File:Human heart developmental functional networks.jpg - Revision history

Z8600021 at 21:48, 26 November 2018

2018-11-26T21:48:27Z

← Older revision		Revision as of 08:48, 27 November 2018
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	==Human Heart Development Functional Networks==		==Human Heart Development Functional Networks==

	Examples of four functional networks driving the development of different anatomical structures in the human heart.		Examples of four functional networks driving the development of different anatomical structures in the human heart.

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	Tissues affected by the four networks are marked;		Tissues affected by the four networks are marked;

	* AS - developing atrial septum		* AS - developing atrial septum

	* EC - endocardial cushions, which are anatomical precursors to the atrioventricular valves		* EC - endocardial cushions, which are anatomical precursors to the atrioventricular valves

	* VT - developing ventricular trabeculae		* VT - developing ventricular trabeculae

	* OFT - developing outflow tract (mislabeled OTF)		* OFT - developing outflow tract (mislabeled OTF)

	The entire set of 19 networks is shown in detail in Supplementary Figures S1, S2, S3 and S4, and can be downloaded from http://www.cbs.dtu.dk/suppl/dgf/.		The entire set of 19 networks is shown in detail in Supplementary Figures S1, S2, S3 and S4, and can be downloaded from http://www.cbs.dtu.dk/suppl/dgf/.

	~~:'''Links:'''~~

	~~Original file name: Msb201036-f1.jpg~~		{{Heart Links}}

	===Reference===		===Reference===

	~~<pubmed>~~20571530~~</pubmed>\| [http://www.nature.com/msb/journal/v6/n1/full/msb201036.html Mol Syst Biol.]~~		{{#pmid:20571530}}
			====Copyright====
	This is an open-access article distributed under the terms of the Creative Commons Attribution Noncommercial Share Alike 3.0 Unported License, which allows readers to alter, transform, or build upon the article and then distribute the resulting work under the same or similar license to this one. The work must be attributed back to the original author and commercial use is not permitted without specific permission.		This is an open-access article distributed under the terms of the Creative Commons Attribution Noncommercial Share Alike 3.0 Unported License, which allows readers to alter, transform, or build upon the article and then distribute the resulting work under the same or similar license to this one. The work must be attributed back to the original author and commercial use is not permitted without specific permission.

			Original file name: Msb201036-f1.jpg
			{{Footer}}
	[[Category:Human]] [[Category:Heart]] [[Category:Cartoon]] [[Category:Molecular]]		[[Category:Human]] [[Category:Heart]] [[Category:Cartoon]] [[Category:Molecular]]

S8600021 at 04:16, 15 August 2011

2011-08-15T04:16:21Z

← Older revision		Revision as of 15:16, 15 August 2011
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	Examples of four functional networks driving the development of different anatomical structures in the human heart.		Examples of four functional networks driving the development of different anatomical structures in the human heart.

	These four networks constructed by analyzing the interaction patterns of four different sets of cardiac development (CD) proteins corresponding to the morphological groups ‘atrial septal defects,’ ‘abnormal atrioventricular valve morphology,’ ‘abnormal myocardial trabeculae morphology,’ and ‘abnormal outflow tract development’ (Supplementary Table S1). CD proteins from the relevant groups are shown in orange and their interaction partners are shown in gray. Functional modules annotated by literature curation are indicated with a colored background. High-resolution figures (including protein names) can be seen in Supplementary Figures S2A, S2C, S2D, and S3B, respectively. Centrally in the figure is a haematoxylin-eosin stained frontal section of the heart from a 37-day human embryo, where tissues affected by the four networks are marked; AS (developing atrial septum), EC (endocardial cushions, which are anatomical precursors to the atrioventricular valves), VT (developing ventricular trabeculae), and OFT (developing outflow tract). The entire set of 19 networks is shown in detail in Supplementary Figures S1, S2, S3 and S4, and can be downloaded from http://www.cbs.dtu.dk/suppl/dgf/.		These four networks constructed by analyzing the interaction patterns of four different sets of cardiac development (CD) proteins corresponding to the morphological groups ‘atrial septal defects,’ ‘abnormal atrioventricular valve morphology,’ ‘abnormal myocardial trabeculae morphology,’ and ‘abnormal outflow tract development’ (Supplementary Table S1).

