Lecture - Neural Crest Development - Revision history

Z8600021: /* Neuroblastoma */

2018-08-27T01:52:29Z

Neuroblastoma

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	Neuroblastoma is the most common childhood cancer diagnosed before the age of 1 year, and accounts for 10 to 15% of all cancer deaths in children arising initially from the {{adrenal}} or other tissues.		Neuroblastoma is the most common childhood cancer diagnosed before the age of 1 year, and accounts for 10 to 15% of all cancer deaths in children arising initially from the {{adrenal}} or other tissues.

	[[File:Childhood cancer survival rates.jpg\|~~thumb\|~~Childhood cancer survival rates]]		[[File:Childhood cancer survival rates.jpg\|400px]]

			Childhood cancer survival rates

Z8600021: /* Neural Crest - Peripheral Nervous System */

2018-08-27T01:51:18Z

Neural Crest - Peripheral Nervous System

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	==Neural Crest - Peripheral Nervous System==		==Neural Crest - Peripheral Nervous System==
	{\|		{\|
	\|		\| width=300px\|
	* peripheral nervous system		* peripheral nervous system
	* dorsal root ganglia (sensory N)		* dorsal root ganglia (sensory N)

Z8600021: /* Early Development and Neural Derivatives */

2018-08-27T01:34:03Z

Early Development and Neural Derivatives

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	* cranial expansion of neural tube - central nervous system		* cranial expansion of neural tube - central nervous system
	* caudal remainder of neural tube - spinal cord		* caudal remainder of neural tube - spinal cord


	Neural Crest - contributes both neural and non-neural cells		Neural Crest - contributes both neural and non-neural cells
	* dorsal root ganglia		* dorsal root ganglia
	* parasympathetic / sympathetic ganglia.		* parasympathetic / sympathetic ganglia.
			* enteric ganglia

	==Neural Crest Origin==		==Neural Crest Origin==

Z8600021 at 00:09, 27 August 2018

2018-08-27T00:09:44Z

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	{{Header}}		{{Header}}
	== Introduction ==		== Introduction ==
	[[File:Stage11 sem21.jpg\|thumb\|300px\|Human embryo neural crest cells ([[Week 4]], [[Carnegie stage ~~11\|stage 11]]~~)]]		[[File:Stage11 sem21.jpg\|thumb\|300px\|Human embryo neural crest cells ([[Week 4]], Carnegie stage {{CS11}})]]
	[[File:Human Stage14 neural02.jpg\|thumb\|300px\|Human embryo neural ([[Week 5]], [[Carnegie stage 14\|stage 14]])]]		[[File:Human Stage14 neural02.jpg\|thumb\|300px\|Human embryo neural ([[Week 5]], [[Carnegie stage 14\|stage 14]])]]
	The neural crest are bilaterally paired strips of cells arising in the ectoderm at the margins of the neural tube. These cells migrate to many different locations and differentiate into many cell types within the embryo. This means that many different systems (neural, skin, teeth, head, face, heart, endocrine, gastrointestinal tract) will also have a contribution fron the neural crest cells.		The neural crest are bilaterally paired strips of cells arising in the ectoderm at the margins of the neural tube. These cells migrate to many different locations and differentiate into many cell types within the embryo. This means that many different systems (neural, skin, teeth, head, face, heart, endocrine, gastrointestinal tract) will also have a contribution fron the neural crest cells.
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	==Lecture Objectives==		==Lecture Objectives==
	[[File:Carnegie stage 13 caudal trunk.jpg\|thumb\|Human Embryo (Carnegie stage 13) caudal trunk~~<ref><pubmed>~~18689800~~</pubmed>~~\| ~~[http://hmg.oxfordjournals.org/cgi/content/full/17/21/3411 Hum Mol Genet.]</ref>~~]]		[[File:Carnegie stage 13 caudal trunk.jpg\|thumb\|Human Embryo (Carnegie stage 13) caudal trunk{{#pmid:18689800\|PMID18689800}}]]

	* Understand the structures derived from ectoderm.		* Understand the structures derived from ectoderm.
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	[[File:Neural crest contribution.jpg\|600px]]		[[File:Neural crest contribution.jpg\|600px]]

	Neural crest contribution~~<ref><pubmed>~~23817048~~</pubmed></ref>~~		Neural crest contribution{{#pmid:23817048\|PMID23817048}}

	{{Neural Crest table}}		{{Neural Crest table}}
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	[[File:Cardiac_Neural_Crest_Migration.jpg\|300px]]		[[File:Cardiac_Neural_Crest_Migration.jpg\|300px]]

