Lecture - Placenta Development - Revision history

Z8600021: /* Maternal Placenta */

2018-08-20T23:49:30Z

Maternal Placenta

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	{\|		{\|
	\| '''Decidualization''' ~~- process~~ of endometrial stromal cells (fibroblast-like) change in morphology (polygonal cells) and protein expression and secretion (specific decidual proteins: prolactin, insulin-like growth factor binding protein-1, tissue factor, interleukin-15, and VEGF).		\| '''Decidualization'''

			Process of endometrial stromal cells (fibroblast-like) change in morphology (polygonal cells) and protein expression and secretion (specific decidual proteins: prolactin, insulin-like growth factor binding protein-1, tissue factor, interleukin-15, and VEGF).
	# Estrogen and progesterone - receptive phase, luminal and glandular epithelial cells change in preparation for blastocyst adplantation.		# Estrogen and progesterone - receptive phase, luminal and glandular epithelial cells change in preparation for blastocyst adplantation.
	# Human Chorionic gonadotropin - luminal epithelium endoreplication leading to epithelial plaque formation.		# Human Chorionic gonadotropin - luminal epithelium endoreplication leading to epithelial plaque formation.

Z8600021: /* Maternal Placenta */

2018-08-20T23:49:04Z

Maternal Placenta

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	Fibrinoid layer (Nitabuch's layer) is thought to act to prevent excessively deep implantation.		Fibrinoid layer (Nitabuch's layer) is thought to act to prevent excessively deep implantation.

	'''Decidualization''' - process of endometrial stromal cells (fibroblast-like) change in morphology (polygonal cells) and protein expression and secretion (specific decidual proteins: prolactin, insulin-like growth factor binding protein-1, tissue factor, interleukin-15, and VEGF).		{\|
			\| '''Decidualization''' - process of endometrial stromal cells (fibroblast-like) change in morphology (polygonal cells) and protein expression and secretion (specific decidual proteins: prolactin, insulin-like growth factor binding protein-1, tissue factor, interleukin-15, and VEGF).
	# Estrogen and progesterone - receptive phase, luminal and glandular epithelial cells change in preparation for blastocyst adplantation.		# Estrogen and progesterone - receptive phase, luminal and glandular epithelial cells change in preparation for blastocyst adplantation.
	# Human Chorionic gonadotropin - luminal epithelium endoreplication leading to epithelial plaque formation.		# Human Chorionic gonadotropin - luminal epithelium endoreplication leading to epithelial plaque formation.
	# Human Chorionic gonadotropin - trophoblast invasion and decidualization of human stromal fibroblasts.		# Human Chorionic gonadotropin - trophoblast invasion and decidualization of human stromal fibroblasts.
			\| [[File:Placenta anchoring villi.jpg\|500px]]
			\|}

	'''Artery Dilatation''' - due to extravillous trophoblast cells invading uterine wall and maternal spiral arteries replacing both smooth muscle with fibrinoid material and part of vessel endothelium. There is also a proliferation of maternal blood vessels.		'''Artery Dilatation''' - due to extravillous trophoblast cells invading uterine wall and maternal spiral arteries replacing both smooth muscle with fibrinoid material and part of vessel endothelium. There is also a proliferation of maternal blood vessels.

Z8600021: /* Chorionoic Villi Trimester Development */

2018-08-20T23:31:09Z

Chorionoic Villi Trimester Development

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	* '''Trimester 3''' - mature intermediate villi develop during the last trimester, produce numerous terminal villi.		* '''Trimester 3''' - mature intermediate villi develop during the last trimester, produce numerous terminal villi.
	** Terminal villi are not active outgrowths caused by trophoblast proliferation, passive protrusions induced by capillary coiling due to excessive longitudinal growth of the fetal capillaries within the mature intermediate villi.		** Terminal villi are not active outgrowths caused by trophoblast proliferation, passive protrusions induced by capillary coiling due to excessive longitudinal growth of the fetal capillaries within the mature intermediate villi.
	** Capillary bed arrangement in the terminal villi can vary from simple U-like loops to branched network, due to capillary elongation and sprouting.(Data from ~~PMID~~ 2327595)		** Capillary bed arrangement in the terminal villi can vary from simple U-like loops to branched network, due to capillary elongation and sprouting. (Data from{{#pmid:2327595\|PMID2327595}})


