Mouse Estrous Cycle - Revision history

Z8600021 at 22:57, 25 April 2018

2018-04-25T22:57:00Z

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 == Mouse Estrous Cycle ==
 {{Mouse Estrous Cycle table}}
 ==Mouse Ovarian Follicle Size==

Z8600021 at 22:53, 25 April 2018

2018-04-25T22:53:45Z

← Older revision		Revision as of 09:53, 26 April 2018
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	Rats and mice are examples of polyestrus mammals (as are cats which are seasonally polyoestrus). Monestrus forms (most wild animals - foxes, bears, wolves etc.) complete a single estrous cycle annually. In the wild, rats and mice probably suspend the cycle for a period during the winter; the reproductive organs are in a state of quiescence, called anestrus.		Rats and mice are examples of polyestrus mammals (as are cats which are seasonally polyoestrus). Monestrus forms (most wild animals - foxes, bears, wolves etc.) complete a single estrous cycle annually. In the wild, rats and mice probably suspend the cycle for a period during the winter; the reproductive organs are in a state of quiescence, called anestrus.

			Note "estrus" the alternate English spelling "oestrus".

			<br>
	{{Mouse links}}		{{Mouse links}}
	==Some Recent Findings==		==Some Recent Findings==
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	\|}		\|}
	== Mouse Estrous Cycle ==		== Mouse Estrous Cycle ==
			{{Mouse Estrous Cycle table}}
	{\| class="pretty table"		{\| class="pretty table"
	\|-bgcolor="CEDFF2"		\|-bgcolor="CEDFF2"

Z8600021 at 22:26, 23 April 2018

2018-04-23T22:26:13Z

← Older revision		Revision as of 09:26, 24 April 2018
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	{{Mouse}}		{{Mouse links}}
	==Some Recent Findings==		==Some Recent Findings==
	[[File:Mouse estrous cycle stage identification.jpg\|thumb\|alt=Mouse estrous cycle stage identification\|Mouse estrous cycle stage identification~~<ref name="PMID22514749"><pubmed>~~22514749~~</pubmed>~~\| ~~[http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0035538 PLoS One.</ref>~~]]		[[File:Mouse estrous cycle stage identification.jpg\|thumb\|alt=Mouse estrous cycle stage identification\|Mouse estrous cycle stage identification{{#pmid:22514749\|PMID22514749}}]]
	{\|		{\|
	\|-bgcolor="F5FAFF"		\|-bgcolor="F5FAFF"
	\|		\|
	* '''Mouse estrous cycle identification tool and images'''~~<ref name="PMID22514749"><pubmed>~~22514749~~</pubmed>~~\| ~~[http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0035538 PLoS One.</ref>~~ "The efficiency of producing timed pregnant or pseudopregnant mice can be increased by identifying those in proestrus or estrus....Presented here are a series of images of the vaginal opening at each stage of the estrous cycle for 3 mouse strains of different coat colors: black (C57BL/6J), agouti (CByB6F1/J) and albino (BALB/cByJ). When all 4 stages (proestrus, estrus, metestrus, and diestrus) need to be identified, vaginal cytology is regarded as the most accurate method. An identification tool is presented to aid the user in determining the stage of estrous when using vaginal cytology. These images and descriptions are an excellent resource for learning how to determine the stage of the estrous cycle by visual observation or vaginal cytology."		* '''Mouse estrous cycle identification tool and images'''{{#pmid:22514749\|PMID22514749}} "The efficiency of producing timed pregnant or pseudopregnant mice can be increased by identifying those in proestrus or estrus....Presented here are a series of images of the vaginal opening at each stage of the estrous cycle for 3 mouse strains of different coat colors: black (C57BL/6J), agouti (CByB6F1/J) and albino (BALB/cByJ). When all 4 stages (proestrus, estrus, metestrus, and diestrus) need to be identified, vaginal cytology is regarded as the most accurate method. An identification tool is presented to aid the user in determining the stage of estrous when using vaginal cytology. These images and descriptions are an excellent resource for learning how to determine the stage of the estrous cycle by visual observation or vaginal cytology."
	* '''Refining timed pregnancies in two strains of genetically engineered mice.''' ~~<ref><pubmed>~~19701181~~</pubmed></ref>~~"In both sEHKO and GFP colonies, increases in body weight at 1 and 2 weeks after timed male exposure more reliably and consistently indicated pregnancy than did plug detection."
	* '''Assessing reproductive status/stages in mice.''' ~~<ref><pubmed>~~19575469~~</pubmed></ref>~~		* '''Refining timed pregnancies in two strains of genetically engineered mice.'''{{#pmid:19701181\|PMID19701181}} "In both sEHKO and GFP colonies, increases in body weight at 1 and 2 weeks after timed male exposure more reliably and consistently indicated pregnancy than did plug detection."
	* '''Uterine NK cells in murine pregnancy.''' ~~<ref><pubmed>~~18284876~~</pubmed></ref>~~"Murine uterine natural killer (uNK) cells are transient, short-lived, terminally differentiated lymphocytes found in decidualized endometrium. ....Activated uNK cells are now considered critical for appropriate endometrial angiogenesis in early implantation site development and in non-gestational endometrium."
	* '''Corpus luteum development: lessons from genetic models in mice.'''~~<ref><pubmed>~~16124996~~</pubmed></ref>~~ "The life span and function of the corpus luteum is regulated by complex interactions between stimulatory (luteotrophic) and inhibitory (luteolytic) mediators. ... In rodents, prolactin is the major luteotrophic hormone by maintaining the structural and functional integrity of the corpus luteum for several days after mating. Other factors involved in steroidogenesis, control of cell cycle, apoptosis, and tissue remodeling have been shown to play a role in corpus luteum development and maintenance. Especially, PGF2alpha seems to be the most potent luteolytic hormone."		* '''Assessing reproductive status/stages in mice.'''{{#pmid:19575469\|PMID19575469}}
	* '''Methodologies to study implantation in mice.'''~~<ref><pubmed>~~16251731~~</pubmed></ref>~~ "....The process of implantation can be postponed and reinstated experimentally by manipulating ovarian estrogen secretion. Stromal decidualization can also be induced experimentally in the hormonally prepared uterus in response to stimuli other than the embryo. ...This chapter describes the routine laboratory methodologies to study the events of early pregnancy, with special emphasis on the implantation process in mice."
			* '''Uterine NK cells in murine pregnancy.'''{{#pmid:18284876\|PMID18284876}} "Murine uterine natural killer (uNK) cells are transient, short-lived, terminally differentiated lymphocytes found in decidualized endometrium. ....Activated uNK cells are now considered critical for appropriate endometrial angiogenesis in early implantation site development and in non-gestational endometrium."

