File:Hair follicle development.jpg - Revision history

S8600021 at 15:12, 20 September 2010

2010-09-20T15:12:50Z

← Older revision		Revision as of 02:12, 21 September 2010
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	Original file name: Nature05574-f1.2.jpg		Original file name: Nature05574-f1.2.jpg
			==Reference==

	~~A single type of progenitor cell maintains normal epidermis. Clayton E, Doupe DP, Klein AM, Winton DJ, Simons BD, Jones PH. Nature. 2007 Mar 8;446(7132):185-9. [http://www.ncbi.nlm.nih.gov~~/pubmed~~/17330052 PMID: 17330052]~~		<pubmed>17330052</pubmed>

	[http://www.hutchison-mrc.cam.ac.uk/Jones.html MRC - Phil Jones Laboratory]		[http://www.hutchison-mrc.cam.ac.uk/Jones.html MRC - Phil Jones Laboratory]

S8600021 at 14:38, 21 April 2010

2010-04-21T14:38:02Z

← Older revision		Revision as of 01:38, 22 April 2010
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	Hair follicles contain stem cells located in the bulge (b, green), with the potential to generate lower hair follicle (lf), sebaceous gland (sg, orange) upper follicle (uf) and interfollicular epidermis (IFE, beige). The schematic shows the organization of keratinocytes in the IFE, as proposed by the stem/TA cell hypothesis. The basal layer comprises stem cells (S, blue), transit amplifying cells (TA, dark green), and post-mitotic basal cells (red), which migrate out of the basal layer as they differentiate (arrows).		Hair follicles contain stem cells located in the bulge (b, green), with the potential to generate lower hair follicle (lf), sebaceous gland (sg, orange) upper follicle (uf) and interfollicular epidermis (IFE, beige). The schematic shows the organization of keratinocytes in the IFE, as proposed by the stem/TA cell hypothesis. The basal layer comprises stem cells (S, blue), transit amplifying cells (TA, dark green), and post-mitotic basal cells (red), which migrate out of the basal layer as they differentiate (arrows).

			Projected Z-stack confocal images of IFE wholemounts from AhcreERT R26EYFP/wt mice viewed from the basal surface at the times shown following induction. Yellow, EYFP; blue, DAPI nuclear stain. Scale bar, 20 microns.


	Original file name: Nature05574-f1.2.jpg		Original file name: Nature05574-f1.2.jpg

S8600021: Organization of the epidermis. Hair follicles contain stem cells located in the bulge (b, green), with the potential to generate lower hair follicle (lf), sebaceous gland (sg, orange) upper follicle (uf) and interfollicular epidermis (IFE, beige). The s

2010-04-21T14:37:15Z

New page

Organization of the epidermis.

Hair follicles contain stem cells located in the bulge (b, green), with the potential to generate lower hair follicle (lf), sebaceous gland (sg, orange) upper follicle (uf) and interfollicular epidermis (IFE, beige). The schematic shows the organization of keratinocytes in the IFE, as proposed by the stem/TA cell hypothesis. The basal layer comprises stem cells (S, blue), transit amplifying cells (TA, dark green), and post-mitotic basal cells (red), which migrate out of the basal layer as they differentiate (arrows).

Original file name: Nature05574-f1.2.jpg

A single type of progenitor cell maintains normal epidermis. Clayton E, Doupe DP, Klein AM, Winton DJ, Simons BD, Jones PH. Nature. 2007 Mar 8;446(7132):185-9. [http://www.ncbi.nlm.nih.gov/pubmed/17330052 PMID: 17330052]

[http://www.hutchison-mrc.cam.ac.uk/Jones.html MRC - Phil Jones Laboratory]

Reprinted by permission from Macmillan Publishers Ltd: Nature. 2007 Mar 8;446(7132):185-9, copyright (2007)

[[Category:Integumentary]] [[Category:Hair]]