S8600021: ==The changing 3D geometry during limb development== (A) The right hind limb bud at stage E11.0 from the freshly dissected embryo, and (B) a right hind limb bud from another embryo at stage E11.25, 6 h older than (A). (C) The OPT scans were converted i

2010-07-23T01:41:43Z

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==The changing 3D geometry during limb development==

(A) The right hind limb bud at stage E11.0 from the freshly dissected embryo, and (B) a right hind limb bud from another embryo at stage E11.25, 6 h older than (A).

(C) The OPT scans were converted into an iso-surface, a 3D contour of the embryo.

The limb bud shapes St0, (D) and St1 (E) were virtually dissected from the whole-embryo iso-surface.

(F) A comparison between the two empirically measured shapes St0 (white) and St1 (blue) which highlights the shape change over 6 h of development. The main axes are shown anterio-posterior (AP), dorso-ventral (DV), and proximo-distal (PD).

(G) A virtual slice through the fully tetrahedtralised St0 mesh. The surface is discretised with a triangular mesh (green), and the internal mesenchymal volume is discretised with a 3D tetrahedral mesh (red).

Original file name: Figure 2. Journal.pbio.1000420.g002.png

<pubmed>20644711</pubmed>| [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903592/ PMC2903592] | [http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1000420 PLoS]

Copyright: © 2010 Boehm et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

[[Category:Limb]] [[Category:Musculoskeletal]] [[Category:Mouse]] [[Category:Cartoon]]

File:Limb bud growth model 02.jpg - Revision history

S8600021: ==The changing 3D geometry during limb development== (A) The right hind limb bud at stage E11.0 from the freshly dissected embryo, and (B) a right hind limb bud from another embryo at stage E11.25, 6 h older than (A). (C) The OPT scans were converted i