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	<id>https://embryology.med.unsw.edu.au/embryology/index.php?action=history&amp;feed=atom&amp;title=Gastrointestinal_Tract_-_Gallbladder_Histology</id>
	<title>Gastrointestinal Tract - Gallbladder Histology - Revision history</title>
	<link rel="self" type="application/atom+xml" href="https://embryology.med.unsw.edu.au/embryology/index.php?action=history&amp;feed=atom&amp;title=Gastrointestinal_Tract_-_Gallbladder_Histology"/>
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	<updated>2026-11-02T13:58:25Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://embryology.med.unsw.edu.au/embryology/index.php?title=Gastrointestinal_Tract_-_Gallbladder_Histology&amp;diff=377470&amp;oldid=prev</id>
		<title>Z8600021 at 04:56, 20 April 2019</title>
		<link rel="alternate" type="text/html" href="https://embryology.med.unsw.edu.au/embryology/index.php?title=Gastrointestinal_Tract_-_Gallbladder_Histology&amp;diff=377470&amp;oldid=prev"/>
		<updated>2019-04-20T04:56:01Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 15:56, 20 April 2019&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l53&quot;&gt;Line 53:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 53:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br/&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br/&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;* random orientation of smooth muscle cells (fibers)&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;* random orientation of smooth muscle cells (fibers)&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;* '''muscularis propria''' (or fibromuscular coat)&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;ref&amp;gt;&amp;lt;pubmed&amp;gt;&lt;/del&gt;21074688&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;/pubmed&amp;gt;&amp;lt;/ref&amp;gt;&lt;/del&gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;* '''muscularis propria''' (or fibromuscular coat)&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;{{#pmid:&lt;/ins&gt;21074688&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;|PMID21074688}}&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;** not like the rest of GIT smooth muscle organisation, which is divided into muscularis mucosa (inside submucosa), muscularis externa (circular and longitudinal)&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;** not like the rest of GIT smooth muscle organisation, which is divided into muscularis mucosa (inside submucosa), muscularis externa (circular and longitudinal)&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;** various terminology used for this layer in different sources&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;** various terminology used for this layer in different sources&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;

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		<author><name>Z8600021</name></author>
	</entry>
	<entry>
		<id>https://embryology.med.unsw.edu.au/embryology/index.php?title=Gastrointestinal_Tract_-_Gallbladder_Histology&amp;diff=368932&amp;oldid=prev</id>
		<title>Z8600021: Created page with &quot;{{Header}} ==Introduction== Gallbladder transverse section historic drawing. This section of notes gives an overview mainly of adult {{gallbl...&quot;</title>
		<link rel="alternate" type="text/html" href="https://embryology.med.unsw.edu.au/embryology/index.php?title=Gastrointestinal_Tract_-_Gallbladder_Histology&amp;diff=368932&amp;oldid=prev"/>
		<updated>2019-01-23T03:39:04Z</updated>

		<summary type="html">&lt;p&gt;Created page with &amp;quot;{{Header}} ==Introduction== &lt;a href=&quot;/embryology/index.php?title=File:Gray1096.jpg&quot; title=&quot;File:Gray1096.jpg&quot;&gt;thumb|300px|Gallbladder transverse section historic drawing.&lt;/a&gt; This section of notes gives an overview mainly of adult {{gallbl...&amp;quot;&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;{{Header}}&lt;br /&gt;
==Introduction==&lt;br /&gt;
[[File:Gray1096.jpg|thumb|300px|Gallbladder transverse section historic drawing.]]&lt;br /&gt;
This section of notes gives an overview mainly of adult {{gallbladder}} histology. Note that the term &amp;quot;gall bladder&amp;quot; can also be used for this organ.&lt;br /&gt;
&lt;br /&gt;
[[File:HMsmall.jpg|left]] Page also provides further background information for Medicine phase 1 Health Maintenance B Hepatobiliary System 2 Practical [http://vslides.unsw.edu.au/VirtualSlideV2.nsf/id/9F207C Virtual Slides]. '''This page content is not part of the HMB practical class.'''&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
::'''HMB:''' [[Gastrointestinal Tract - Pancreas Histology|Pancreas Histology]] | [[Gastrointestinal_Tract_-_Liver_Histology|Liver Histology]] | [[Gastrointestinal_Tract_-_Gall_Bladder_Histology|Gallbladder Histology]] | [[Renal System Histology]] &lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
