Developmental Mechanism - Epithelial Invagination - Revision history

Z8600021 at 02:34, 6 September 2014

2014-09-06T02:34:03Z

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	{{Header}}		{{Header}}

	~~{{Template Page}}~~

	==Introduction==		==Introduction==
	Epithelia during development often undergo folding or invagination. In some cases the epithelial cells are eventually "pinched off" fron the existing epithelia to form a distinct structure, such as a tube or vesicle. For example this process occurs in neural tube formation, sensory placode (otic and optic vesicles). Changes in cell shape require changes in the actin cytoskeleton and recent researh has shown Rho1 a small GTPase of the Rho subfamily (Rho, Rac and Cdc42) which acts as regulatory switch for actin cytoskeleton is activated in epithelial cells for invagination process initiation.		Epithelia during development often undergo folding or invagination. In some cases the epithelial cells are eventually "pinched off" fron the existing epithelia to form a distinct structure, such as a tube or vesicle. For example this process occurs in neural tube formation, sensory placode (otic and optic vesicles). Changes in cell shape require changes in the actin cytoskeleton and recent researh has shown Rho1 a small GTPase of the Rho subfamily (Rho, Rac and Cdc42) which acts as regulatory switch for actin cytoskeleton is activated in epithelial cells for invagination process initiation.
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	{{~~Template:~~Glossary}}		{{Glossary}}

	{{~~Template:~~Footer}}		{{Footer}}

	[[Category:Developmental Mechanism]]		[[Category:Developmental Mechanism]]

Z8600021 at 21:59, 9 July 2014

2014-07-09T21:59:05Z

← Older revision		Revision as of 08:59, 10 July 2014
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	In week 4 ({{GA}} week 6) of human development, on the embryo head region surface ectoderm specialised "patches" (placodes) form associated with later sensory and endocrine development. The first to appear are the paired otic placodes, forming behind the second pharyngeal arch, that invaginate and are eventually lost from the surface. These placodes will form the structures of the [[Hearing_-_Inner_Ear_Development\|inner ear]]. Other sensory placodes, nasal and optic, can be seen slightly later.		In week 4 ({{GA}} week 6) of human development, on the embryo head region surface ectoderm specialised "patches" (placodes) form associated with later sensory and endocrine development. The first to appear are the paired otic placodes, forming behind the second pharyngeal arch, that invaginate and are eventually lost from the surface. These placodes will form the structures of the [[Hearing_-_Inner_Ear_Development\|inner ear]]. Other sensory placodes, nasal and optic, can be seen slightly later.

	[[File:~~Stage11_sem20a~~.jpg\|alt=Human embryo stage 11 electron micrograph otic placode\|\|600px]]		[[File:Stage11_sem20.jpg\|alt=Human embryo stage 11 electron micrograph otic placode\|\|600px]]

	Dorsal view of the early human embryo ([[Carnegie stage 11\|stage 11]]) showing the surface ectoderm otic placode folding to form an indentation on the embryo surface.		Dorsal view of the early human embryo ([[Carnegie stage 11\|stage 11]]) showing the surface ectoderm otic placode folding to form an indentation on the embryo surface.

Z8600021 at 21:47, 9 July 2014

2014-07-09T21:47:22Z

← Older revision		Revision as of 08:47, 10 July 2014
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	<pubmed limit=5>Epithelial Invagination</pubmed>		<pubmed limit=5>Epithelial Invagination</pubmed>
	\|}		\|}
	==Neural ~~plate~~ to Neural Groove==		==Neural Plate to Neural Groove==

	In week 3 ({{GA}} week 5) of human development, the ectodermal '''neural plate''' invaginated to form the '''neural groove'''. This is the first step in converting an epithelial sheet into an epithelial tube that will form the central nervous system.		In week 3 ({{GA}} week 5) of human development, the ectodermal '''neural plate''' invaginated to form the '''neural groove'''. This is the first step in converting an epithelial sheet into an epithelial tube that will form the central nervous system.

	[[File:Stage10_sem6.jpg\|alt=Human embryo stage 10 electron micrograph\|600px]]		[[File:Stage10_sem6.jpg\|alt=Human embryo stage 10 electron micrograph neural plate\|600px]]

			Dorsal view of the early human embryo ([[Carnegie stage 10\|stage 10]]) showing the neural plate folding to form an open groove.

