Lecture - Gastrointestinal Development - Revision history

Z8600021 at 03:12, 6 August 2018

2018-08-06T03:12:32Z

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	[[File:Normal intestinal rotation cartoon.jpg\|500px]]		[[File:Normal intestinal rotation cartoon.jpg\|500px]]

	Normal intestinal rotation (note these are gestational age {{GA}} weeks)~~<ref><pubmed>~~20549505~~</pubmed>~~\| ~~[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908440 PMC2908440]</ref>~~		Normal intestinal rotation (note these are gestational age {{GA}} weeks){{#pmid:20549505\|PMID20549505}}

	===Hindgut===		===Hindgut===
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	* Incomplete recanalization resulting in parallel lumens, this is really a specialized form of stenosis.		* Incomplete recanalization resulting in parallel lumens, this is really a specialized form of stenosis.
	\| [[File:Gastrointestinal tract duplication sites.jpg\|300px\|Gastrointestinal tract duplication sites based upon 78 clinical studies.~~<ref><pubmed>~~718292~~</pubmed></ref>~~]]		\| [[File:Gastrointestinal tract duplication sites.jpg\|300px\|Gastrointestinal tract duplication sites based upon 78 clinical studies.{{#pmid:718292\|PMID718292]]
	\|}		\|}

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	'''Links:''' [[Gastrointestinal Tract - Abnormalities]]		'''Links:''' [[Gastrointestinal Tract - Abnormalities]]


			==References==
	<references/>		<references/>

	== Terms ==		== Terms ==
			Expand the table below to see GIT related terms.

	{{GIT terms}}		{{GIT terms}}

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	* '''Omphalocele''' - appears similar to gastroschisis, herniation of the bowel, liver and other organs into the intact umbilical cord, the tissues being '''covered by membranes''' unless the latter are ruptured.		* '''Omphalocele''' - appears similar to gastroschisis, herniation of the bowel, liver and other organs into the intact umbilical cord, the tissues being '''covered by membranes''' unless the latter are ruptured.

	\| ~~[[File:Gastroschisis_01.jpg\|200px\|link=Ultrasound_-_~~ Gastroschisis ~~01]]~~		\| {{Ultrasound Gastroschisis}}
	\|-		\|-
	\|
	~~\| [[Ultrasound_-_ Gastroschisis 01\|Gastroschisis]]~~
	\|}		\|}

Z8600021 at 01:40, 6 August 2018

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	\| [[File:Stage 22 image 087.jpg\|thumb\|300px\|Spleen week 8 stage 22 embryo]]		\| [[File:Stage 22 image 087.jpg\|thumb\|300px\|Spleen week 8 stage 22 embryo]]
	\|}		\|}

			==Enteric Nervous System==
			Topic covered in the neural crest lecture. Table below summarises the two major neural plexuses.


			{{GIT plexus table}}

	== Gastrointestinal Tract Abnormalities ==		== Gastrointestinal Tract Abnormalities ==

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	\|-		\|-
	\|		\|
	{{~~Template:~~USA_Selected_defect_table_2006}}		{{USA_Selected_defect_table_2006}}
	\|}		\|}
	===Lumen Abnormalities===		===Lumen Abnormalities===

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	\|}		\|}

	~~Endoderm~~ and splanchnic mesoderm at the level of the transverse septum (week 4)		{{Liver}} contributions from endoderm and splanchnic mesoderm at the level of the transverse septum (week 4)
	* Stage 11 - hepatic diverticulum development		* Stage 11 - hepatic diverticulum development
	* Stage 12 - cell differentiation, septum transversum forming liver stroma, hepatic diverticulum forming hepatic trabeculae		* Stage 12 - cell differentiation, septum transversum forming liver stroma, hepatic diverticulum forming hepatic trabeculae
	* Stage 13 - epithelial cord proliferation enmeshing stromal capillaries		* Stage 13 - epithelial cord proliferation enmeshing stromal capillaries

	The liver initially occupies the entire anterior body. All blood vessels enter the liver (placental, vitelline) and leave to enter the heart.		The {{liver}} initially occupies the entire anterior body. All blood vessels enter the liver (placental, vitelline) and leave to enter the heart.

	===Stomach===		===Stomach===

Z8600021 at 01:29, 6 August 2018

2018-08-06T01:29:09Z

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	Note that we will be returning in the laboratory and later (head, endocrine, neural crest) to discuss the gastrointestinal tract, associated organs and physical growth changes.		Note that we will be returning in the laboratory and later (head, endocrine, neural crest) to discuss the gastrointestinal tract, associated organs and physical growth changes.