			* '''Corpus luteum development: lessons from genetic models in mice.'''{{#pmid:16124996\|PMID16124996}} "The life span and function of the corpus luteum is regulated by complex interactions between stimulatory (luteotrophic) and inhibitory (luteolytic) mediators. ... In rodents, prolactin is the major luteotrophic hormone by maintaining the structural and functional integrity of the corpus luteum for several days after mating. Other factors involved in steroidogenesis, control of cell cycle, apoptosis, and tissue remodeling have been shown to play a role in corpus luteum development and maintenance. Especially, PGF2alpha seems to be the most potent luteolytic hormone."

			* '''Methodologies to study implantation in mice.'''{{#pmid:16251731\|PMID16251731}} "....The process of implantation can be postponed and reinstated experimentally by manipulating ovarian estrogen secretion. Stromal decidualization can also be induced experimentally in the hormonally prepared uterus in response to stimuli other than the embryo. ...This chapter describes the routine laboratory methodologies to study the events of early pregnancy, with special emphasis on the implantation process in mice."
	\|}		\|}

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	[[File:Mouse ovarian follicle size.jpg]]		[[File:Mouse ovarian follicle size.jpg]]

	Image Source: High-resolution ultrasound biomicroscopy for monitoring ovarian structures in mice. ~~<ref><pubmed>~~19580664~~</pubmed>~~\| ~~[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714516/?tool=pubmed PMC2714516]</ref>~~		Image Source: High-resolution ultrasound biomicroscopy for monitoring ovarian structures in mice.{{#pmid:19580664\|PMID19580664}}

	== Histological Features ==		== Histological Features ==
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	===Reviews===		===Reviews===
	~~<pubmed></pubmed>~~		{{#pmid:25739587}}
	~~<pubmed></pubmed>~~
	~~<pubmed>25739587</pubmed>~~		{{#pmid:23856905}}
	~~<pubmed>~~23856905~~</pubmed>~~
	===Articles===		===Articles===
	~~<pubmed></pubmed>~~		{{#pmid:16023802}}
	~~<pubmed></pubmed>~~
	~~<pubmed>16023802</pubmed>~~		{{#pmid:16251731}}
	~~<pubmed>16251731</pubmed>~~
	~~<pubmed>~~16210782~~</pubmed>~~		{{#pmid:16210782}}
	~~<pubmed>~~15917351~~</pubmed>~~
	~~<pubmed>~~4736343~~</pubmed>~~		{{#pmid:15917351}}