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	\| [[File:Spiral artery trophoblast plug cartoon1.jpg\|300px]]		\| [[File:Spiral artery trophoblast plug cartoon1.jpg\|300px]]

	First trimester spiral artery trophoblast plug.~~<ref name=~~PMID27510415~~><pubmed>27510415</pubmed></ref>~~		First trimester spiral artery trophoblast plug.{{#pmid:27510415\|PMID27510415}}
	\| [[File:Gray0039.jpg\|500px\|alt=Scheme of placental circulation]]		\| [[File:Gray0039.jpg\|500px\|alt=Scheme of placental circulation]]
	\|}		\|}

Z8600021: /* Placental Types */

2018-08-20T23:29:48Z

Placental Types

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	==Placental Types==		==Placental Types==
	[[File:Mouse_placenta_01.jpg\|thumb\|Mouse placenta]]		[[File:Mouse_placenta_01.jpg\|thumb\|Mouse placenta]]
	* Discoid in humans, ~~mice~~, insectivores, ~~rabbits~~, ~~rats~~, and monkeys.		* Discoid in humans, {{mouse}}, insectivores, {{rabbit}}, {{rat}}, and monkeys.
	* Zonary in ~~dogs~~, ~~cats~~, bears and seals.		* Zonary in {{dog}}, {{cat}}, bears and seals.
	* Cotyledenary in ~~cows~~, deer, goat, and giraffe.		* Cotyledenary in {{cow}}, deer, goat, and giraffe.
	* Diffuse in ~~horses~~, ~~pigs~~, camels, lemurs, opossums, ~~kangaroos~~, and whales		* Diffuse in {{horse}}, {{pig}}, camels, lemurs, opossums, {{kangaroo}}, and whales



	:'''Links:''' [http://placentation.ucsd.edu/homefs.html Comparative Placentation]		:'''Links:''' [http://placentation.ucsd.edu/homefs.html Comparative Placentation]


	===Chorionoic Villi Trimester Development===		===Chorionoic Villi Trimester Development===

Z8600021 at 23:27, 20 August 2018

2018-08-20T23:27:49Z

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	The placenta and placental blood at birth has recently been seen as a new source for [[Stem Cells\|stem cells]] in bone marrow replacement therapy in many diseases. The topic of stem cells will be covered later in this current course.		The placenta and placental blood at birth has recently been seen as a new source for [[Stem Cells\|stem cells]] in bone marrow replacement therapy in many diseases. The topic of stem cells will be covered later in this current course.


			[[Media:ANAT2341Lecture 2018 - Placenta Development.pdf\|2018 Lecture - Print PDF]]


	== Lecture Objectives ==		== Lecture Objectives ==

Z8600021 at 00:58, 20 August 2018

2018-08-20T00:58:01Z

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	The placenta and placental blood at birth has recently been seen as a new source for [[Stem Cells\|stem cells]] in bone marrow replacement therapy in many diseases. The topic of stem cells will be covered later in this current course.		The placenta and placental blood at birth has recently been seen as a new source for [[Stem Cells\|stem cells]] in bone marrow replacement therapy in many diseases. The topic of stem cells will be covered later in this current course.

