Category:Carnegie Embryo 670 - Revision history

Z8600021: /* Normal Embryos Over 9 mm Long */

2018-09-24T02:14:03Z

Normal Embryos Over 9 mm Long

← Older revision		Revision as of 13:14, 24 September 2018
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	{{Ref-Mall1915}}		{{Ref-Mall1915}}

	An even more perfect specimen of implantation is possibly that of No. {{CE670}}. The embryo in this case was 12.5 mm. long and the spaces between the chorionic wall and the tube wall are largely empty. There are, however, several hemorrhagic areas about 5 mm. in diameter. Where the villi come in contact with these there is a marked layer of fibrinoid necrosis, a sample of which is shown in plate 2, figure 3. It appears as though this substance may arise from all kinds of tissue, either maternal or embryonal. In the figure just referred to it seems to rise from degenerate trophoblastic cells. In this case we seem to have the reverse of the process shown in No. 109. There the trophoblast is destroying the blood clot. Here the blood clot is surrounding the zone of necrotic tissue which is composed partly of trophoblast. Elsewhere in this specimen are large strands of this fibrinoid substance, which often reach into the tube wall. In general, however, the trophoblast is extremely active and markedly vacuolated. Where the trophoblast is heaped up into large islands, their centers are often necrotic, forming yellow nodules, which in turn are being invaded by vacuolated syncytium. This condition is often seen in uterine implantation and has been described and pictured by Grosser. Undoubtedly we are here dealing with the normal destruction of less-favored villi. Adjacent to one of these masses are several villi, which are being invaded by their own trophoblast. This condition is very pronounced in this specimen and is well illustrated in plate 2, figure 7. In this same figure numerous Hofbauer cells are seen It would seem possible that these Hofbauer cells are free trophoblast cells within the mesoderm of the villus, an opinion already expressed by me in my paper on monsters. As in No. {{CE}}, we have here a beautiful case of successful implantation in the tube. There are but few hemorrhages in the intervillous spaces, the trophoblast is extensive, and the villi appear to be normal. In this case we also have a normal embryo. In contrast with these two specimens, No. 535 contains a normal embryo 11 mm. long, and shows an extensive intervillous hemorrhage. There are some slight changes in this embryo; the branchial arches are partly obliterated, and the body wall is sufficiently transparent to allow the ribs to be seen, so that in all probability the embryo was dead before the tube was removed. In this case the tubal mass is very large, about 55 mm. in diameter, and the tube wall is thick, dense, and hemorrhagic, measuring about 15 mm. Within this hemorrhagic mass all stages of degeneration of villi can be noted; plaques of white necrosis alternate with fresh hemorrhages. Scattered through the mass are strands of leucocytes encircling the ovum that is, at its juncture with the tube wall, a marked infiltration with leucocytes can be noted. The inflammatory process is quite extensive and the necrosis of the villi and its trophoblast is quite complete. We have here an example of the effect of intervillous hemorrhage upon the ovum. It appears to cause its destruction.		An even more perfect specimen of implantation is possibly that of No. {{CE670}}. The embryo in this case was 12.5 mm. long and the spaces between the chorionic wall and the tube wall are largely empty. There are, however, several hemorrhagic areas about 5 mm. in diameter. Where the villi come in contact with these there is a marked layer of fibrinoid necrosis, a sample of which is shown in plate 2, figure 3. It appears as though this substance may arise from all kinds of tissue, either maternal or embryonal. In the figure just referred to it seems to rise from degenerate trophoblastic cells. In this case we seem to have the reverse of the process shown in No. 109. There the trophoblast is destroying the blood clot. Here the blood clot is surrounding the zone of necrotic tissue which is composed partly of trophoblast. Elsewhere in this specimen are large strands of this fibrinoid substance, which often reach into the tube wall. In general, however, the trophoblast is extremely active and markedly vacuolated. Where the trophoblast is heaped up into large islands, their centers are often necrotic, forming yellow nodules, which in turn are being invaded by vacuolated syncytium. This condition is often seen in uterine implantation and has been described and pictured by Grosser. Undoubtedly we are here dealing with the normal destruction of less-favored villi. Adjacent to one of these masses are several villi, which are being invaded by their own trophoblast. This condition is very pronounced in this specimen and is well illustrated in plate 2, figure 7. In this same figure numerous Hofbauer cells are seen It would seem possible that these Hofbauer cells are free trophoblast cells within the mesoderm of the villus, an opinion already expressed by me in my paper on monsters. As in No. {{CE109}}, we have here a beautiful case of successful implantation in the tube. There are but few hemorrhages in the intervillous spaces, the trophoblast is extensive, and the villi appear to be normal. In this case we also have a normal embryo.