			[[Media:ANAT2341Lecture 2018 - Endoderm.pdf\|2018 Lecture - Print PDF]]

Z8600021 at 05:45, 2 August 2018

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	\|}		\|}
	{\| class="wikitable mw-collapsible mw-collapsed"		{\| class="wikitable mw-collapsible mw-collapsed"
	! References		! References
	\|-		\|-
	\| {{Embryo logocitation}}		\| {{Embryo logocitation}}
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	== Germ Layer Contributions ==		== Germ Layer Contributions ==

	* '''~~Endoderm~~''' - epithelium and associated glands.		* '''{{endoderm}}''' - epithelium and associated glands.

	* '''~~Mesoderm~~''' (splanchnic) - mesentry, connective tissues, smooth muscle, blood vessels.		* '''{{mesoderm}}''' (splanchnic) - mesentry, connective tissues, smooth muscle, blood vessels.

	* '''~~Ectoderm~~''' (neural crest) - enteric nervous system.		* '''{{ectoderm}}''' (neural crest) - enteric nervous system.

	Both endoderm and mesoderm will ~~contribute~~ to associated organs.		Both endoderm and mesoderm will also have major contributions to associated organs.

Z8600021 at 05:43, 2 August 2018

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	{\| class="wikitable mw-collapsible mw-collapsed"		{\| class="wikitable mw-collapsible mw-collapsed"
	! ~~Midgut Rotation -~~ Recent ~~Article~~		! Some Recent Articles
	\|-		\|-
	\| [[File:Human embryo midgut loop 01.jpg\|600px]]		\| '''Tongue'''

			{{#pmid:29945863}}
			:"Adult tongue epithelium is continuously renewed from epithelial progenitor cells, a process that requires hedgehog (HH) signaling. In summary, we show that SOX2 functions downstream of HH signaling to regulate lingual epithelium homeostasis." {{SOX}}

			{{#pmid:29784581}}
			:"Although the gross embryological contributions to tongue formation have been known for many years, it is only relatively recently that the molecular pathways regulating these processes have begun to be discovered. In particular, there is now evidence that the Hedgehog, {{TGF-beta}}, {{WNT}} and {{Notch}} signaling pathways all play an important role in mediating appropriate signaling interactions between the epithelial, cranial neural crest and mesodermal cell populations that are required to form the tongue."
			\|-
			\| '''Midgut Rotation'''

			[[File:Human embryo midgut loop 01.jpg\|600px]]

	[[Carnegie stage 14]] (CS14) orientation of the midgut loop and its mesentery during the 5th week follows the helical body axis.		[[Carnegie stage 14]] (CS14) orientation of the midgut loop and its mesentery during the 5th week follows the helical body axis.

Z8600021 at 00:46, 2 August 2018

2018-08-02T00:46:47Z

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	Note that we will be returning in the laboratory and later (head, endocrine, neural crest) to discuss the gastrointestinal tract, associated organs and physical growth changes.		Note that we will be returning in the laboratory and later (head, endocrine, neural crest) to discuss the gastrointestinal tract, associated organs and physical growth changes.



	~~{\| class="wikitable mw-collapsible mw-collapsed"~~
	~~! colspan=2\|2015 Lecture - Video and Audio  ~~
	\|-
	~~\| '''Lecture Video'''~~

	~~<html5media>File:ANAT2341-2015Lecture-GIT.mp4‎</html5media>~~

	~~[[Media:ANAT2341-2015Lecture-GIT.mp4‎\|Video (in new window)]]~~

	~~'''Lecture Audio'''~~

	~~<html5media>File:ANAT2341-2015Lecture-GIT.mp3</html5media>~~

	~~[[Media:ANAT2341-2015Lecture-GIT.mp3\|Audio (in new window)]]~~
	~~\| See also~~
	~~<br>~~
	~~{{OneMinuteClock}}<br>~~
	~~<br>~~
	~~[[One_Minute_Embryology#Endoderm_Development\|'''1 Minute Embryology''']]~~

	~~[https://thebox.unsw.edu.au/video/1-minute-embryology-endoderm-development UNSW theBox]~~
	\|}