	~~{\| class="wikitable mw-collapsible mw-collapsed"~~
	~~! 2016 Lecture Video Recording  ~~
	\|-
	~~\| This 2016 lecture video recording is similar in content to the current 2017 online lecture.~~
	\|-
	~~\| <html5media height="600" width="820">File:2016Lecture-Placenta.mp4</html5media><br>~~
	~~[[Media:2016Lecture-Placenta.mp4\|'''Click Here''' to play on mobile device]] [[File:Moviebar-icons.jpg\|200px\|right]]~~
	\|}

	== Lecture Objectives ==		== Lecture Objectives ==
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	\|		\|
	{{Placenta Links}}		{{Placenta Links}}
	* Lecture Archive: [[Media:Lecture_2016_-_Pacenta Development.pdf\|2016 PDF]] [https://embryology.med.unsw.edu.au/embryology/index.php?title=Lecture_-_Placenta_Development&oldid=243337 2015] \| [[Media:2015ANAT2341_Lecture_8_-_Placenta_Development.pdf\|2015 PDF]][https://embryology.med.unsw.edu.au/embryology/index.php?title=Lecture_-_Placenta_Development&oldid=143128 2014 lecture] \| [[Media:ANAT2341_Lecture_8_-_2014_Placenta_Development.pdf\|2014 PDF]]		* Lecture Archive: [https://embryology.med.unsw.edu.au/embryology/index.php?title=Lecture_-_Placenta_Development&oldid=300827 2017] \| [[Media:Lecture_2016_-_Pacenta Development.pdf\|2016 PDF]] [https://embryology.med.unsw.edu.au/embryology/index.php?title=Lecture_-_Placenta_Development&oldid=243337 2015] \| [[Media:2015ANAT2341_Lecture_8_-_Placenta_Development.pdf\|2015 PDF]][https://embryology.med.unsw.edu.au/embryology/index.php?title=Lecture_-_Placenta_Development&oldid=143128 2014 lecture] \| [[Media:ANAT2341_Lecture_8_-_2014_Placenta_Development.pdf\|2014 PDF]]
	\|-		\|-
	\| {{MPT2015cover_citation}}		\| {{MPT2015cover_citation}}
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	\| valign="bottom"\|{{Stage 13 MRI movie 1}}		\| valign="bottom"\|{{Stage 13 MRI movie 1}}
	\|}		\|}
			{\| class="wikitable mw-collapsible mw-collapsed"
			! 2016 Lecture Video Recording
			\|-
			\| This 2016 lecture video recording may differ from the the current 2018 online lecture.
			\|-
			\| <html5media height="600" width="820">File:2016Lecture-Placenta.mp4</html5media><br>
			[[Media:2016Lecture-Placenta.mp4\|'''Click Here''' to play on mobile device]] [[File:Moviebar-icons.jpg\|200px\|right]]
			\|}
	== Nutrition ==		== Nutrition ==
	* Histiotrophic ~~nutrition~~ - describes ~~early placental development and~~ the ~~form of~~ intital transfer of nutrition from maternal to embryo.		* '''Histiotrophic''' - describes the intital transfer of nutrition from maternal to embryo.
	* Haemotrophic ~~nutrition~~ - describes the later blood-borne nutrition.		** occurs before implantation and during early implantation mainly from uterine glands.
			* '''Haemotrophic''' - describes the later blood-borne nutrition.
			** occurs in the embryonic and fetal period after placenta development.
	==Fetal Membranes==		==Fetal Membranes==
	<gallery>		<gallery>
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	* [http://courseweb.edteched.uottawa.ca/medicine-histology/English/Reproduction/Placenta/Default.htm University of Ottawa - Histology - Placenta]		* [http://courseweb.edteched.uottawa.ca/medicine-histology/English/Reproduction/Placenta/Default.htm University of Ottawa - Histology - Placenta]
	* Virtual Microscopy Histology		* Virtual Microscopy Histology


	== Placenta Terms ==		== Placenta Terms ==
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	{{~~2017ANAT2341 footer~~}}		{{2018ANAT2341}}


	[[Category:Placenta]]		[[Category:Placenta]]