Z8600021 at 02:12, 24 September 2018

2018-09-24T02:12:27Z

← Older revision		Revision as of 13:12, 24 September 2018
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	===References===		===References===


			{{Ref-Mall1915}}

			==Normal Embryos Over 9 mm Long==
			[[Book_-_Contributions_to_Embryology_Carnegie_Institution_No.1-3#Normal_Embryos_Over_9_mm_Long\|Normal Embryos Over 9 mm Long]]

			{{Ref-Mall1915}}

			An even more perfect specimen of implantation is possibly that of No. {{CE670}}. The embryo in this case was 12.5 mm. long and the spaces between the chorionic wall and the tube wall are largely empty. There are, however, several hemorrhagic areas about 5 mm. in diameter. Where the villi come in contact with these there is a marked layer of fibrinoid necrosis, a sample of which is shown in plate 2, figure 3. It appears as though this substance may arise from all kinds of tissue, either maternal or embryonal. In the figure just referred to it seems to rise from degenerate trophoblastic cells. In this case we seem to have the reverse of the process shown in No. 109. There the trophoblast is destroying the blood clot. Here the blood clot is surrounding the zone of necrotic tissue which is composed partly of trophoblast. Elsewhere in this specimen are large strands of this fibrinoid substance, which often reach into the tube wall. In general, however, the trophoblast is extremely active and markedly vacuolated. Where the trophoblast is heaped up into large islands, their centers are often necrotic, forming yellow nodules, which in turn are being invaded by vacuolated syncytium. This condition is often seen in uterine implantation and has been described and pictured by Grosser. Undoubtedly we are here dealing with the normal destruction of less-favored villi. Adjacent to one of these masses are several villi, which are being invaded by their own trophoblast. This condition is very pronounced in this specimen and is well illustrated in plate 2, figure 7. In this same figure numerous Hofbauer cells are seen It would seem possible that these Hofbauer cells are free trophoblast cells within the mesoderm of the villus, an opinion already expressed by me in my paper on monsters. As in No. {{CE}}, we have here a beautiful case of successful implantation in the tube. There are but few hemorrhages in the intervillous spaces, the trophoblast is extensive, and the villi appear to be normal. In this case we also have a normal embryo. In contrast with these two specimens, No. 535 contains a normal embryo 11 mm. long, and shows an extensive intervillous hemorrhage. There are some slight changes in this embryo; the branchial arches are partly obliterated, and the body wall is sufficiently transparent to allow the ribs to be seen, so that in all probability the embryo was dead before the tube was removed. In this case the tubal mass is very large, about 55 mm. in diameter, and the tube wall is thick, dense, and hemorrhagic, measuring about 15 mm. Within this hemorrhagic mass all stages of degeneration of villi can be noted; plaques of white necrosis alternate with fresh hemorrhages. Scattered through the mass are strands of leucocytes encircling the ovum that is, at its juncture with the tube wall, a marked infiltration with leucocytes can be noted. The inflammatory process is quite extensive and the necrosis of the villi and its trophoblast is quite complete. We have here an example of the effect of intervillous hemorrhage upon the ovum. It appears to cause its destruction.


	{{Carnegie numbered embryo links}}		{{Carnegie numbered embryo links}}

Z8600021 at 23:21, 19 December 2017

2017-12-19T23:21:10Z

← Older revision		Revision as of 10:21, 20 December 2017
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	{{Carnegie numbered embryo links}}		{{Carnegie numbered embryo links}}

	[[Category:Carnegie Stage 18]]		[[Category:Carnegie Stage 18]][[Category:Week 7]][[Category:Ectopic Pregnancy]]
	[[Category:Week 7]][[Category:1910's]]		[[Category:1910's]]

Z8600021: Created page with "This {{Embryology}} category includes pages and images that relate to the Carnegie Collection Embryo No. {{CE670}} . This embryo was classified as Carnegie stage 18 occur..."

2017-12-19T23:03:44Z

Created page with "This {{Embryology}} category includes pages and images that relate to the Carnegie Collection Embryo No. {{CE670}} . This embryo was classified as Carnegie stage 18 occur..."

New page

This {{Embryology}} category includes pages and images that relate to the Carnegie Collection Embryo No. {{CE670}} . This embryo was classified as [[Carnegie stage 18]] occurring during [[Week 7]].
<br>
{{Carnegie stage 18 links}}
<br>
{| class="wikitable"
|-
! Serial No. !! Size (mm) !! Grade !! Fixative !! Embedding Medium !! Plane !! Thinness (µm) !! Stain !! Semi. ducts !! P.-M. duct (mm) !! Year !! Notes
|-
| {{CE670}} || E, 12.5 || Poor || Ale. || P || {{Sagittal}} || 50 || {{HE}} || 3 || 10 || 1913 || {{Tubal}} Advanced
|}

{{Carnegie Collection stage 18 table}}

===References===

{{Carnegie numbered embryo links}}

[[Category:Carnegie Stage 18]]
[[Category:Week 7]][[Category:1910's]]