File talk:Fetal small Intestine length growth graph.jpg - Revision history

S8600021 at 23:59, 16 October 2011

2011-10-16T23:59:22Z

← Older revision		Revision as of 10:59, 17 October 2011
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			Data http://autopsy.jarchie.com

	===Normal length of the human fetal gastrointestinal tract===		===Normal length of the human fetal gastrointestinal tract===

S8600021 at 23:56, 16 October 2011

2011-10-16T23:56:19Z

← Older revision		Revision as of 10:56, 17 October 2011
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	Little information is available on the normal length of the gastrointestinal tract in fetuses or on factors that may affect its growth. To determine normal growth patterns of the fetal intestine, 58 fetuses received in the Central Laboratory for Human Embryology between January 1, 1987, and July 1, 1988, in which no abnormalities were noted on autopsy, were studied. The gastrointestinal tract was removed from the fetus en bloc from the esophagogastric junction to the pelvic floor and dissected. Measurements of stomach, small and large intestines, and appendix length were made and correlated with gestational age as determined by footlength. Overall growth of the gastrointestinal tract as well as that of each component was linear with respect to gestational age. In addition, five fetuses with omphalocele, 16 with cardiac malformations, and 20 with chromosomal abnormalities were studied. The total lengths of the gastrointestinal tracts in the first group were below the normal range in four of five fetuses. Those with cardiac defects had intestinal lengths below the mean, but the measurements were abnormal in only three. In both groups those fetuses with chromosomal abnormalities appeared to have shorter intestinal tracts than those with normal or unknown karyotypes. The gastrointestinal tracts of aneuploid fetuses fell within the normal range until approximately 20 weeks gestation, after which growth decreased. This growth failure may reflect the growth retardation seen in fetuses with chromosomal abnormalities.		Little information is available on the normal length of the gastrointestinal tract in fetuses or on factors that may affect its growth. To determine normal growth patterns of the fetal intestine, 58 fetuses received in the Central Laboratory for Human Embryology between January 1, 1987, and July 1, 1988, in which no abnormalities were noted on autopsy, were studied. The gastrointestinal tract was removed from the fetus en bloc from the esophagogastric junction to the pelvic floor and dissected. Measurements of stomach, small and large intestines, and appendix length were made and correlated with gestational age as determined by footlength. Overall growth of the gastrointestinal tract as well as that of each component was linear with respect to gestational age. In addition, five fetuses with omphalocele, 16 with cardiac malformations, and 20 with chromosomal abnormalities were studied. The total lengths of the gastrointestinal tracts in the first group were below the normal range in four of five fetuses. Those with cardiac defects had intestinal lengths below the mean, but the measurements were abnormal in only three. In both groups those fetuses with chromosomal abnormalities appeared to have shorter intestinal tracts than those with normal or unknown karyotypes. The gastrointestinal tracts of aneuploid fetuses fell within the normal range until approximately 20 weeks gestation, after which growth decreased. This growth failure may reflect the growth retardation seen in fetuses with chromosomal abnormalities.

	PMID: 3244599		PMID 3244599


			===Quantitative standards for fetal and neonatal autopsy===
	Am J Clin Pathol. 2006 Aug;126(2):256-65.		Am J Clin Pathol. 2006 Aug;126(2):256-65.
	~~Quantitative standards for fetal and neonatal autopsy.~~
	Archie JG, Collins JS, Lebel RR.		Archie JG, Collins JS, Lebel RR.
	Source		Source
	Office of Epidemiology, Greenwood Genetic Center, Greenwood, SC, USA.		Office of Epidemiology, Greenwood Genetic Center, Greenwood, SC, USA.

