Lecture - Renal Development - Revision history

Z8600021 at 23:37, 27 August 2018

2018-08-27T23:37:20Z

← Older revision		Revision as of 09:37, 28 August 2018
Line 15:		Line 15:

	The urinary system is developmentally and anatomically associated with genital development, often described as the urogenital system.		The urinary system is developmentally and anatomically associated with genital development, often described as the urogenital system.
	\|}
	<br>		<br>

	[[Media:ANAT2341Lecture 2018 - Renal Development.pdf\|2018 Lecture - Print PDF]]		[[Media:ANAT2341Lecture 2018 - Renal Development.pdf\|2018 Lecture - Print PDF]]
			\|}
	==Objectives ==		==Objectives ==
	[[File:Stage 13 kidney sections.jpg\|right]]		[[File:Stage 13 kidney sections.jpg\|right]]

2018-08-27T23:35:11Z

← Older revision		Revision as of 09:35, 28 August 2018
Line 18:		Line 18:
	<br>		<br>

			[[Media:ANAT2341Lecture 2018 - Renal Development.pdf\|2018 Lecture - Print PDF]]
	==Objectives ==		==Objectives ==
	[[File:Stage 13 kidney sections.jpg\|right]]		[[File:Stage 13 kidney sections.jpg\|right]]

2018-08-27T22:06:03Z

Nephros Development

← Older revision		Revision as of 08:06, 28 August 2018
Line 148:		Line 148:
	===Pronephros===		===Pronephros===
	* week 3-4 few cells in cervical region (fish type kidney)		* week 3-4 few cells in cervical region (fish type kidney)
	* [[Carnegie stage 9\|Human E19]], Mouse E7.5 - pronephric duct forms first with associated nephrogenic mesenchyme		* [[Carnegie stage 9\|Human E19]], Mouse {{ME7.5}} - pronephric duct forms first with associated nephrogenic mesenchyme
	* grows rostro caudally cervical -> cloaca		* grows rostro caudally cervical -> cloaca
	* [[Carnegie stage 10\|Human E22]] nephrogenic mesenchyme differentiates to form pronephroi not functional in mammals, degenerates rapidly		* [[Carnegie stage 10\|Human E22]] nephrogenic mesenchyme differentiates to form pronephroi not functional in mammals, degenerates rapidly
Line 160:		Line 160:
	[[File:Stage 13 kidney sections 2.jpg\|thumb\|Stage 13 mesonephros]]		[[File:Stage 13 kidney sections 2.jpg\|thumb\|Stage 13 mesonephros]]
	[[File:Stage22 mesonephros.jpg\|thumb\|Stage 22 mesonephros]]		[[File:Stage22 mesonephros.jpg\|thumb\|Stage 22 mesonephros]]
	* [[Carnegie stage 11\|Human E24]], Mouse E9.5 caudal to pronephros		* [[Carnegie stage 11\|Human E24]], Mouse {{ME9.5}} caudal to pronephros
	* forms by induction from pronephros		* forms by induction from pronephros
	* '''pronephric duct''' now becomes '''mesonephric duct''' (also called Wolffian Duct)		* '''pronephric duct''' now becomes '''mesonephric duct''' (also called Wolffian Duct)

2018-08-27T22:04:13Z

Cloaca

← Older revision		Revision as of 08:04, 28 August 2018
Line 324:		Line 324:
	==Cloaca==		==Cloaca==
	{\|		{\|
			\|
	* Endoderm (yellow)		* Endoderm (yellow)
	* hindgut region ending at the cloacal membrane		* hindgut region ending at the cloacal membrane
Line 334:		Line 335:

	This cartoon sequence shows the changing organisation of the endoderm from week 3 to 5.		This cartoon sequence shows the changing organisation of the endoderm from week 3 to 5.
	\|

	\|}		\|}

2018-08-27T22:03:43Z

Cloaca

← Older revision		Revision as of 08:03, 28 August 2018
Line 324:		Line 324:
	==Cloaca==		==Cloaca==
	{\|		{\|
	~~\| [[File:Endoderm_cartoon.jpg\|File:Endoderm development]]~~

	~~This cartoon sequence shows the changing organisation of the endoderm from week 3 to 5.~~
	\|
	* Endoderm (yellow)		* Endoderm (yellow)
	* hindgut region ending at the cloacal membrane		* hindgut region ending at the cloacal membrane
Line 333:		Line 329:
	** ventral - common urogenital sinus		** ventral - common urogenital sinus
	** dorsal - rectum		** dorsal - rectum
	\|}
	~~{\| border='0px'~~