	[[File:Human neural crest cell migration-in vitro.jpg\|thumb\|Human neural crest cell migration (in vitro)~~<ref><pubmed>~~18689800~~</pubmed>~~\| ~~[http://hmg.oxfordjournals.org/cgi/content/full/17/21/3411 Hum Mol Genet.]</ref>~~]]		[[File:Human neural crest cell migration-in vitro.jpg\|thumb\|Human neural crest cell migration (in vitro){{#pmid:18689800\|PMID18689800}}]]
	[http://www.ncbi.nlm.nih.gov/books/bv.fcgi?&rid=dbio.figgrp.3118 Figure 13.2. Neural crest cell migration in the trunk of the chick embryo]		[http://www.ncbi.nlm.nih.gov/books/bv.fcgi?&rid=dbio.figgrp.3118 Figure 13.2. Neural crest cell migration in the trunk of the chick embryo]
	* Neural crest at the level of the body have two general migration pathways, defined by the position of the somite		* Neural crest at the level of the body have two general migration pathways, defined by the position of the somite
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	\| width=205px\|[[File:Neural crest cell enteric sorting.jpg\|200px]]		\| width=205px\|[[File:Neural crest cell enteric sorting.jpg\|200px]]

	Enteric neuron (red) and glia (blue) aggregation.~~<ref><pubmed>~~26064478 ~~</pubmed></ref>~~		Enteric neuron (red) and glia (blue) aggregation.{{#pmid:26064478\|PMID26064478}}
	\|}		\|}
	:'''Links:''' [[Neural_Crest_-_Enteric_Nervous_System\|Enteric Nervous System]] \| [http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=eurekah&part=A63004&rendertype=figure&id=A63009 Figure 1. Mouse E10 embryo origins of NCCs for GIT]		:'''Links:''' [[Neural_Crest_-_Enteric_Nervous_System\|Enteric Nervous System]] \| [http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=eurekah&part=A63004&rendertype=figure&id=A63009 Figure 1. Mouse E10 embryo origins of NCCs for GIT]
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	(TCS) A genetic developmental abnormality results from autosomal dominant mutations of the gene TCOF1 encoding the protein Treacle, identified in [http://www.ncbi.nlm.nih.gov/pubmed/8563749 2006]. The syndrome is characterized by hypoplasia of the facial bones, cleft palate, and middle and external ear defects. These defects may relate to the effects on neural crest migration. (More? [[Neural Crest Development]] \| [http://www.ncbi.nlm.nih.gov/omim/606847 OMIM - TCOF1] \| [http://www.ncbi.nlm.nih.gov/pubmed/8563749 PMID: 8563749])		(TCS) A genetic developmental abnormality results from autosomal dominant mutations of the gene TCOF1 encoding the protein Treacle, identified in [http://www.ncbi.nlm.nih.gov/pubmed/8563749 2006]. The syndrome is characterized by hypoplasia of the facial bones, cleft palate, and middle and external ear defects. These defects may relate to the effects on neural crest migration. (More? [[Neural Crest Development]] \| [http://www.ncbi.nlm.nih.gov/omim/606847 OMIM - TCOF1] \| [http://www.ncbi.nlm.nih.gov/pubmed/8563749 PMID: 8563749])


	== References ==		== References ==

Z8600021 at 00:07, 27 August 2018

2018-08-27T00:07:03Z

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	The term "neural crest was first used in {{Ref-Marshall1879}}.		The term "neural crest was first used in {{Ref-Marshall1879}}.


			[[Media:ANAT2341Lecture 2018 - Neural Crest Development.pdf\|2018 Lecture - Print PDF]]

Z8600021: /* Neuroblastoma */

2018-08-26T23:48:03Z

Neuroblastoma

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	===Neuroblastoma===		===Neuroblastoma===
	[[File:Neuroblastoma.jpg\|thumb\|Neuroblastoma]]		[[File:Neuroblastoma.jpg\|thumb\|Neuroblastoma]]
	Neuroblastoma is the most common childhood cancer diagnosed before the age of 1 year, and accounts for 10 to 15% of all cancer deaths in children.		Neuroblastoma is the most common childhood cancer diagnosed before the age of 1 year, and accounts for 10 to 15% of all cancer deaths in children arising initially from the {{adrenal}} or other tissues.