Z8600021 at 03:07, 17 August 2017

2017-08-17T03:07:54Z

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	\| {{SBBF2015cover_citation}}		\| {{SBBF2015cover_citation}}
	\| The following chapter links only work with a UNSW [http://er.library.unsw.edu.au/er/cgi-bin/eraccess.cgi?url=http://www.unsw.eblib.com.wwwproxy0.library.unsw.edu.au/patron/FullRecord.aspx?p=2074524 UNSW Library subscription]		\| The following chapter links only work with a UNSW [http://er.library.unsw.edu.au/er/cgi-bin/eraccess.cgi?url=http://www.unsw.eblib.com.wwwproxy0.library.unsw.edu.au/patron/FullRecord.aspx?p=2074524 UNSW Library subscription]
	* [http://~~www~~.~~unsw.eblib~~.com.~~wwwproxy0~~.library.unsw.edu.au/~~patron~~/~~Read~~.~~aspx~~?p=2074524&pg=61 Second Week: Becoming Bilaminar and Fully Implanting]		* [http://ebookcentral.proquest.com.wwwproxy1.library.unsw.edu.au/lib/unsw/reader.action?docID=2074524&ppg=61 Second Week: Becoming Bilaminar and Fully Implanting]
	* [http://~~www.unsw~~.~~eblib~~.com.~~wwwproxy0~~.library.unsw.edu.au/~~patron~~/~~Read~~.~~aspx~~?p=2074524&pg=322 Development of the Vasculature]		* [http://ebookcentral.proquest.com.wwwproxy1.library.unsw.edu.au/lib/unsw/reader.action?docID=2074524&ppg=322 Development of the Vasculature]
	\|}		\|}
	{\| class="wikitable mw-collapsible mw-collapsed"		{\| class="wikitable mw-collapsible mw-collapsed"

Z8600021: /* Lecture Resources */

2017-08-17T03:04:03Z

Lecture Resources

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	\| {{MPT2015cover_citation}}		\| {{MPT2015cover_citation}}
	\| The following chapter links only work with a UNSW connection.		\| The following chapter links only work with a UNSW connection.
	* [http://~~www.unsw~~.~~eblib~~.com.~~wwwproxy0~~.library.unsw.edu.au/~~patron~~/~~Read~~.~~aspx~~?p=~~1430154~~&pg=~~131 Chapter 7 -~~ Placenta and Fetal Membranes]		* Chapter 7 - [http://ebookcentral.proquest.com.wwwproxy1.library.unsw.edu.au/lib/unsw/reader.action?docID=2074364&ppg=155 Placenta and Fetal Membranes]
	\|-		\|-
	\| {{SBBF2015cover_citation}}		\| {{SBBF2015cover_citation}}

Z8600021 at 00:48, 17 August 2017

2017-08-17T00:48:50Z

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	{\|		{\|
	\| [[File:Gray0034.jpg\|~~300px~~]]		\| [[File:Gray0034.jpg\|400px]]
	\| [[File:Bailey494.jpg\|~~300px~~]]		\| [[File:Bailey494.jpg\|400px]]
	\|}		\|}

Z8600021 at 23:43, 13 August 2017

2017-08-13T23:43:37Z

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	This lecture is an introduction to the development and functions of the placenta.		This lecture is an introduction to the development and functions of the placenta.

	~~{{2017ANAT2341draftnotice}}~~

	The placenta (Greek, ''plakuos'' = flat cake) named on the basis of this organs appearance. The placenta a mateno-fetal organ which begins developing at implantation of the blastocyst and is delivered with the fetus at birth. Only recently have we begun to understand the many different functions this organ carries out in addition to its role in embryonic nutrition.		The placenta (Greek, ''plakuos'' = flat cake) named on the basis of this organs appearance. The placenta a mateno-fetal organ which begins developing at implantation of the blastocyst and is delivered with the fetus at birth. Only recently have we begun to understand the many different functions this organ carries out in addition to its role in embryonic nutrition.