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	<title>File:Intraepithelial lymphocyte differentiation 02.jpg - Revision history</title>
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	<updated>2026-10-20T09:43:34Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://embryology.med.unsw.edu.au/embryology/index.php?title=File:Intraepithelial_lymphocyte_differentiation_02.jpg&amp;diff=172553&amp;oldid=prev</id>
		<title>Z8600021 at 04:18, 26 Ocak 2015</title>
		<link rel="alternate" type="text/html" href="https://embryology.med.unsw.edu.au/embryology/index.php?title=File:Intraepithelial_lymphocyte_differentiation_02.jpg&amp;diff=172553&amp;oldid=prev"/>
		<updated>2015-01-26T04:18:35Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 15:18, 26 Ocak 2015&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l1&quot;&gt;Line 1:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;==Kinetics of the accumulation of natural and induced IELs==&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;==Kinetics of the accumulation of natural and induced IELs==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br/&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br/&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;Natural intraepithelial lymphocytes (IELs) gain their antigen-experienced phenotype and gut-homing capacity in the thymus during their initial agonist-based selection in response to self antigens. They populate the gut compartment early, before environmental antigens have been encountered. Conventional naive T cells differentiate into effector cells in response to peripherally encountered antigens and gradually accumulate over time as antigen- experienced induced IELs in the gut.&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;Natural intraepithelial lymphocytes (IELs) gain their antigen-experienced phenotype and gut-homing capacity in the thymus during their initial agonist-based selection in response to self antigens.  &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt; &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;They populate the gut compartment early, before environmental antigens have been encountered.  &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt; &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;Conventional naive T cells differentiate into effector cells in response to peripherally encountered antigens and gradually accumulate over time as antigen-experienced induced IELs in the gut.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br/&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br/&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br/&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br/&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Z8600021</name></author>
	</entry>
	<entry>
		<id>https://embryology.med.unsw.edu.au/embryology/index.php?title=File:Intraepithelial_lymphocyte_differentiation_02.jpg&amp;diff=172551&amp;oldid=prev</id>
		<title>Z8600021: ==Kinetics of the accumulation of natural and induced IELs==

Natural intraepithelial lymphocytes (IELs) gain their antigen-experienced phenotype and gut-homing capacity in the thymus during their initial agonist-based selection in response to self ant...</title>
		<link rel="alternate" type="text/html" href="https://embryology.med.unsw.edu.au/embryology/index.php?title=File:Intraepithelial_lymphocyte_differentiation_02.jpg&amp;diff=172551&amp;oldid=prev"/>
		<updated>2015-01-26T04:17:29Z</updated>

		<summary type="html">&lt;p&gt;==Kinetics of the accumulation of natural and induced IELs==  Natural intraepithelial lymphocytes (IELs) gain their antigen-experienced phenotype and gut-homing capacity in the thymus during their initial agonist-based selection in response to self ant...&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;==Kinetics of the accumulation of natural and induced IELs==&lt;br /&gt;
&lt;br /&gt;
Natural intraepithelial lymphocytes (IELs) gain their antigen-experienced phenotype and gut-homing capacity in the thymus during their initial agonist-based selection in response to self antigens. They populate the gut compartment early, before environmental antigens have been encountered. Conventional naive T cells differentiate into effector cells in response to peripherally encountered antigens and gradually accumulate over time as antigen- experienced induced IELs in the gut.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
{{Immune Images 2}}&lt;br /&gt;
===Reference===&lt;br /&gt;
&amp;lt;pubmed&amp;gt;21681197&amp;lt;/pubmed&amp;gt;| [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140792 Nat Rev Immunol.]&lt;br /&gt;
&lt;br /&gt;
====Copyright====&lt;br /&gt;
© 2011 Macmillan Publishers Limited. All rights reserved&lt;br /&gt;
&lt;br /&gt;
Licensee: Mark A Hill &lt;br /&gt;
License Date: Jan 25, 2015 &lt;br /&gt;
License Number: 3556220285761 &lt;br /&gt;
Publication: Nature Reviews Immunology &lt;br /&gt;
Title: The light and dark sides of intestinal intraepithelial lymphocytes&lt;br /&gt;
Type Of Use: post on a website Figure 2. &lt;br /&gt;
&lt;br /&gt;
{{Footer}}&lt;br /&gt;
&lt;br /&gt;
[[Category:Immune]] [[Category:Gastrointestinal Tract]][[Category:Cartoon]]&lt;/div&gt;</summary>
		<author><name>Z8600021</name></author>
	</entry>
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