File:Zebrafish ectodermal patterning model.jpg - Revision history

Z8600021: /* Two-step model for zebrafish ectodermal patterning */

2020-06-29T00:43:28Z

Two-step model for zebrafish ectodermal patterning

← Older revision		Revision as of 10:43, 29 Haziran 2020
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	==Two-step model for zebrafish ectodermal patterning==		==Two-step model for zebrafish ectodermal patterning==

	'''Step 1''' depicts the DV gradient present during gastrulation. High BMP activity is observed ventrally as generated by bmp2b/4/7a ligand expression and reinforced by Cvl2. BMP activity is inhibited dorsally by expression of the diffusible antagonists Chordin and Noggin. Prospective PPE and NC are formed at intermediate levels of BMP signalling.		'''Step 1''' depicts the DV gradient present during gastrulation. High {{BMP}} activity is observed ventrally as generated by bmp2b/4/7a ligand expression and reinforced by Cvl2. BMP activity is inhibited dorsally by expression of the diffusible antagonists Chordin and {{Noggin}}. Prospective PPE and NC are formed at intermediate levels of BMP signalling.

	'''Step 2''' the initial gradient has reshaped into distinct BMP activity domains during neurulation. The regulatory network is depicted. Components in black act positively, whereas those in red act negatively. NC, neural crest; PPE, preplacodal ectoderm.		'''Step 2''' the initial gradient has reshaped into distinct BMP activity domains during neurulation. The regulatory network is depicted. Components in black act positively, whereas those in red act negatively. NC, neural crest; PPE, preplacodal ectoderm.



			:'''Links:''' {{gastrulation}} \| {{BMP}} \| {{WNT}} \| {{NOGGIN}} \| {{NODAL}}

	===Reference===		===Reference===
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	© 2013. Published by The Company of Biologists Ltd This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.		© 2013. Published by The Company of Biologists Ltd This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

	[[Category:Zebrafish]][[Category:Ectoderm]][[Category:Cartoon]]		{{footer}}
			[[Category:Zebrafish]][[Category:Ectoderm]][[Category:Cartoon]][[Category:BMP]][[Category:Gastrulation]]

Z8600021: /* Reference */

2018-12-20T02:52:56Z

Reference

← Older revision		Revision as of 12:52, 20 December 2018
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	===Reference===		===Reference===
			{{#pmid:24089471}}
	~~<pubmed>~~24089471~~</pubmed>\| [http://dev.biologists.org/content/140/21/4435.full?sid=f4d5ee3c-1ddc-44e4-9174-82c75a2e9577 Development]~~

	====Copyright====		====Copyright====

Z8600021 at 12:46, 3 March 2015

2015-03-03T12:46:52Z

← Older revision		Revision as of 22:46, 3 March 2015
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	==Two-step model for zebrafish ectodermal patterning==		==Two-step model for zebrafish ectodermal patterning==

	Step 1 depicts the DV gradient present during gastrulation. High BMP activity is observed ventrally as generated by bmp2b/4/7a ligand expression and reinforced by Cvl2. BMP activity is inhibited dorsally by expression of the diffusible antagonists Chordin and Noggin. Prospective PPE and NC are formed at intermediate levels of BMP signalling.		'''Step 1''' depicts the DV gradient present during gastrulation. High BMP activity is observed ventrally as generated by bmp2b/4/7a ligand expression and reinforced by Cvl2. BMP activity is inhibited dorsally by expression of the diffusible antagonists Chordin and Noggin. Prospective PPE and NC are formed at intermediate levels of BMP signalling.

	Step 2 the initial gradient has reshaped into distinct BMP activity domains during neurulation. The regulatory network is depicted. Components in black act positively, whereas those in red act negatively. NC, neural crest; PPE, preplacodal ectoderm.		'''Step 2''' the initial gradient has reshaped into distinct BMP activity domains during neurulation. The regulatory network is depicted. Components in black act positively, whereas those in red act negatively. NC, neural crest; PPE, preplacodal ectoderm.


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	© 2013. Published by The Company of Biologists Ltd This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.		© 2013. Published by The Company of Biologists Ltd This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

			[[Category:Zebrafish]][[Category:Ectoderm]][[Category:Cartoon]]

Z8600021 at 12:46, 3 March 2015

2015-03-03T12:46:01Z

← Older revision		Revision as of 22:46, 3 March 2015
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	~~A two~~-step model for zebrafish ectodermal patterning. Step 1 depicts the DV gradient present during gastrulation. High BMP activity is observed ventrally as generated by bmp2b/4/7a ligand expression and reinforced by Cvl2. BMP activity is inhibited dorsally by expression of the diffusible antagonists Chordin and Noggin. Prospective PPE and NC are formed at intermediate levels of BMP signalling. ~~In step~~ 2 the initial gradient has reshaped into distinct BMP activity domains during neurulation. The regulatory network is depicted. Components in black act positively, whereas those in red act negatively. NC, neural crest; PPE, preplacodal ectoderm.		==Two-step model for zebrafish ectodermal patterning==

			Step 1 depicts the DV gradient present during gastrulation. High BMP activity is observed ventrally as generated by bmp2b/4/7a ligand expression and reinforced by Cvl2. BMP activity is inhibited dorsally by expression of the diffusible antagonists Chordin and Noggin. Prospective PPE and NC are formed at intermediate levels of BMP signalling.

			Step 2 the initial gradient has reshaped into distinct BMP activity domains during neurulation. The regulatory network is depicted. Components in black act positively, whereas those in red act negatively. NC, neural crest; PPE, preplacodal ectoderm.


	===Reference===		===Reference===

	~~PMID~~ 24089471		<pubmed>24089471</pubmed>\| [http://dev.biologists.org/content/140/21/4435.full?sid=f4d5ee3c-1ddc-44e4-9174-82c75a2e9577 Development]

	http://dev.biologists.org/content/140/21/4435.full?sid=f4d5ee3c-1ddc-44e4-9174-82c75a2e9577

	====Copyright====		====Copyright====

	© 2013. Published by The Company of Biologists Ltd This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.		© 2013. Published by The Company of Biologists Ltd This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Z8600021: A two-step model for zebrafish ectodermal patterning. Step 1 depicts the DV gradient present during gastrulation. High BMP activity is observed ventrally as generated by bmp2b/4/7a ligand expression and reinforced by Cvl2. BMP activity is inhibited dor...

2015-03-03T12:44:54Z

New page

A two-step model for zebrafish ectodermal patterning. Step 1 depicts the DV gradient present during gastrulation. High BMP activity is observed ventrally as generated by bmp2b/4/7a ligand expression and reinforced by Cvl2. BMP activity is inhibited dorsally by expression of the diffusible antagonists Chordin and Noggin. Prospective PPE and NC are formed at intermediate levels of BMP signalling. In step 2 the initial gradient has reshaped into distinct BMP activity domains during neurulation. The regulatory network is depicted. Components in black act positively, whereas those in red act negatively. NC, neural crest; PPE, preplacodal ectoderm.

===Reference===

PMID 24089471

http://dev.biologists.org/content/140/21/4435.full?sid=f4d5ee3c-1ddc-44e4-9174-82c75a2e9577

====Copyright====

© 2013. Published by The Company of Biologists Ltd This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.