File:TGF-beta signaling pathway.jpg - Revision history

S8600021: /* Basic overview of TGF-β signalling pathway */

2011-09-10T06:59:54Z

Basic overview of TGF-β signalling pathway

← Older revision		Revision as of 17:59, 10 September 2011
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	The pathway can be inhibited by extracelluar antagonists, or intracellularly via Inhibitor-Smad (Smad6/7) or the ubiquitin ligase SMURF.		The pathway can be inhibited by extracelluar antagonists, or intracellularly via Inhibitor-Smad (Smad6/7) or the ubiquitin ligase SMURF.

	{{Template:Factor Links}}
			:{{Template:Factor Links}}

S8600021: /* Basic overview of TGF-β signalling pathway */

2011-09-10T06:59:40Z

Basic overview of TGF-β signalling pathway

← Older revision		Revision as of 17:59, 10 September 2011
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	==Basic overview of TGF-β signalling pathway==		==Basic overview of TGF-β signalling pathway==

	Binding of a ligand to a Type II receptor initiates signaling. The sequestering of a Type I receptor results in the activation of a Receptor-Smad (Smad1/5, Smad2/3). Together with the Co-Smad (Smad4), this complex enters the nucleus and activates the transcription of target genes. The pathway can be inhibited by extracelluar antagonists, or intracellularly via Inhibitor-Smad (Smad6/7) or the ubiquitin ligase SMURF.		# Binding of a ligand to a Type II receptor initiates signaling.
			# The sequestering of a Type I receptor results in the activation of a Receptor-Smad (Smad1/5, Smad2/3).
			# Together with the Co-Smad (Smad4), this complex enters the nucleus and activates the transcription of target genes.

			The pathway can be inhibited by extracelluar antagonists, or intracellularly via Inhibitor-Smad (Smad6/7) or the ubiquitin ligase SMURF.

	{{Template:Factor Links}}		{{Template:Factor Links}}

S8600021 at 04:59, 10 September 2011

2011-09-10T04:59:46Z

← Older revision		Revision as of 15:59, 10 September 2011
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	© 2011 Pang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.		© 2011 Pang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

			[[Category:TGF-beta]]
	[[Category:Molecular]] [[Category:Cartoon]]		[[Category:Molecular]] [[Category:Cartoon]]

S8600021 at 04:34, 10 September 2011

2011-09-10T04:34:10Z

← Older revision		Revision as of 15:34, 10 September 2011
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	Binding of a ligand to a Type II receptor initiates signaling. The sequestering of a Type I receptor results in the activation of a Receptor-Smad (Smad1/5, Smad2/3). Together with the Co-Smad (Smad4), this complex enters the nucleus and activates the transcription of target genes. The pathway can be inhibited by extracelluar antagonists, or intracellularly via Inhibitor-Smad (Smad6/7) or the ubiquitin ligase SMURF.		Binding of a ligand to a Type II receptor initiates signaling. The sequestering of a Type I receptor results in the activation of a Receptor-Smad (Smad1/5, Smad2/3). Together with the Co-Smad (Smad4), this complex enters the nucleus and activates the transcription of target genes. The pathway can be inhibited by extracelluar antagonists, or intracellularly via Inhibitor-Smad (Smad6/7) or the ubiquitin ligase SMURF.

			{{Template:Factor Links}}

S8600021 at 04:13, 10 September 2011

2011-09-10T04:13:55Z

← Older revision		Revision as of 15:13, 10 September 2011
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	Binding of a ligand to a Type II receptor initiates signaling. The sequestering of a Type I receptor results in the activation of a Receptor-Smad (Smad1/5, Smad2/3). Together with the Co-Smad (Smad4), this complex enters the nucleus and activates the transcription of target genes. The pathway can be inhibited by extracelluar antagonists, or intracellularly via Inhibitor-Smad (Smad6/7) or the ubiquitin ligase SMURF.		Binding of a ligand to a Type II receptor initiates signaling. The sequestering of a Type I receptor results in the activation of a Receptor-Smad (Smad1/5, Smad2/3). Together with the Co-Smad (Smad4), this complex enters the nucleus and activates the transcription of target genes. The pathway can be inhibited by extracelluar antagonists, or intracellularly via Inhibitor-Smad (Smad6/7) or the ubiquitin ligase SMURF.


	Original file name: Figure 1. Journal.pone.0024152.g001.jpg dpi:10.1371/journal.pone.0024152.g001		Original file name: Figure 1. Journal.pone.0024152.g001.jpg dpi:10.1371/journal.pone.0024152.g001
			===Reference===
			Pang K, Ryan JF, Baxevanis AD, Martindale MQ (2011) Evolution of the TGF-β Signaling Pathway and Its Potential Role in the Ctenophore,
			Mnemiopsis leidyi. PLoS ONE 6(9): e24152. [http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0024152 PLoS ONE]




			© 2011 Pang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

			[[Category:Molecular]] [[Category:Cartoon]]

S8600021: ==Basic overview of TGF-β signalling pathway== Binding of a ligand to a Type II receptor initiates signaling. The sequestering of a Type I receptor results in the activation of a Receptor-Smad (Smad1/5, Smad2/3). Together with the Co-Smad (Smad4), this

2011-09-10T04:11:26Z

New page

==Basic overview of TGF-β signalling pathway==

Binding of a ligand to a Type II receptor initiates signaling. The sequestering of a Type I receptor results in the activation of a Receptor-Smad (Smad1/5, Smad2/3). Together with the Co-Smad (Smad4), this complex enters the nucleus and activates the transcription of target genes. The pathway can be inhibited by extracelluar antagonists, or intracellularly via Inhibitor-Smad (Smad6/7) or the ubiquitin ligase SMURF.

Original file name: Figure 1. Journal.pone.0024152.g001.jpg dpi:10.1371/journal.pone.0024152.g001