File:Lymph node structure 02.jpg - Revision history

Z8600021: /* Reference */

2018-04-30T08:39:05Z

Reference

← Older revision		Revision as of 19:39, 30 April 2018
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	===Reference===		===Reference===
	~~<pubmed>~~19644499~~</pubmed>\| [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785037 PMC2785037] \| [http://www.nature.com/nri/journal/v9/n9/abs/nri2588.html Nat Rev Immunol.]~~		{{#pmid:19644499}}

	[http://www.microbiol.unimelb.edu.au/research/immunology/s_mueller.html Mueller]		[http://www.microbiol.unimelb.edu.au/research/immunology/s_mueller.html Mueller]

			====Copyright====
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			{{Footer}}
	[[Category:Immune]]		[[Category:Immune]]

Z8600021 at 11:23, 3 February 2014

2014-02-03T11:23:44Z

← Older revision		Revision as of 22:23, 3 February 2014
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	{{Lymph node cartoons}}		{{Lymph node cartoons}}


	===Reference===		===Reference===
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	[http://www.microbiol.unimelb.edu.au/research/immunology/s_mueller.html Mueller]		[http://www.microbiol.unimelb.edu.au/research/immunology/s_mueller.html Mueller]


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	[[Category:Immune]]		[[Category:Immune]]

Z8600021: /* Lymph Node Structure */

2012-02-25T02:10:00Z

Lymph Node Structure

← Older revision		Revision as of 13:10, 25 February 2012
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	Schematic representation of the organization of a lymph node.		Schematic representation of the organization of a lymph node.
	* '''Afferent lymphatics''' enter lymph nodes and deliver lymph to the subcapsular sinus (SCS), which forms a channel around the periphery of the lymph node.		* '''Afferent lymphatics''' enter lymph nodes and deliver lymph to the '''subcapsular sinus''' (SCS), which forms a channel around the periphery of the lymph node.
	* '''Lymphatic sinuses''' run from the SCS through the cortex to the medulla		* '''Lymphatic sinuses''' run from the SCS through the cortex to the medulla
	* '''Efferent lymphatics''' exit the lymph node via efferent lymphatic vessels on the opposite (hilar) side of the organ.		* '''Efferent lymphatics''' exit the lymph node via efferent lymphatic vessels on the opposite (hilar) side of the organ.

Z8600021: /* Lymph Node Structure */

2012-02-25T02:06:48Z

Lymph Node Structure

← Older revision		Revision as of 13:06, 25 February 2012
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	Schematic representation of the organization of a lymph node.		Schematic representation of the organization of a lymph node.
	* '''Afferent lymphatics''' enter lymph nodes and deliver lymph to the subcapsular sinus (SCS), which forms a channel around the periphery of the lymph node.		* '''Afferent lymphatics''' enter lymph nodes and deliver lymph to the subcapsular sinus (SCS), which forms a channel around the periphery of the lymph node.
	* '''Lymphatic sinuses''' run from the SCS through the cortex to the medulla~~, and~~ exit the lymph node via efferent lymphatic vessels on the opposite, hilar, side of the organ.		* '''Lymphatic sinuses''' run from the SCS through the cortex to the medulla
	* ~~B cell follicles containing follicular dendritic cell~~ (~~FDC~~) ~~networks are arranged~~ in the ~~lymph node cortex~~ and ~~are separated from the SCS by a layer of marginal reticular cells (MRC).~~		* '''Efferent lymphatics''' exit the lymph node via efferent lymphatic vessels on the opposite (hilar) side of the organ.
	* The T cells zones in the paracortex, which contain many fibroblastic reticular cells (FRC), are separated by the cortical ridge, ~~an area rich in T cells, dendritic cells (DCs),~~ blood ~~vessels, and FRC~~.		* '''High endothelial venules''' (HEVs) - in the paracortex and cortical ridge, specialized vessels allow entry of leukocytes from the blood.
	* Blood vessels enter and exit the lymph node on the hilar side, and snake through the lymph node like the branches of a tree.		* Blood vessels enter and exit the lymph node on the hilar side, and snake through the lymph node like the branches of a tree.
	* '''~~High endothelial venules~~''' (~~HEVs~~) - in the paracortex ~~and~~ cortical ridge, ~~specialized~~ vessels ~~allow entry of leukocytes from the blood~~.
			* '''B cell follicles''' containing follicular dendritic cell (FDC) networks are arranged in the lymph node cortex and are separated from the SCS by a layer of marginal reticular cells (MRC).
			* '''T cells zones''' in the paracortex, which contain many fibroblastic reticular cells (FRC), are separated by the cortical ridge, an area rich in T cells, dendritic cells (DCs), blood vessels, and FRC.

