File:Placenta term anatomy 01.jpg - Revision history

Z8600021 at 01:04, 8 Mayıs 2018

2018-05-08T01:04:37Z

← Older revision		Revision as of 12:04, 8 Mayıs 2018
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	:[[Placenta Development\|'''Placenta Links''']]: [[Placenta Development]] \| [[Third Trimester]] \| [[Birth]]		:[[Placenta Development\|'''Placenta Links''']]: [[Placenta Development]] \| [[Third Trimester]] \| [[Birth]]

			{{Placenta Links}}
	===Reference===		===Reference===

	~~<pubmed>~~22523561~~</pubmed>~~\| ~~[http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0034851 PLoS One.]~~		{{#pmid:22523561\|PMID22523561}}

	====Copyright====		====Copyright====

Z8600021 at 10:31, 8 Haziran 2015

2015-06-08T10:31:25Z

← Older revision		Revision as of 21:31, 8 Haziran 2015
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	Modified from Figure 1 A and B http://www.plosone.org/article/slideshow.action?uri=info:doi/10.1371/journal.pone.0034851&imageURI=info:doi/10.1371/journal.pone.0034851.g001		Modified from Figure 1 A and B http://www.plosone.org/article/slideshow.action?uri=info:doi/10.1371/journal.pone.0034851&imageURI=info:doi/10.1371/journal.pone.0034851.g001

			{{Footer}}

	[[Category:Human]] [[Category:Placenta]] [[Category:Third Trimester]]		[[Category:Human]] [[Category:Placenta]] [[Category:Third Trimester]]

Z8600021 at 04:23, 14 April 2014

2014-04-14T04:23:42Z

← Older revision		Revision as of 15:23, 14 April 2014
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	==Placenta Term Anatomy==		==Placenta Term Anatomy==

	Image showing overall placenta structure viewed from fetal and maternal sides at term.		Image showing overall placenta structure viewed from both the fetal and maternal sides at term. 5 cm scale bar.

	5 cm scale bar.


			:[[Placenta Development\|'''Placenta Links''']]: [[Placenta Development]] \| [[Third Trimester]] \| [[Birth]]

	===Reference===		===Reference===
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	<pubmed>22523561</pubmed>\| [http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0034851 PLoS One.]		<pubmed>22523561</pubmed>\| [http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0034851 PLoS One.]

			====Copyright====
			© 2012 Warrander et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
	~~Copyright:~~ © 2012 Warrander et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



	Modified from Figure 1 A and B http://www.plosone.org/article/slideshow.action?uri=info:doi/10.1371/journal.pone.0034851&imageURI=info:doi/10.1371/journal.pone.0034851.g001		Modified from Figure 1 A and B http://www.plosone.org/article/slideshow.action?uri=info:doi/10.1371/journal.pone.0034851&imageURI=info:doi/10.1371/journal.pone.0034851.g001

Z8600021: /* Placenta Term Anatomy */

2012-06-03T03:17:49Z

Placenta Term Anatomy

← Older revision		Revision as of 14:17, 3 Haziran 2012
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	==Placenta Term Anatomy==		==Placenta Term Anatomy==

	Image showing ~~fatal~~ and maternal sides ~~of the placenta~~ at term.		Image showing overall placenta structure viewed from fetal and maternal sides at term.

	5 cm scale bar.		5 cm scale bar.

	~~[[Category:Placenta]]~~


	~~PMID~~ 22523561		===Reference===

			<pubmed>22523561</pubmed>\| [http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0034851 PLoS One.]



			Copyright: © 2012 Warrander et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



			Modified from Figure 1 A and B http://www.plosone.org/article/slideshow.action?uri=info:doi/10.1371/journal.pone.0034851&imageURI=info:doi/10.1371/journal.pone.0034851.g001


			[[Category:Human]] [[Category:Placenta]] [[Category:Third Trimester]]

Z8600021: Replaced content with "==Placenta Term Anatomy== Image showing fatal and maternal sides of the placenta at term. 5 cm scale bar. Category:Placenta PMID 22523561"

2012-06-03T03:14:37Z

Replaced content with "==Placenta Term Anatomy== Image showing fatal and maternal sides of the placenta at term. 5 cm scale bar. Category:Placenta PMID 22523561"

← Older revision		Revision as of 14:14, 3 Haziran 2012
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	[[Category:Placenta]]		[[Category:Placenta]]