	Msb201036-f1.jpg		* CD proteins from the relevant groups are shown in orange and their interaction partners are shown in gray.
			* Functional modules annotated by literature curation are indicated with a colored background.
			* High-resolution figures (including protein names) can be seen in Supplementary Figures S2A, S2C, S2D, and S3B, respectively.
			* Centrally in the figure is a haematoxylin-eosin stained frontal section of the heart from a 37-day human embryo.

			Tissues affected by the four networks are marked;
			* AS - developing atrial septum
			* EC - endocardial cushions, which are anatomical precursors to the atrioventricular valves
			* VT - developing ventricular trabeculae
			* OFT - developing outflow tract (mislabeled OTF)

			The entire set of 19 networks is shown in detail in Supplementary Figures S1, S2, S3 and S4, and can be downloaded from http://www.cbs.dtu.dk/suppl/dgf/.

			:'''Links:'''

			Original file name: Msb201036-f1.jpg

	===Reference===		===Reference===

S8600021 at 04:13, 15 August 2011

2011-08-15T04:13:35Z

← Older revision		Revision as of 15:13, 15 August 2011
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	This is an open-access article distributed under the terms of the Creative Commons Attribution Noncommercial Share Alike 3.0 Unported License, which allows readers to alter, transform, or build upon the article and then distribute the resulting work under the same or similar license to this one. The work must be attributed back to the original author and commercial use is not permitted without specific permission.		This is an open-access article distributed under the terms of the Creative Commons Attribution Noncommercial Share Alike 3.0 Unported License, which allows readers to alter, transform, or build upon the article and then distribute the resulting work under the same or similar license to this one. The work must be attributed back to the original author and commercial use is not permitted without specific permission.


			[[Category:Human]] [[Category:Heart]] [[Category:Cartoon]] [[Category:Molecular]]

S8600021: ==Human Heart Development Functional Networks== Examples of four functional networks driving the development of different anatomical structures in the human heart. These four networks constructed by analyzing the interaction patterns of four different

2011-08-15T04:12:49Z

New page

==Human Heart Development Functional Networks==

Examples of four functional networks driving the development of different anatomical structures in the human heart.

These four networks constructed by analyzing the interaction patterns of four different sets of cardiac development (CD) proteins corresponding to the morphological groups ‘atrial septal defects,’ ‘abnormal atrioventricular valve morphology,’ ‘abnormal myocardial trabeculae morphology,’ and ‘abnormal outflow tract development’ (Supplementary Table S1). CD proteins from the relevant groups are shown in orange and their interaction partners are shown in gray. Functional modules annotated by literature curation are indicated with a colored background. High-resolution figures (including protein names) can be seen in Supplementary Figures S2A, S2C, S2D, and S3B, respectively. Centrally in the figure is a haematoxylin-eosin stained frontal section of the heart from a 37-day human embryo, where tissues affected by the four networks are marked; AS (developing atrial septum), EC (endocardial cushions, which are anatomical precursors to the atrioventricular valves), VT (developing ventricular trabeculae), and OFT (developing outflow tract). The entire set of 19 networks is shown in detail in Supplementary Figures S1, S2, S3 and S4, and can be downloaded from http://www.cbs.dtu.dk/suppl/dgf/.

Msb201036-f1.jpg

===Reference===

<pubmed>20571530</pubmed>| [http://www.nature.com/msb/journal/v6/n1/full/msb201036.html Mol Syst Biol.]

This is an open-access article distributed under the terms of the Creative Commons Attribution Noncommercial Share Alike 3.0 Unported License, which allows readers to alter, transform, or build upon the article and then distribute the resulting work under the same or similar license to this one. The work must be attributed back to the original author and commercial use is not permitted without specific permission.