Z8600021: /* Lymph Node Structure */

2012-02-25T02:05:21Z

Lymph Node Structure

← Older revision		Revision as of 13:05, 25 February 2012
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	Schematic representation of the organization of a lymph node.		Schematic representation of the organization of a lymph node.
	* Afferent lymphatics enter lymph nodes and deliver lymph to the subcapsular sinus (SCS), which forms a channel around the periphery of the lymph node.		* '''Afferent lymphatics''' enter lymph nodes and deliver lymph to the subcapsular sinus (SCS), which forms a channel around the periphery of the lymph node.
	* Lymphatic sinuses run from the SCS through the cortex to the medulla, and exit the lymph node via efferent lymphatic vessels on the opposite, hilar, side of the organ.		* '''Lymphatic sinuses''' run from the SCS through the cortex to the medulla, and exit the lymph node via efferent lymphatic vessels on the opposite, hilar, side of the organ.
	* B cell follicles containing follicular dendritic cell (FDC) networks are arranged in the lymph node cortex and are separated from the SCS by a layer of marginal reticular cells (MRC).		* B cell follicles containing follicular dendritic cell (FDC) networks are arranged in the lymph node cortex and are separated from the SCS by a layer of marginal reticular cells (MRC).
	* The T cells zones in the paracortex, which contain many fibroblastic reticular cells (FRC), are separated by the cortical ridge, an area rich in T cells, dendritic cells (DCs), blood vessels, and FRC.		* The T cells zones in the paracortex, which contain many fibroblastic reticular cells (FRC), are separated by the cortical ridge, an area rich in T cells, dendritic cells (DCs), blood vessels, and FRC.
	* Blood vessels enter and exit the lymph node on the hilar side, and snake through the lymph node like the branches of a tree.		* Blood vessels enter and exit the lymph node on the hilar side, and snake through the lymph node like the branches of a tree.
	* ~~Specialized high~~ endothelial venules (HEVs) in the paracortex and cortical ridge allow entry of leukocytes from the blood.		* '''High endothelial venules''' (HEVs) - in the paracortex and cortical ridge, specialized vessels allow entry of leukocytes from the blood.

Z8600021 at 02:04, 25 February 2012

2012-02-25T02:04:09Z

← Older revision		Revision as of 13:04, 25 February 2012
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	Scale bars represent 200 μM.		Scale bars represent 200 μM.