	[[File:Childhood cancer survival rates.jpg\|thumb\|Childhood cancer survival rates]]		[[File:Childhood cancer survival rates.jpg\|thumb\|Childhood cancer survival rates]]

	[http://omim.org/entry/256700 OMIM - Neuroblastoma]
			[[Neural_Crest_System_-_Abnormalities#Neuroblastoma\|Neuroblastoma]] \| [http://omim.org/entry/256700 OMIM - Neuroblastoma]

	===Digeorge Syndrome (DGS)===		===Digeorge Syndrome (DGS)===

Z8600021 at 23:44, 26 August 2018

2018-08-26T23:44:26Z

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 The term "neural crest was first used in {{Ref-Marshall1879}}.
 ==Lecture Objectives==
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 |}
 ==Neural Crest Migration in the Head==
 {| border='0px'

Z8600021 at 02:29, 24 August 2018

2018-08-24T02:29:29Z

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	\|		\|
	{{Neural Crest Links}}		{{Neural Crest Links}}
	* Lecture Archive: [https://embryology.med.unsw.edu.au/embryology/index.php?title=Lecture_-_Neural_Crest_Development&oldid=198021 2015] \| [[Media:2015ANAT2341_Lecture_12_-_Neural Crest Development.pdf\|2015 PDF]] \| [https://embryology.med.unsw.edu.au/embryology/index.php?title=Lecture_-_Neural_Crest_Development&oldid=143785 2014] \| [[Media:ANAT2341_Lecture_12_-_2014_Neural_Crest_Development.pdf\|2014 PDF]]		* Lecture Archive: [https://embryology.med.unsw.edu.au/embryology/index.php?title=Lecture_-_Neural_Crest_Development&oldid=310822 2017] \| [https://embryology.med.unsw.edu.au/embryology/index.php?title=Lecture_-_Neural_Crest_Development&oldid=198021 2015] \| [[Media:2015ANAT2341_Lecture_12_-_Neural Crest Development.pdf\|2015 PDF]] \| [https://embryology.med.unsw.edu.au/embryology/index.php?title=Lecture_-_Neural_Crest_Development&oldid=143785 2014] \| [[Media:ANAT2341_Lecture_12_-_2014_Neural_Crest_Development.pdf\|2014 PDF]]
	\|-		\|-
	\| [[File:The Developing Human, 10th edn.jpg\|90px]]		\| [[File:The Developing Human, 10th edn.jpg\|90px]]
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	{{~~2017ANAT2341 footer~~}}		{{2018ANAT2341}}
	[[Category:Neural Crest]]		[[Category:Neural Crest]]

Z8600021 at 02:25, 10 October 2017

2017-10-10T02:25:00Z

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	The neural crest are bilaterally paired strips of cells arising in the ectoderm at the margins of the neural tube. These cells migrate to many different locations and differentiate into many cell types within the embryo. This means that many different systems (neural, skin, teeth, head, face, heart, endocrine, gastrointestinal tract) will also have a contribution fron the neural crest cells.		The neural crest are bilaterally paired strips of cells arising in the ectoderm at the margins of the neural tube. These cells migrate to many different locations and differentiate into many cell types within the embryo. This means that many different systems (neural, skin, teeth, head, face, heart, endocrine, gastrointestinal tract) will also have a contribution fron the neural crest cells.

	~~{{2017ANAT2341draftnotice}}~~

	In the body region, neural crest cells also contribute the peripheral nervous system (both neurons and glia) consisting of sensory ganglia (dorsal root ganglia), sympathetic and parasympathetic ganglia and neural plexuses within specific tissues/organs.		In the body region, neural crest cells also contribute the peripheral nervous system (both neurons and glia) consisting of sensory ganglia (dorsal root ganglia), sympathetic and parasympathetic ganglia and neural plexuses within specific tissues/organs.

Z8600021: /* Introduction */

2017-09-10T02:23:04Z

Introduction

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	The term "neural crest was first used in {{Ref-Marshall1879}}.		The term "neural crest was first used in {{Ref-Marshall1879}}.

	~~There~~ is ~~currently no archive recording for this~~ lecture.
			{\| class="wikitable mw-collapsible mw-collapsed"
			! 2016 Lecture Video Recording
			\|-
			\| This 2016 lecture video recording is similar in content to the current 2017 online lecture.

			<html5media height="600" width="800">File:2016Lecture-Neural Crest.mp4</html5media>

			Click to play new window - [[Media:2016Lecture-Neural Crest.mp4\|'''2016 Lecture Video''']] (48 MB)
			\|}

	==Lecture Objectives==		==Lecture Objectives==