	\|-		{{Renal overview movie}}{{Urogenital_septum_movie}}
	\| {{Renal overview movie}}		\| [[File:Endoderm_cartoon.jpg\|File:Endoderm development]]
	\| {{Urogenital_septum_movie}}
			This cartoon sequence shows the changing organisation of the endoderm from week 3 to 5.
			\|

	\|}		\|}

2018-08-27T22:02:59Z

Cloaca

← Older revision		Revision as of 08:02, 28 August 2018
Line 323:		Line 323:

	==Cloaca==		==Cloaca==
	[[File:Endoderm_cartoon.jpg\|File:Endoderm development]]		{\|
			\| [[File:Endoderm_cartoon.jpg\|File:Endoderm development]]

	This cartoon sequence shows the changing organisation of the endoderm from week 3 to 5.		This cartoon sequence shows the changing organisation of the endoderm from week 3 to 5.
			\|
	* Endoderm (yellow)		* Endoderm (yellow)
	* hindgut region ending at the cloacal membrane		* hindgut region ending at the cloacal membrane
Line 332:		Line 333:
	** ventral - common urogenital sinus		** ventral - common urogenital sinus
	** dorsal - rectum		** dorsal - rectum
			\|}
	{\| border='0px'		{\| border='0px'

2018-08-27T22:00:55Z

Endocrine Kidney

← Older revision		Revision as of 08:00, 28 August 2018
Line 314:		Line 314:
	* Renin - Increase Angiotensin-aldosterone system		* Renin - Increase Angiotensin-aldosterone system
	* Prostaglandins - decrease Na+ reabsorption		* Prostaglandins - decrease Na+ reabsorption
	* Erythropoietin - ~~Increase Erythrocyte~~ (rbc) production		* Erythropoietin - (Epo) increase erythrocyte (rbc) production
	* 1,25 (OH)2 vitamin D - Calcium homeostasis		* 1,25 (OH)2 vitamin D - Calcium homeostasis
	* Prekallikreins - (plasma protein inactive precursor of kallikrein) Increase kinin production (altered vascular permeability)		* Prekallikreins - (plasma protein inactive precursor of kallikrein)
			** Increase kinin production (altered vascular permeability)

2018-08-27T21:57:28Z

Urinary Bladder

← Older revision		Revision as of 07:57, 28 August 2018
Line 352:		Line 352:
	* early origins of the bladder at the superior end of the common '''urogenital sinus'''		* early origins of the bladder at the superior end of the common '''urogenital sinus'''
	* open inferiorly to the '''cloaca''' and superiorly to the '''allantois'''		* open inferiorly to the '''cloaca''' and superiorly to the '''allantois'''
	* Septation of the claoca divides ~~the~~		* Septation of the claoca divides
	** anterior region to the primordial bladder component		** '''anterior region''' to the primordial '''bladder''' component
	** posterior region to the primordial rectal component		** posterior region to the primordial rectal component
	* two '''ureters''' form from the ureteric bud		* two '''ureters''' form from the ureteric bud

2018-08-27T21:54:01Z

Background

← Older revision		Revision as of 07:54, 28 August 2018
Line 71:		Line 71:
	\|}		\|}
	== Background==		== Background==
	* {{mesoderm}} - then {{intermediate mesoderm}}		* {{mesoderm}} - then intermediate mesoderm
	* {{Endoderm}} - cloaca, urogenital sinus, hindgut, allantois		* {{Endoderm}} - cloaca, urogenital sinus, hindgut, allantois
	* Vascular Development		* Vascular Development

2018-08-27T21:53:29Z

Background

← Older revision		Revision as of 07:53, 28 August 2018
Line 71:		Line 71:
	\|}		\|}
	== Background==		== Background==
	* ~~Mesoderm~~ - then intermediate mesoderm		* {{mesoderm}} - then {{intermediate mesoderm}}
	* Endoderm - cloaca, urogenital sinus, ~~handgun~~, allantois		* {{Endoderm}} - cloaca, urogenital sinus, hindgut, allantois
	* Vascular Development		* Vascular Development
	* Gastrointestional		* Gastrointestional
	* Cloacal development		* Cloacal development
	* Endocrine - covered in future lecture/lab		* {{Endocrine}} - covered in future lecture/lab

	==Renal Anatomy==		==Renal Anatomy==