			{{Lymph node cartoons}}

	===Reference===		===Reference===

Z8600021: /* Lymph Node Structure */

2012-02-23T15:52:14Z

Lymph Node Structure

← Older revision		Revision as of 02:52, 24 February 2012
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	Schematic representation of the organization of a lymph node.		Schematic representation of the organization of a lymph node.
	* Afferent lymphatics enter lymph nodes and deliver lymph to the subcapsular sinus (SCS), which forms a channel around the periphery of the lymph node.		* Afferent lymphatics enter lymph nodes and deliver lymph to the subcapsular sinus (SCS), which forms a channel around the periphery of the lymph node.
	* Lymphatic sinuses run from the SCS through the cortex to the medulla, and exit the lymph node via efferent lymphatic vessels on the opposite, hilar, side of the organ. * B cell follicles containing follicular dendritic cell (FDC) networks are arranged in the lymph node cortex and are separated from the SCS by a layer of marginal reticular cells (MRC).		* Lymphatic sinuses run from the SCS through the cortex to the medulla, and exit the lymph node via efferent lymphatic vessels on the opposite, hilar, side of the organ.
			* B cell follicles containing follicular dendritic cell (FDC) networks are arranged in the lymph node cortex and are separated from the SCS by a layer of marginal reticular cells (MRC).
	* The T cells zones in the paracortex, which contain many fibroblastic reticular cells (FRC), are separated by the cortical ridge, an area rich in T cells, dendritic cells (DCs), blood vessels, and FRC.		* The T cells zones in the paracortex, which contain many fibroblastic reticular cells (FRC), are separated by the cortical ridge, an area rich in T cells, dendritic cells (DCs), blood vessels, and FRC.
	* Blood vessels enter and exit the lymph node on the hilar side, and snake through the lymph node like the branches of a tree.		* Blood vessels enter and exit the lymph node on the hilar side, and snake through the lymph node like the branches of a tree.

Z8600021 at 15:50, 23 February 2012

2012-02-23T15:50:45Z

← Older revision		Revision as of 02:50, 24 February 2012
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	==Lymph ~~node structure~~==		==Lymph Node Structure==

	Schematic representation of the organization of a lymph node ~~(left panel)~~. Afferent lymphatics enter lymph nodes and deliver lymph to the subcapsular sinus (SCS), which forms a channel around the periphery of the lymph node. Lymphatic sinuses run from the SCS through the cortex to the medulla, and exit the lymph node via efferent lymphatic vessels on the opposite, hilar, side of the organ. B cell follicles containing follicular dendritic cell (FDC) networks are arranged in the lymph node cortex and are separated from the SCS by a layer of marginal reticular cells (MRC). The T cells zones in the paracortex, which contain many fibroblastic reticular cells (FRC), are separated by the cortical ridge, an area rich in T cells, dendritic cells (DCs), blood vessels, and FRC. Blood vessels enter and exit the lymph node on the hilar side, and snake through the lymph node like the branches of a tree. Specialized high endothelial venules (HEVs) in the paracortex and cortical ridge allow entry of leukocytes from the blood. An image of a mouse popliteal lymph node generated using multi-colour immunofluoresence microscopy illustrates the distribution of CD3+ T cells (white), B220+ B cells (blue), CD11c+ DCs (green), LYVE1+ (Lymphatic Vessel Endothelial Receptor 1) lymphatics (cyan), PNAd+ (peripheral node addressin) HEVs (yellow), and ER-TR7+ stromal cells (red) (centre panel). The organization of stromal cells in the lymph node is shown by single-colour immunofluoresence staining for ER-TR7 (right panel).		Schematic representation of the organization of a lymph node.
			* Afferent lymphatics enter lymph nodes and deliver lymph to the subcapsular sinus (SCS), which forms a channel around the periphery of the lymph node.
			* Lymphatic sinuses run from the SCS through the cortex to the medulla, and exit the lymph node via efferent lymphatic vessels on the opposite, hilar, side of the organ. * B cell follicles containing follicular dendritic cell (FDC) networks are arranged in the lymph node cortex and are separated from the SCS by a layer of marginal reticular cells (MRC).
			* The T cells zones in the paracortex, which contain many fibroblastic reticular cells (FRC), are separated by the cortical ridge, an area rich in T cells, dendritic cells (DCs), blood vessels, and FRC.
			* Blood vessels enter and exit the lymph node on the hilar side, and snake through the lymph node like the branches of a tree.
			* Specialized high endothelial venules (HEVs) in the paracortex and cortical ridge allow entry of leukocytes from the blood.

Z8600021 at 15:49, 23 February 2012

2012-02-23T15:49:38Z

← Older revision		Revision as of 02:49, 24 February 2012
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			[[Category:Immune]]

Z8600021 at 08:54, 22 February 2012

2012-02-22T08:54:53Z

← Older revision		Revision as of 19:54, 22 February 2012
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	[http://www.microbiol.unimelb.edu.au/research/immunology/s_mueller.html Mueller]		[http://www.microbiol.unimelb.edu.au/research/immunology/s_mueller.html Mueller]

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