File:Nephron EM02.jpg - Revision history

Z8600021: /* Glomerulus Podocyte EM */

2019-07-22T04:42:30Z

Glomerulus Podocyte EM

← Older revision		Revision as of 15:42, 22 July 2019
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	==Glomerulus Podocyte EM==		==Glomerulus Podocyte EM==
	An ultrastructural overview of podocytes and the glomerular endothelium.		An ultrastructural overview of podocytes and the glomerular endothelium. SD - slit diaphragm

	(A) Scanning electron micrograph of an exposed glomerulus. In this image, the Bowman’s capsule is broken, permitting a striking view of podocytes (Pod) completely wrapped around the glomerular capillaries.		(A) Scanning electron micrograph of an exposed glomerulus. In this image, the Bowman’s capsule is broken, permitting a striking view of podocytes (Pod) completely wrapped around the glomerular capillaries.
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	(D) Scanning electron micrograph of an exposed glomerular capillary and its numerous perforations (fenestrae). (E) Simplified diagram of the GFB. The GEC and its fenestrae are lined by a filamentous glycocalyx enriched in negatively charged proteoglycans. The glycocalyx and adsorbed plasma components form the thicker ESL. The GBM is a stratified ECM in between podocytes and GECs. Podocytes form the final layer of the GFB. The interdigitating FPs of podocytes are linked by porous SDs where primary urinary filtrate passes through.		(D) Scanning electron micrograph of an exposed glomerular capillary and its numerous perforations (fenestrae). (E) Simplified diagram of the GFB. The GEC and its fenestrae are lined by a filamentous glycocalyx enriched in negatively charged proteoglycans. The glycocalyx and adsorbed plasma components form the thicker ESL. The GBM is a stratified ECM in between podocytes and GECs. Podocytes form the final layer of the GFB. The interdigitating FPs of podocytes are linked by porous slit diaphragms (SDs) where primary urinary filtrate passes through.

Z8600021 at 22:35, 17 Mayıs 2018

2018-05-17T22:35:51Z

← Older revision		Revision as of 09:35, 18 Mayıs 2018
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	~~Figure 2.~~		==Glomerulus Podocyte EM==
	An ultrastructural overview of podocytes and the glomerular endothelium. (A) Scanning electron micrograph of an exposed glomerulus. In this image, the Bowman’s capsule is broken, permitting a striking view of podocytes (Pod) completely wrapped around the glomerular capillaries. (B) Higher magnification of a podocyte within the glomerulus revealing the interdigitated FPs. (C) A resin cast of the glomerular capillary tuft with the cells corroded to reveal its highly convoluted shape. Image courtesy of F. Hossler (East Tennessee State University, Johnson City, TN). (D) Scanning electron micrograph of an exposed glomerular capillary and its numerous perforations (fenestrae). (E) Simplified diagram of the GFB. The GEC and its fenestrae are lined by a filamentous glycocalyx enriched in negatively charged proteoglycans. The glycocalyx and adsorbed plasma components form the thicker ESL. The GBM is a stratified ECM in between podocytes and GECs. Podocytes form the final layer of the GFB. The interdigitating FPs of podocytes are linked by porous SDs where primary urinary filtrate passes through. Bars: (A) 20 µm; (B and D) 1 µm; (C) 50 µm.		An ultrastructural overview of podocytes and the glomerular endothelium.

			(A) Scanning electron micrograph of an exposed glomerulus. In this image, the Bowman’s capsule is broken, permitting a striking view of podocytes (Pod) completely wrapped around the glomerular capillaries.


			(B) Higher magnification of a podocyte within the glomerulus revealing the interdigitated FPs.


			(C) A resin cast of the glomerular capillary tuft with the cells corroded to reveal its highly convoluted shape. Image courtesy of F. Hossler (East Tennessee State University, Johnson City, TN).


			(D) Scanning electron micrograph of an exposed glomerular capillary and its numerous perforations (fenestrae). (E) Simplified diagram of the GFB. The GEC and its fenestrae are lined by a filamentous glycocalyx enriched in negatively charged proteoglycans. The glycocalyx and adsorbed plasma components form the thicker ESL. The GBM is a stratified ECM in between podocytes and GECs. Podocytes form the final layer of the GFB. The interdigitating FPs of podocytes are linked by porous SDs where primary urinary filtrate passes through.


			Bars: (A) 20 µm; (B and D) 1 µm; (C) 50 µm.

			:'''Links:''' [[:File:Nephron EM02.jpg\|colour image version]] \| [[:File:Nephron EM01.jpg\|BW image version]] \| {{renal histology}}

	~~:'''Links:''' {{renal histology}}~~

	===Reference===		===Reference===
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	{{JCB}}		{{JCB}}

	Figure 2. ~~Panel B cropped resized, relabelled and converted to black and white image~~. Text above modified from figure legend.		Figure 2. Relabelled. Text above modified from original figure legend.

	{{Footer}}		{{Footer}}
	[[Category:Renal]]		[[Category:Renal]]
	[[Category:Electron Micrograph]]		[[Category:Electron Micrograph]]

Z8600021: Figure 2. An ultrastructural overview of podocytes and the glomerular endothelium. (A) Scanning electron micrograph of an exposed glomerulus. In this image, the Bowman’s capsule is broken, permitting a striking view of podocytes (Pod) completely wrap...

2018-05-17T22:33:51Z

New page

Figure 2.
An ultrastructural overview of podocytes and the glomerular endothelium. (A) Scanning electron micrograph of an exposed glomerulus. In this image, the Bowman’s capsule is broken, permitting a striking view of podocytes (Pod) completely wrapped around the glomerular capillaries. (B) Higher magnification of a podocyte within the glomerulus revealing the interdigitated FPs. (C) A resin cast of the glomerular capillary tuft with the cells corroded to reveal its highly convoluted shape. Image courtesy of F. Hossler (East Tennessee State University, Johnson City, TN). (D) Scanning electron micrograph of an exposed glomerular capillary and its numerous perforations (fenestrae). (E) Simplified diagram of the GFB. The GEC and its fenestrae are lined by a filamentous glycocalyx enriched in negatively charged proteoglycans. The glycocalyx and adsorbed plasma components form the thicker ESL. The GBM is a stratified ECM in between podocytes and GECs. Podocytes form the final layer of the GFB. The interdigitating FPs of podocytes are linked by porous SDs where primary urinary filtrate passes through. Bars: (A) 20 µm; (B and D) 1 µm; (C) 50 µm.

:'''Links:''' {{renal histology}}

===Reference===
{{#pmid:25918223}}

{{JCB}}

Figure 2. Panel B cropped resized, relabelled and converted to black and white image. Text above modified from figure legend.

{{Footer}}
[[Category:Renal]]
[[Category:Electron Micrograph]]