File:Schwann and axon interactions.jpg - Revision history

Z8600021 at 13:55, 9 Haziran 2016

2016-06-09T13:55:08Z

← Older revision		Revision as of 00:55, 10 Haziran 2016
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	The polarity protein Par-3 colocalizes with Necl-4 in the adaxonal region of the Schwann cell (Chan et al., 2006), and it is possible that these proteins interact via PDZ and PDZ-binding motifs (red). The Necl proteins can also interact with FERM domain proteins via the FERM-binding domain (blue). Necls are also present at the Schmidt-Lanterman incisures (inset). Necl-2 is not depicted but localizes to the axon–Schwann cell interface and to the incisures.		The polarity protein Par-3 colocalizes with Necl-4 in the adaxonal region of the Schwann cell (Chan et al., 2006), and it is possible that these proteins interact via PDZ and PDZ-binding motifs (red). The Necl proteins can also interact with FERM domain proteins via the FERM-binding domain (blue). Necls are also present at the Schmidt-Lanterman incisures (inset). Necl-2 is not depicted but localizes to the axon–Schwann cell interface and to the incisures.

	~~The figure was adapted from Voas et al. (2007).~~		===Reference===

	~~http://jcb.rupress.org/content/178/5/721/F1.large.jpg~~

	==Reference==
	<pubmed>17724116</pubmed>\| [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064536 PMC2064536] \| [http://jcb.rupress.org/content/178/5/721.full?sid=c88c798d-80b9-4eed-916b-4907068a99d5 JCB]		<pubmed>17724116</pubmed>\| [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064536 PMC2064536] \| [http://jcb.rupress.org/content/178/5/721.full?sid=c88c798d-80b9-4eed-916b-4907068a99d5 JCB]

			====Copyright====
	This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jcb.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).		This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jcb.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

			The figure was adapted from Voas et al. (2007). http://jcb.rupress.org/content/178/5/721/F1.large.jpg

			{{Footer}}
	[[Category:Glia]] [[Category:Cartoon]] [[Category:Neural]]		[[Category:Glia]] [[Category:Cartoon]] [[Category:Neural]]
			[[Category:Schwann cell]]

S8600021 at 02:52, 24 September 2010

2010-09-24T02:52:15Z

← Older revision		Revision as of 13:52, 24 September 2010
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	==Reference==		==Reference==
	<pubmed>17724116</pubmed>\| [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064536 PMC2064536] \| [http://jcb.rupress.org/content/178/5/721.full?sid=c88c798d-80b9-4eed-916b-4907068a99d5 JCB]		<pubmed>17724116</pubmed>\| [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064536 PMC2064536] \| [http://jcb.rupress.org/content/178/5/721.full?sid=c88c798d-80b9-4eed-916b-4907068a99d5 JCB]

			This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jcb.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).


	[[Category:Glia]] [[Category:Cartoon]] [[Category:Neural]]		[[Category:Glia]] [[Category:Cartoon]] [[Category:Neural]]

S8600021: /* Model of interactions between myelinating Schwann cells and axons */

2010-09-24T02:42:33Z

Model of interactions between myelinating Schwann cells and axons

← Older revision		Revision as of 13:42, 24 September 2010
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	==Model of interactions between myelinating Schwann cells and axons==		==Model of interactions between myelinating Schwann cells and axons==
			* Showing proteins that localize to the node, paranode, juxtaparanode, and internode.
			* Schwann cell, blue; axon, yellow. PN, paranode; JPN, juxtaparanode.

	~~Showing proteins that localize to the node, paranode, juxtaparanode, and internode. Schwann cell, blue; axon, yellow. PN, paranode; JPN, juxtaparanode.~~ Analysis of the Necl proteins provides important new insight into molecular complexes along the internode (Maurel et al., 2007; Spiegel et al., 2007), which had not been as well defined as for the other domains. The polarity protein Par-3 colocalizes with Necl-4 in the adaxonal region of the Schwann cell (Chan et al., 2006), and it is possible that these proteins interact via PDZ and PDZ-binding motifs (red). The Necl proteins can also interact with FERM domain proteins via the FERM-binding domain (blue). Necls are also present at the Schmidt-Lanterman incisures (inset). Necl-2 is not depicted but localizes to the axon–Schwann cell interface and to the incisures. The figure was adapted from Voas et al. (2007).		Analysis of the Necl proteins provides important new insight into molecular complexes along the internode (Maurel et al., 2007; Spiegel et al., 2007), which had not been as well defined as for the other domains.

			The polarity protein Par-3 colocalizes with Necl-4 in the adaxonal region of the Schwann cell (Chan et al., 2006), and it is possible that these proteins interact via PDZ and PDZ-binding motifs (red). The Necl proteins can also interact with FERM domain proteins via the FERM-binding domain (blue). Necls are also present at the Schmidt-Lanterman incisures (inset). Necl-2 is not depicted but localizes to the axon–Schwann cell interface and to the incisures.

			The figure was adapted from Voas et al. (2007).

	http://jcb.rupress.org/content/178/5/721/F1.large.jpg		http://jcb.rupress.org/content/178/5/721/F1.large.jpg

S8600021: ==Model of interactions between myelinating Schwann cells and axons== Showing proteins that localize to the node, paranode, juxtaparanode, and internode. Schwann cell, blue; axon, yellow. PN, paranode; JPN, juxtaparanode. Analysis of the Necl proteins pr

2010-09-24T02:41:33Z

New page

==Model of interactions between myelinating Schwann cells and axons==

Showing proteins that localize to the node, paranode, juxtaparanode, and internode. Schwann cell, blue; axon, yellow. PN, paranode; JPN, juxtaparanode. Analysis of the Necl proteins provides important new insight into molecular complexes along the internode (Maurel et al., 2007; Spiegel et al., 2007), which had not been as well defined as for the other domains. The polarity protein Par-3 colocalizes with Necl-4 in the adaxonal region of the Schwann cell (Chan et al., 2006), and it is possible that these proteins interact via PDZ and PDZ-binding motifs (red). The Necl proteins can also interact with FERM domain proteins via the FERM-binding domain (blue). Necls are also present at the Schmidt-Lanterman incisures (inset). Necl-2 is not depicted but localizes to the axon–Schwann cell interface and to the incisures. The figure was adapted from Voas et al. (2007).

http://jcb.rupress.org/content/178/5/721/F1.large.jpg

==Reference==
<pubmed>17724116</pubmed>| [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064536 PMC2064536] | [http://jcb.rupress.org/content/178/5/721.full?sid=c88c798d-80b9-4eed-916b-4907068a99d5 JCB]

[[Category:Glia]] [[Category:Cartoon]] [[Category:Neural]]