	{\| class="wikitable mw-collapsible mw-collapsed"		{\| class="wikitable mw-collapsible mw-collapsed"
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	==Lecture Resources==		==Lecture Resources==
	{\| class="wikitable mw-collapsible mw-collapsed"		{\| class="wikitable mw-collapsible mw-collapsed"
	! Movies		! Movies
	\|-		\|-
	\| colspan=2 valign="bottom"\|{{GIT_cartoons}}		\| colspan=2 valign="bottom"\|{{GIT_cartoons}}
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	\|		\|
	{{Gastrointestinal Tract Links}}		{{Gastrointestinal Tract Links}}
	* Lecture Archive: [[Media:2015ANAT2341_Lecture_9_-_Gastrointestinal Development.pdf\|2015 PDF]]		* Lecture Archive: [https://embryology.med.unsw.edu.au/embryology/index.php?title=Lecture_-_Gastrointestinal_Development&oldid=301545 2017] \| [[Media:2015ANAT2341_Lecture_9_-_Gastrointestinal Development.pdf\|2015 PDF]]
	[https://embryology.med.unsw.edu.au/embryology/index.php?title=Lecture_-_Gastrointestinal_Development&oldid=195582 2014] \| [[Media:ANAT2341_Lecture_9_-_2014_Gastrointestinal_Development.pdf\|2014 PDF]]		[https://embryology.med.unsw.edu.au/embryology/index.php?title=Lecture_-_Gastrointestinal_Development&oldid=195582 2014] \| [[Media:ANAT2341_Lecture_9_-_2014_Gastrointestinal_Development.pdf\|2014 PDF]]
	\|-		\|-
	\| {{MPT2011cover_citation}}		\| {{MPT2011cover_citation}}
	\| The following chapter links only work with a UNSW connection.		\| The following chapter links only work with a UNSW connection.
	* [~~http~~://~~www.unsw.eblib.~~com.~~wwwproxy0~~.library.unsw.edu.au/~~patron~~/~~Read~~.~~aspx~~?p=~~1430154~~&pg=~~235~~ Alimentary System]		* Chapter 11 [https://ebookcentral-proquest-com.wwwproxy1.library.unsw.edu.au/lib/unsw/reader.action?docID=2074364&ppg=286 Alimentary System]
	\|-		\|-
	\| {{SBBF2009cover_citation}}		\| {{SBBF2009cover_citation}}
	\| The following chapter links only work with a UNSW connection.		\| The following chapter links only work with a UNSW connection.
	* Chapter 14 - Development of the Gastrointestinal Tract		Chapter 14 [https://ebookcentral-proquest-com.wwwproxy1.library.unsw.edu.au/lib/unsw/reader.action?docID=2074524&ppg=359 Development of the Gastrointestinal Tract]
	\|}		\|}
			{\| class="wikitable mw-collapsible mw-collapsed"
			! colspan=2\|2015 Lecture - Video and Audio
			\|-
			\| '''Lecture Video'''

			<html5media>File:ANAT2341-2015Lecture-GIT.mp4‎</html5media>

			[[Media:ANAT2341-2015Lecture-GIT.mp4‎\|Video (in new window)]]

			'''Lecture Audio'''

			<html5media>File:ANAT2341-2015Lecture-GIT.mp3</html5media>

			[[Media:ANAT2341-2015Lecture-GIT.mp3\|Audio (in new window)]]
			\| See also
			<br>
			{{OneMinuteClock}}<br>
			<br>
			[[One_Minute_Embryology#Endoderm_Development\|'''1 Minute Embryology''']]

			[https://thebox.unsw.edu.au/video/1-minute-embryology-endoderm-development UNSW theBox]
			\|}
	== Germ Layer Contributions ==		== Germ Layer Contributions ==

Z8600021 at 01:49, 8 Haziran 2018

2018-06-08T01:49:52Z

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	{\| class="wikitable mw-collapsible mw-collapsed"		{\| class="wikitable mw-collapsible mw-collapsed"
	! colspan=2\|Lecture - Video and Audio ~~(to be watched on or before Monday)~~		! colspan=2\|2015 Lecture - Video and Audio
	\|-		\|-
	\| '''Lecture Video'''		\| '''Lecture Video'''
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	{\| class="wikitable mw-collapsible mw-collapsed"		{\| class="wikitable mw-collapsible mw-collapsed"
	! Midgut Rotation - Recent Article		! Midgut Rotation - Recent Article
	\|-		\|-
	\| [[File:Human embryo midgut loop 01.jpg\|600px]]		\| [[File:Human embryo midgut loop 01.jpg\|600px]]

Z8600021 at 01:43, 8 Haziran 2018

2018-06-08T01:43:54Z

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	{{Glossary}}		{{Glossary}}

	{{~~2017ANAT2341 footer~~}}		{{2018ANAT2341}}

	{{Footer}}		{{Footer}}
	[[Category:Gastrointestinal Tract]]		[[Category:Gastrointestinal Tract]]