	:'''Links:''' [[Neural System Development]]		:'''Links:''' [[Neural System Development]]

			==Otic Placode to Otic Vesicle==
			In week 4 ({{GA}} week 6) of human development, on the embryo head region surface ectoderm specialised "patches" (placodes) form associated with later sensory and endocrine development. The first to appear are the paired otic placodes, forming behind the second pharyngeal arch, that invaginate and are eventually lost from the surface. These placodes will form the structures of the [[Hearing_-_Inner_Ear_Development\|inner ear]]. Other sensory placodes, nasal and optic, can be seen slightly later.

			[[File:Stage11_sem20a.jpg\|alt=Human embryo stage 11 electron micrograph otic placode\|\|600px]]

			Dorsal view of the early human embryo ([[Carnegie stage 11\|stage 11]]) showing the surface ectoderm otic placode folding to form an indentation on the embryo surface.


			:'''Links:''' [[Placodes]] \| [[Hearing_-_Inner_Ear_Development\|Inner Ear Development]]
	== References ==		== References ==
	<references/>		<references/>

Z8600021 at 21:31, 9 July 2014

2014-07-09T21:31:52Z

← Older revision		Revision as of 08:31, 10 July 2014
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			{{Header}}

	{{Template Page}}		{{Template Page}}

	==Introduction==		==Introduction==
	Epithelia during development often undergo folding or invagination. In some cases the epithelial cells are eventually "pinched off" fron the existing epithelia to form a distinct structure, such as a tube or vesicle. For example this process occurs in neural tube formation, sensory placode (otic and optic vesicles). Changes in cell shape require changes in the actin cytoskeleton and recent researh has shown Rho1 a small GTPase of the Rho subfamily (Rho, Rac and Cdc42) which acts as regulatory switch for actin cytoskeleton is activated in epithelial cells for invagination process initiation.		Epithelia during development often undergo folding or invagination. In some cases the epithelial cells are eventually "pinched off" fron the existing epithelia to form a distinct structure, such as a tube or vesicle. For example this process occurs in neural tube formation, sensory placode (otic and optic vesicles). Changes in cell shape require changes in the actin cytoskeleton and recent researh has shown Rho1 a small GTPase of the Rho subfamily (Rho, Rac and Cdc42) which acts as regulatory switch for actin cytoskeleton is activated in epithelial cells for invagination process initiation.


	<center>'''''Mechanism''' - "a process, technique, or system for achieving a result".''</center>		<center>'''''Mechanism''' - "a process, technique, or system for achieving a result".''</center>


	:{{Mechanism Links}}		{{Mechanism Links}}

	== Some Recent Findings ==		== Some Recent Findings ==
	{\|		{\|
	\|-bgcolor="F5FAFF"		\|-bgcolor="F5FAFF"
	\|		\|
	* <ref><pubmed></pubmed></ref>		* <ref name=PMID><pubmed></pubmed></ref>
	\|}		\|}
			{\| class="wikitable mw-collapsible mw-collapsed"
			! More recent papers
			\|-
			\| [[File:Mark_Hill.jpg\|90px\|left]] {{Most_Recent_Refs}}

			Search term: [http://www.ncbi.nlm.nih.gov/pubmed/?term=Epithelial+Invagination ''Epithelial Invagination'']

			<pubmed limit=5>Epithelial Invagination</pubmed>
			\|}
			==Neural plate to Neural Groove==

			In week 3 ({{GA}} week 5) of human development, the ectodermal '''neural plate''' invaginated to form the '''neural groove'''. This is the first step in converting an epithelial sheet into an epithelial tube that will form the central nervous system.