	~~===Maternal perception of reduced fetal movements is associated with altered placental structure and function===~~

	~~PLoS One. 2012;7(4):e34851. Epub 2012 Apr 16.~~

	~~Warrander LK, Batra G, Bernatavicius G, Greenwood SL, Dutton P, Jones RL, Sibley CP, Heazell AE.~~
	~~Source~~
	~~School of Biomedicine, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom.~~

	~~Abstract~~

	~~BACKGROUND:~~
	Maternal perception of reduced fetal movement (RFM) is associated with increased risk of stillbirth and fetal growth restriction (FGR). DFM is thought to represent fetal compensation to conserve energy due to insufficient oxygen and nutrient transfer resulting from placental insufficiency. To date there have been no studies of placental structure in cases of DFM.
	~~OBJECTIVE:~~
	~~To determine whether maternal perception of reduced fetal movements (RFM) is associated with abnormalities in placental structure and function.~~
	~~DESIGN:~~
	Placentas were collected from women with RFM after 28 weeks gestation if delivery occurred within 1 week. Women with normal movements served as a control group. Placentas were weighed and photographs taken. Microscopic structure was evaluated by immunohistochemical staining and image analysis. System A amino acid transporter activity was measured as a marker of placental function. Placentas from all pregnancies with RFM (irrespective of outcome) had greater area with signs of infarction (3.5% vs. 0.6%; p<0.01), a higher density of syncytial knots (p<0.001) and greater proliferation index (p<0.01). Villous vascularity (p<0.001), trophoblast area (p<0.01) and system A activity (p<0.01) were decreased in placentas from RFM compared to controls irrespective of outcome of pregnancy.
	~~CONCLUSIONS:~~
	This study provides evidence of abnormal placental morphology and function in women with RFM and supports the proposition of a causal association between placental insufficiency and RFM. This suggests that women presenting with RFM require further investigation to identify those with placental insufficiency.

	PMID 22523561		PMID 22523561

Z8600021: ==Placenta Term Anatomy== Image showing fatal and maternal sides of the placenta at term. 5 cm scale bar. Category:Placenta ===Maternal perception of reduced fetal movements is associated with altered placental structure and function=== PLoS One.

2012-06-03T03:14:07Z

==Placenta Term Anatomy== Image showing fatal and maternal sides of the placenta at term. 5 cm scale bar. Category:Placenta ===Maternal perception of reduced fetal movements is associated with altered placental structure and function=== PLoS One.

New page

==Placenta Term Anatomy==

Image showing fatal and maternal sides of the placenta at term.

5 cm scale bar.

[[Category:Placenta]]

===Maternal perception of reduced fetal movements is associated with altered placental structure and function===

PLoS One. 2012;7(4):e34851. Epub 2012 Apr 16.

Warrander LK, Batra G, Bernatavicius G, Greenwood SL, Dutton P, Jones RL, Sibley CP, Heazell AE.
Source
School of Biomedicine, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom.

Abstract

BACKGROUND:
Maternal perception of reduced fetal movement (RFM) is associated with increased risk of stillbirth and fetal growth restriction (FGR). DFM is thought to represent fetal compensation to conserve energy due to insufficient oxygen and nutrient transfer resulting from placental insufficiency. To date there have been no studies of placental structure in cases of DFM.
OBJECTIVE:
To determine whether maternal perception of reduced fetal movements (RFM) is associated with abnormalities in placental structure and function.
DESIGN:
Placentas were collected from women with RFM after 28 weeks gestation if delivery occurred within 1 week. Women with normal movements served as a control group. Placentas were weighed and photographs taken. Microscopic structure was evaluated by immunohistochemical staining and image analysis. System A amino acid transporter activity was measured as a marker of placental function. Placentas from all pregnancies with RFM (irrespective of outcome) had greater area with signs of infarction (3.5% vs. 0.6%; p<0.01), a higher density of syncytial knots (p<0.001) and greater proliferation index (p<0.01). Villous vascularity (p<0.001), trophoblast area (p<0.01) and system A activity (p<0.01) were decreased in placentas from RFM compared to controls irrespective of outcome of pregnancy.
CONCLUSIONS:
This study provides evidence of abnormal placental morphology and function in women with RFM and supports the proposition of a causal association between placental insufficiency and RFM. This suggests that women presenting with RFM require further investigation to identify those with placental insufficiency.

PMID 22523561