{{Template:Gastrointestinal Tract Links}}&lt;br /&gt;
&lt;br /&gt;
===Lab Audio===&lt;br /&gt;
&lt;br /&gt;
[[File:Podcast_icon.jpg]] Wednesday 24 August 2011 3-3:30 pm G2G4.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
{{AudioHMBGallBladder2011}}&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
==Gallbladder Structure==&lt;br /&gt;
===Anatomy===&lt;br /&gt;
* Pear-shaped&lt;br /&gt;
* distensible sac (about 50ml volume)&lt;br /&gt;
* Attached to posterioinferior surface of liver&lt;br /&gt;
* Embryonic - foregut, forms from primitive bile duct&lt;br /&gt;
* leads to cystic duct  &lt;br /&gt;
** Liver -&amp;gt; hepatic duct&lt;br /&gt;
** Gallbladder -&amp;gt; cystic duct&lt;br /&gt;
** Common Bile duct&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
Macroscopic Mucosal features:&lt;br /&gt;
* Mucosa (epithelium + lamina propria)&lt;br /&gt;
** Mucosal folds&lt;br /&gt;
** Rokitansky-Aschoff sinuses&lt;br /&gt;
* Serosa/Adventitia (dense CT + visceral mesothelium)&lt;br /&gt;
&lt;br /&gt;
===Epithelium===&lt;br /&gt;
* Columnar epithelium with microvilli (absorptive epithelium)&lt;br /&gt;
** Epithelium lining the biliary system does not contain mucus-producing cells (few located in neck of gall bladder)&lt;br /&gt;
* Basement membrane (not basal lamina which forms part of basement membrane and only visible by EM)&lt;br /&gt;
&lt;br /&gt;
===Lamina Propria===&lt;br /&gt;
* connective tissue&lt;br /&gt;
* collagen fibers and fibroblasts&lt;br /&gt;
* fenestrated capillaries and venules&lt;br /&gt;
* lymphocytes and plasma cells&lt;br /&gt;
&lt;br /&gt;
===Smooth Muscle Layer===&lt;br /&gt;
&lt;br /&gt;
* random orientation of smooth muscle cells (fibers)&lt;br /&gt;
* '''muscularis propria''' (or fibromuscular coat)&amp;lt;ref&amp;gt;&amp;lt;pubmed&amp;gt;21074688&amp;lt;/pubmed&amp;gt;&amp;lt;/ref&amp;gt;&lt;br /&gt;
** not like the rest of GIT smooth muscle organisation, which is divided into muscularis mucosa (inside submucosa), muscularis externa (circular and longitudinal)&lt;br /&gt;
** various terminology used for this layer in different sources&lt;br /&gt;
&lt;br /&gt;
===Serosa/Adventitia===&lt;br /&gt;
* Dense connective tissue layer covered with visceral mesothelium epithelial layer&lt;br /&gt;
** Adventitia - where it is attached to the liver&lt;br /&gt;
** Serosa - where it is free in the peritoneum&lt;br /&gt;
* Large blood vessels (arteries, veins)&lt;br /&gt;
* Obvious lymphatic vessels&lt;br /&gt;
* Autonomic nerve bundles&lt;br /&gt;
* Adipose tissue&lt;br /&gt;
&lt;br /&gt;
==Gall Bladder Function==&lt;br /&gt;
* bile storage&lt;br /&gt;
* bile concentration&lt;br /&gt;
* bile release&lt;br /&gt;
&lt;br /&gt;
==Histology Images==&lt;br /&gt;
&lt;br /&gt;
===Development Histology===&lt;br /&gt;
&lt;br /&gt;
===Adult Histology===&lt;br /&gt;
&lt;br /&gt;
[[File:Gall bladder histology 001.jpg|400px]] [[File:Gall bladder histology 002.jpg|400px]]&lt;br /&gt;
&lt;br /&gt;
[[File:Gall_bladder_histology_003.jpg|400px]] [[File:Gall_bladder_histology_004.jpg|400px]]&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
See also [[:File:Gall bladder histology 005.gif|Animated labeled image]]&lt;br /&gt;
&lt;br /&gt;
==References==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references/&amp;gt;&lt;br /&gt;
&lt;br /&gt;
==Historic==&lt;br /&gt;
[[Embryology Historic Terminology]]&lt;br /&gt;
* '''Luschka ducts'''  (duct of Luschka) is historic term referring to an accessory bile duct.&lt;br /&gt;
&lt;br /&gt;
* '''folds of Heister''' (spiral valves of Heister) are undulating folds containing muscle fibers in the proximal mucosa of the cystic duct. First described by Heister in 1732. [https://www.ncbi.nlm.nih.gov/pubmed/15696536 PMID: 15696536]&lt;br /&gt;
&lt;br /&gt;
==External Links==&lt;br /&gt;
{{External Links}}&lt;br /&gt;
&lt;br /&gt;
* '''Blue Histology''' [http://www.lab.anhb.uwa.edu.au/mb140/CorePages/Liver/liver.htm#LabGall Gallbladder]&lt;br /&gt;
* '''UNSW Virtual Slides''' Medicine phase 1 [http://vslides.unsw.edu.au/VirtualSlideV2.nsf/id/9F207C Health Maintenance B Hepatobiliary System 2 Practical] (requires login for access).&lt;br /&gt;
* '''UIOWA Virtual Slidebox of Histology''' [http://www.path.uiowa.edu/cgi-bin-pub/vs/fpx_browse.cgi?cat=o_liver&amp;amp;div=nlm Liver and biliary system]&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
{{Glossary}}&lt;br /&gt;
{{Footer}}&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
[[Category:Liver]] [[Category:Histology]] [[Category:Gallbladder]]&lt;/div&gt;</summary>
		<author><name>Z8600021</name></author>
	</entry>
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