==		==Some Recent Findings==
	[[File:Mouse - forebrain Robo3 expression.jpg\|thumb\|Developing mouse forebrain Robo3 expression<ref><pubmed>19366869</pubmed>\| [http://cercor.oxfordjournals.org/content/19/suppl_1/i22.long Cereb Cortex.]		[[File:Mouse - forebrain Robo3 expression.jpg\|thumb\|Developing mouse forebrain Robo3 expression<ref><pubmed>19366869</pubmed>\| [http://cercor.oxfordjournals.org/content/19/suppl_1/i22.long Cereb Cortex.]

Z8600021 at 10:37, 11 March 2014

2014-03-11T10:37:53Z

← Older revision		Revision as of 20:37, 11 March 2014
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	<div style="background:#F5FFFA; border: 1px solid #CEF2E0; padding: 1em; margin: auto; width: 98%; float:left;"><div style="margin:0;background-color:#cef2e0;font-family:sans-serif;font-size:120%;font-weight:bold;border:1px solid #a3bfb1;text-align:left;color:#000;padding-left:0.4em;padding-top:0.2em;padding-bottom:0.2em;">Notice - Mark Hill</div>Currently this is only a template page and is being updated (this notice removed when completed).</div>		{{Header}}

	==Introduction==		==Introduction==
	[[File:Stage10_sem6.jpg\|right\|150px]]		[[File:Stage10_sem6.jpg\|right\|150px]]
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	~~:{{Template:Neural Links}}~~

			{{Neural Links}}
	==Some Recent Findings==		==Some Recent Findings==
	[[File:Mouse - forebrain Robo3 expression.jpg\|thumb\|Developing mouse forebrain Robo3 expression<ref><pubmed>19366869</pubmed>\| [http://cercor.oxfordjournals.org/content/19/suppl_1/i22.long Cereb Cortex.]		[[File:Mouse - forebrain Robo3 expression.jpg\|thumb\|Developing mouse forebrain Robo3 expression<ref><pubmed>19366869</pubmed>\| [http://cercor.oxfordjournals.org/content/19/suppl_1/i22.long Cereb Cortex.]
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	{{~~Template:~~Glossary}}		{{Glossary}}


	{{~~Template:~~Footer}}		{{Footer}}

S8600021: /* Primary Vesicles */

2010-11-08T02:28:23Z

Primary Vesicles

← Older revision		Revision as of 12:28, 8 November 2010
Line 33:		Line 33:

	==Primary Vesicles==		==Primary Vesicles==
	[[File:Stage 13 image 098.jpg\|thumb\|Brain primary vesicle development ([[Carnegie stage 13]])]]		[[File:Stage 13 image 098.jpg\|thumb\|300px\|Brain primary vesicle development ([[Carnegie stage 13]])]]
	[[Image:CNS primary vesicles.jpg\|600px]]		[[Image:CNS primary vesicles.jpg\|600px]]

S8600021: /* Primary Vesicles */

2010-11-08T02:27:03Z

Primary Vesicles

← Older revision		Revision as of 12:27, 8 November 2010
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	==Primary Vesicles==		==Primary Vesicles==
			[[File:Stage 13 image 098.jpg\|thumb\|Brain primary vesicle development ([[Carnegie stage 13]])]]
	[[Image:CNS primary vesicles.jpg\|600px]]		[[Image:CNS primary vesicles.jpg\|600px]]


	== References ==		== References ==