			[[File:Stage10_sem6.jpg\|alt=Human embryo stage 10 electron micrograph\|600px]]


			:'''Links:''' [[Neural System Development]]
	== References ==		== References ==
	<references/>		<references/>

S8600021: /* Introduction */

2011-11-12T21:51:43Z

Introduction

← Older revision		Revision as of 08:51, 13 November 2011
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	==Introduction==		==Introduction==
	Epithelia during development often undergo folding or invagination~~, such that~~ some of the epithelial cells are "pinched off" fron the existing epithelia to form a distinct structure. For example this process occurs in neural tube formation, sensory placode (otic and optic vesicles). Changes in cell shape require changes in the actin cytoskeleton and recent researh has shown Rho1 a small GTPase of the Rho subfamily (Rho, Rac and Cdc42) which acts as regulatory switch for actin cytoskeleton is activated in epithelial cells for invagination process initiation.		Epithelia during development often undergo folding or invagination. In some cases the epithelial cells are eventually "pinched off" fron the existing epithelia to form a distinct structure, such as a tube or vesicle. For example this process occurs in neural tube formation, sensory placode (otic and optic vesicles). Changes in cell shape require changes in the actin cytoskeleton and recent researh has shown Rho1 a small GTPase of the Rho subfamily (Rho, Rac and Cdc42) which acts as regulatory switch for actin cytoskeleton is activated in epithelial cells for invagination process initiation.

	<center>'''''Mechanism''' - "a process, technique, or system for achieving a result".''</center>		<center>'''''Mechanism''' - "a process, technique, or system for achieving a result".''</center>
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	:{{Mechanism Links}}		:{{Mechanism Links}}


	== Some Recent Findings ==		== Some Recent Findings ==

S8600021: Created page with "{{Template Page}} ==Introduction== Epithelia during development often undergo folding or invagination, such that some of the epithelial cells are "pinched off" fron the existing..."

2011-11-12T21:40:32Z

Created page with "{{Template Page}} ==Introduction== Epithelia during development often undergo folding or invagination, such that some of the epithelial cells are "pinched off" fron the existing..."

New page

{{Template Page}}

==Introduction==
Epithelia during development often undergo folding or invagination, such that some of the epithelial cells are "pinched off" fron the existing epithelia to form a distinct structure. For example this process occurs in neural tube formation, sensory placode (otic and optic vesicles). Changes in cell shape require changes in the actin cytoskeleton and recent researh has shown Rho1 a small GTPase of the Rho subfamily (Rho, Rac and Cdc42) which acts as regulatory switch for actin cytoskeleton is activated in epithelial cells for invagination process initiation.

<center>'''''Mechanism''' - "a process, technique, or system for achieving a result".''</center>

:{{Mechanism Links}}

== Some Recent Findings ==
{|
|-bgcolor="F5FAFF"
|
* <ref><pubmed></pubmed></ref>
|}

== References ==
<references/>

===Textbooks===

===Reviews===
<pubmed></pubmed>

===Articles===

===Search PubMed===

'''Search Pubmed:''' [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=search&term=endocrine%20development Endocrine Development]

==External Links==

{{External Links}}

----

{{Mechanism Links}}

{{Template:Glossary}}

{{Template:Footer}}

[[Category:Developmental Mechanism]]

← Older revision		Revision as of 08:59, 10 July 2014
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	In week 4 ({{GA}} week 6) of human development, on the embryo head region surface ectoderm specialised "patches" (placodes) form associated with later sensory and endocrine development. The first to appear are the paired otic placodes, forming behind the second pharyngeal arch, that invaginate and are eventually lost from the surface. These placodes will form the structures of the [[Hearing_-_Inner_Ear_Development\|inner ear]]. Other sensory placodes, nasal and optic, can be seen slightly later.		In week 4 ({{GA}} week 6) of human development, on the embryo head region surface ectoderm specialised "patches" (placodes) form associated with later sensory and endocrine development. The first to appear are the paired otic placodes, forming behind the second pharyngeal arch, that invaginate and are eventually lost from the surface. These placodes will form the structures of the [[Hearing_-_Inner_Ear_Development\|inner ear]]. Other sensory placodes, nasal and optic, can be seen slightly later.

	[[File:~~Stage11_sem20a~~.jpg\|alt=Human embryo stage 11 electron micrograph otic placode\|\|600px]]		[[File:Stage11_sem20.jpg\|alt=Human embryo stage 11 electron micrograph otic placode\|\|600px]]

	Dorsal view of the early human embryo ([[Carnegie stage 11\|stage 11]]) showing the surface ectoderm otic placode folding to form an indentation on the embryo surface.		Dorsal view of the early human embryo ([[Carnegie stage 11\|stage 11]]) showing the surface ectoderm otic placode folding to form an indentation on the embryo surface.