			{{#pmid:4736343}}

	===Search PubMed===		===Search PubMed===

Z8600021 at 06:17, 21 September 2016

2016-09-21T06:17:44Z

← Older revision		Revision as of 17:17, 21 September 2016
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	===Reviews===		===Reviews===
			<pubmed></pubmed>
			<pubmed></pubmed>
			<pubmed>25739587</pubmed>
			<pubmed>23856905</pubmed>
	===Articles===		===Articles===
			<pubmed></pubmed>
			<pubmed></pubmed>
	<pubmed>16023802</pubmed>		<pubmed>16023802</pubmed>
	<pubmed>16251731</pubmed>		<pubmed>16251731</pubmed>
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	===Search PubMed===		===Search PubMed===

	~~Search Nov 2009 "estrous cycle" '''55440''' reference articles of which '''4042''' were reviews.~~

	'''Search PubMed:''' [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=search&term=mouse%20estrous%20cycle mouse estrous cycle] \| [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=search&term=estrous%20cycle estrous cycle] \| [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=search&term=mouse%20anestrus mouse anestrus] \| [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=search&term=oestrous%20cycle oestrous cycle]		'''Search PubMed:''' [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=search&term=mouse%20estrous%20cycle mouse estrous cycle] \| [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=search&term=estrous%20cycle estrous cycle] \| [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=search&term=mouse%20anestrus mouse anestrus] \| [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=search&term=oestrous%20cycle oestrous cycle]

Z8600021 at 06:14, 21 September 2016

2016-09-21T06:14:04Z

← Older revision		Revision as of 17:14, 21 September 2016
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	==Carnegie Stage Species Comparison ==		==Carnegie Stage Species Comparison ==

	~~{{CarnegieComparisonHRM}}~~

	{{Mouse E days}}		{{Mouse E days}}

Z8600021 at 06:13, 21 September 2016

2016-09-21T06:13:14Z

← Older revision		Revision as of 17:13, 21 September 2016
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	{{Mouse E days}}		{{Mouse E days}}



	==References==		==References==

Z8600021 at 06:12, 21 September 2016

2016-09-21T06:12:20Z

← Older revision		Revision as of 17:12, 21 September 2016
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	{{Mouse E days}}		{{Mouse E days}}

	~~{{Mouse Rat Pig table}}~~


	==References==		==References==

	<references/>		<references/>

Z8600021 at 02:25, 21 September 2016

2016-09-21T02:25:07Z

← Older revision		Revision as of 13:25, 21 September 2016
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	{{Mouse}}		{{Mouse}}
	==Some Recent Findings==		==Some Recent Findings==
			[[File:Mouse estrous cycle stage identification.jpg\|thumb\|alt=Mouse estrous cycle stage identification\|Mouse estrous cycle stage identification<ref name="PMID22514749"><pubmed>22514749</pubmed>\| [http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0035538 PLoS One.</ref>]]
	{\|		{\|
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Z8600021 at 02:16, 21 September 2016