	Abstract		Abstract

	Growth curves are essential for determining whether growth parameters lie within normal ranges. In the case of fetal and neonatal autopsy, relevant data are scattered across many publications, and few sources examine a large enough sample to be considered definitive. To ameliorate these inadequacies, regressions were created incorporating data from multiple sources both to increase accuracy and to condense available data into a single standard. When measurements were not well studied, the best available published standards are given. These regressions provide a valuable tool for clinicians who need to understand the significance of measurements obtained during autopsy.		Growth curves are essential for determining whether growth parameters lie within normal ranges. In the case of fetal and neonatal autopsy, relevant data are scattered across many publications, and few sources examine a large enough sample to be considered definitive. To ameliorate these inadequacies, regressions were created incorporating data from multiple sources both to increase accuracy and to condense available data into a single standard. When measurements were not well studied, the best available published standards are given. These regressions provide a valuable tool for clinicians who need to understand the significance of measurements obtained during autopsy.

	PMID: 16891202		PMID 16891202

S8600021 at 14:23, 31 Mayıs 2011

2011-05-31T14:23:26Z

← Older revision		Revision as of 01:23, 1 Haziran 2011
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	===Normal length of the human fetal gastrointestinal tract===		===Normal length of the human fetal gastrointestinal tract===

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	PMID: 3244599		PMID: 3244599

			Am J Clin Pathol. 2006 Aug;126(2):256-65.
			Quantitative standards for fetal and neonatal autopsy.
			Archie JG, Collins JS, Lebel RR.
			Source
			Office of Epidemiology, Greenwood Genetic Center, Greenwood, SC, USA.
			Abstract
			Growth curves are essential for determining whether growth parameters lie within normal ranges. In the case of fetal and neonatal autopsy, relevant data are scattered across many publications, and few sources examine a large enough sample to be considered definitive. To ameliorate these inadequacies, regressions were created incorporating data from multiple sources both to increase accuracy and to condense available data into a single standard. When measurements were not well studied, the best available published standards are given. These regressions provide a valuable tool for clinicians who need to understand the significance of measurements obtained during autopsy.

			PMID: 16891202

S8600021: Created page with " ===Normal length of the human fetal gastrointestinal tract=== Pediatr Pathol. 1988;8(6):633-41. FitzSimmons J, Chinn A, Shepard TH. Source Department of Obstetrics and Gynecol..."

2011-05-31T14:15:44Z

Created page with " ===Normal length of the human fetal gastrointestinal tract=== Pediatr Pathol. 1988;8(6):633-41. FitzSimmons J, Chinn A, Shepard TH. Source Department of Obstetrics and Gynecol..."

New page

===Normal length of the human fetal gastrointestinal tract===

Pediatr Pathol. 1988;8(6):633-41.

FitzSimmons J, Chinn A, Shepard TH.
Source
Department of Obstetrics and Gynecology, University of Washington, Seattle 98155.

Abstract

Little information is available on the normal length of the gastrointestinal tract in fetuses or on factors that may affect its growth. To determine normal growth patterns of the fetal intestine, 58 fetuses received in the Central Laboratory for Human Embryology between January 1, 1987, and July 1, 1988, in which no abnormalities were noted on autopsy, were studied. The gastrointestinal tract was removed from the fetus en bloc from the esophagogastric junction to the pelvic floor and dissected. Measurements of stomach, small and large intestines, and appendix length were made and correlated with gestational age as determined by footlength. Overall growth of the gastrointestinal tract as well as that of each component was linear with respect to gestational age. In addition, five fetuses with omphalocele, 16 with cardiac malformations, and 20 with chromosomal abnormalities were studied. The total lengths of the gastrointestinal tracts in the first group were below the normal range in four of five fetuses. Those with cardiac defects had intestinal lengths below the mean, but the measurements were abnormal in only three. In both groups those fetuses with chromosomal abnormalities appeared to have shorter intestinal tracts than those with normal or unknown karyotypes. The gastrointestinal tracts of aneuploid fetuses fell within the normal range until approximately 20 weeks gestation, after which growth decreased. This growth failure may reflect the growth retardation seen in fetuses with chromosomal abnormalities.

PMID: 3244599