2016-09-21T02:16:48Z

← Older revision		Revision as of 13:16, 21 September 2016
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	* '''Mouse estrous cycle identification tool and images'''<ref name="PMID22514749"><pubmed>22514749</pubmed>\| [http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0035538 PLoS One.</ref> "The efficiency of producing timed pregnant or pseudopregnant mice can be increased by identifying those in proestrus or estrus. ~~Visual observation of the vagina is the quickest method, requires no special equipment, and is best used when only proestrus or estrus stages need to be identified~~. ~~Strain to strain differences, especially in coat color can make it difficult to determine the stage of the estrous cycle accurately by visual observation~~. Presented here are a series of images of the vaginal opening at each stage of the estrous cycle for 3 mouse strains of different coat colors: black (C57BL/6J), agouti (CByB6F1/J) and albino (BALB/cByJ). When all 4 stages (proestrus, estrus, metestrus, and diestrus) need to be identified, vaginal cytology is regarded as the most accurate method. An identification tool is presented to aid the user in determining the stage of estrous when using vaginal cytology. These images and descriptions are an excellent resource for learning how to determine the stage of the estrous cycle by visual observation or vaginal cytology."		* '''Mouse estrous cycle identification tool and images'''<ref name="PMID22514749"><pubmed>22514749</pubmed>\| [http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0035538 PLoS One.</ref> "The efficiency of producing timed pregnant or pseudopregnant mice can be increased by identifying those in proestrus or estrus....Presented here are a series of images of the vaginal opening at each stage of the estrous cycle for 3 mouse strains of different coat colors: black (C57BL/6J), agouti (CByB6F1/J) and albino (BALB/cByJ). When all 4 stages (proestrus, estrus, metestrus, and diestrus) need to be identified, vaginal cytology is regarded as the most accurate method. An identification tool is presented to aid the user in determining the stage of estrous when using vaginal cytology. These images and descriptions are an excellent resource for learning how to determine the stage of the estrous cycle by visual observation or vaginal cytology."
	* '''Refining timed pregnancies in two strains of genetically engineered mice.''' <ref><pubmed>19701181</pubmed></ref>"In both sEHKO and GFP colonies, increases in body weight at 1 and 2 weeks after timed male exposure more reliably and consistently indicated pregnancy than did plug detection."		* '''Refining timed pregnancies in two strains of genetically engineered mice.''' <ref><pubmed>19701181</pubmed></ref>"In both sEHKO and GFP colonies, increases in body weight at 1 and 2 weeks after timed male exposure more reliably and consistently indicated pregnancy than did plug detection."
	* '''Assessing reproductive status/stages in mice.''' <ref><pubmed>19575469</pubmed></ref>		* '''Assessing reproductive status/stages in mice.''' <ref><pubmed>19575469</pubmed></ref>

Z8600021 at 02:16, 21 September 2016

2016-09-21T02:16:05Z

← Older revision		Revision as of 13:16, 21 September 2016
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	\|		\|
			* '''Mouse estrous cycle identification tool and images'''<ref name="PMID22514749"><pubmed>22514749</pubmed>\| [http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0035538 PLoS One.</ref> "The efficiency of producing timed pregnant or pseudopregnant mice can be increased by identifying those in proestrus or estrus. Visual observation of the vagina is the quickest method, requires no special equipment, and is best used when only proestrus or estrus stages need to be identified. Strain to strain differences, especially in coat color can make it difficult to determine the stage of the estrous cycle accurately by visual observation. Presented here are a series of images of the vaginal opening at each stage of the estrous cycle for 3 mouse strains of different coat colors: black (C57BL/6J), agouti (CByB6F1/J) and albino (BALB/cByJ). When all 4 stages (proestrus, estrus, metestrus, and diestrus) need to be identified, vaginal cytology is regarded as the most accurate method. An identification tool is presented to aid the user in determining the stage of estrous when using vaginal cytology. These images and descriptions are an excellent resource for learning how to determine the stage of the estrous cycle by visual observation or vaginal cytology."
	* '''Refining timed pregnancies in two strains of genetically engineered mice.''' <ref><pubmed>19701181</pubmed></ref>"In both sEHKO and GFP colonies, increases in body weight at 1 and 2 weeks after timed male exposure more reliably and consistently indicated pregnancy than did plug detection."		* '''Refining timed pregnancies in two strains of genetically engineered mice.''' <ref><pubmed>19701181</pubmed></ref>"In both sEHKO and GFP colonies, increases in body weight at 1 and 2 weeks after timed male exposure more reliably and consistently indicated pregnancy than did plug detection."
	* '''Assessing reproductive status/stages in mice.''' <ref><pubmed>19575469</pubmed></ref>		* '''Assessing reproductive status/stages in mice.''' <ref><pubmed>19575469</pubmed></ref>
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	* '''Methodologies to study implantation in mice.'''<ref><pubmed>16251731</pubmed></ref> "....The process of implantation can be postponed and reinstated experimentally by manipulating ovarian estrogen secretion. Stromal decidualization can also be induced experimentally in the hormonally prepared uterus in response to stimuli other than the embryo. ...This chapter describes the routine laboratory methodologies to study the events of early pregnancy, with special emphasis on the implantation process in mice."		* '''Methodologies to study implantation in mice.'''<ref><pubmed>16251731</pubmed></ref> "....The process of implantation can be postponed and reinstated experimentally by manipulating ovarian estrogen secretion. Stromal decidualization can also be induced experimentally in the hormonally prepared uterus in response to stimuli other than the embryo. ...This chapter describes the routine laboratory methodologies to study the events of early pregnancy, with special emphasis on the implantation process in mice."
	\|}		\|}

	{\| class="wikitable mw-collapsible mw-collapsed"		{\| class="wikitable mw-collapsible mw-collapsed"
	! More recent papers		! More recent papers