Abnormal Development - Salmonella - Revision history

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	~~[[Image:Listeria-bacterium.jpg\|thumb\|Listeria monocytogenes bacteria (Image CDC)]]~~


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	===Textbooks===		===Textbooks===
	'''Medical Microbiology''' - [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=Books&cmd=search&doptcmdl=TOCView&term=~~Listeria~~+AND+mmed%5Bbook%5D Salmonella Search]		'''Medical Microbiology''' - [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=Books&cmd=search&doptcmdl=TOCView&term=Salmonella+AND+mmed%5Bbook%5D Salmonella Search]

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	{{External Links}}		{{External Links}}

			* Australia [https://www.healthdirect.gov.au/salmonella Healthdirect - salmonella]

	* '''Royal College of Obstetricians and Gynaecologists (UK)''' [http://www.rcog.org.uk/index.asp?PageID=307 Infection and Pregnancy - study group recommendations (Jun 2001)]		* '''Royal College of Obstetricians and Gynaecologists (UK)''' [http://www.rcog.org.uk/index.asp?PageID=307 Infection and Pregnancy - study group recommendations (Jun 2001)]

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	* {{#pmid:~~21501460~~\|~~PMID21501460~~}}		* '''Salmonella enterica serovar Enteritidis enterocolitis during late stages of gestation induces an adverse pregnancy outcome in the murine model'''{{#pmid:25365504\|PMID25365504}} "Foodborne diseases caused by Salmonella enterica serovar Enteritidis (S. Enteritidis) are a significant health problem. Pregnancy, state of immunological tolerance, is a predisposing condition for the development of infections with intracellular pathogens. Salmonella species can cause pregnancy complications such as chorioamnionitis, transplacental fetal infection, pre term labor, abortions, neonatal and maternal septicemia. However, the specific mechanisms by which Salmonella infections trigger these alterations are not clear. In the present work, using a self-limiting enterocolitis murine model, we show that the ingestion of a low dose of S. Enteritidis at late stages of pregnancy (day 15 of gestation) is sufficient to induce massive maternal infection. We found that Salmonella infection leads to 40% of pre term delivery, 33% of abortion and fetal growth restriction. Placental dysfunction during S. Enteritidis enterocolitis was confirmed through cellular infiltration and hypoxia markers (MPO activity and COX-1 and COX-2 expression, respectively). Apoptosis in placental tissue due to Salmonella infection was also evident at day 18 of gestation when investigated by morphometric procedure, DNA fragmentation and Fas/FasL expression. Also, the expression of IFN-γ, TNF-α, IL-17 and IL-10 was up regulated in response to Salmonella not only in placenta, but also in amniotic fluid and maternal serum. Altogether, our results demonstrate that S. Enteritidis enterocolitis during late stages of gestation causes detrimental effect on pregnancy outcome."

			* '''Campylobacter, Salmonella, and Yersinia antibodies and pregnancy outcome in Danish women with occupational exposure to animals'''{{#pmid:25245002\|PMID25245002}} "The aim of this study was to determine antibody titres against Campylobacter, Salmonella, and Yersinia in a population-based cohort of pregnant women in Denmark in order to evaluate adverse pregnancy outcomes (miscarriage, preterm birth, and small for gestational age) in relation to occupational exposure to animals in women exposed to food producing animals. METHODS: We used data and blood samples from the Danish National Birth Cohort. Serum samples collected during the first trimester from 192 pregnant women who were occupationally exposed to domestic animals and 188 randomly selected unexposed pregnant women were analysed for IgG, IgM, and IgA antibodies against Campylobacter, Salmonella, and Yersinia. Pregnancy outcomes of interest were identified through the Danish National Patient Register. RESULTS: Women with occupational exposure to animals had significantly higher IgG antibody concentrations against Campylobacter, Salmonella, and Yersinia, whereas they had lower concentrations of IgM and IgA antibodies. CONCLUSIONS: Serological markers were not identified as risk factors for adverse pregnancy outcomes, with the exception of elevated concentrations of Salmonella antibodies, which were found to be associated with an increased risk of preterm birth."

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{{Header}}
{{Educational Warning}}
==Introduction==
[[Image:Listeria-bacterium.jpg|thumb|Listeria monocytogenes bacteria (Image CDC)]]

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{{Bacterial Links}}

==Some Recent Findings==
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* {{#pmid:21501460|PMID21501460}}
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! More recent papers  
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| [[File:Mark_Hill.jpg|90px|left]] {{Most_Recent_Refs}}

Search term: [http://www.ncbi.nlm.nih.gov/pubmed/?term=Salmonella+Pregnancy ''Salmonella Pregnancy'']

<pubmed limit=5>Salmonella Pregnancy</pubmed>
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==Salmonella Infection==

===Lineage===

==References==

<references/>

=== Reviews ===
{{#pmid:21517700}}

=== Articles ===
{{#pmid:20158931}}

===Textbooks===
'''Medical Microbiology''' - [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=Books&cmd=search&doptcmdl=TOCView&term=Listeria+AND+mmed%5Bbook%5D Salmonella Search]

===Search Pubmed===

'''Search PubMed:''' [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=search&term=Congenital+Salmonella Congenital Salmonella] | [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=search&term=Abnormal+Embryology+Salmonella Abnormal Embryology Listeria] | [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=search&term=Abnormal%20Development%20Salmonella Abnormal Development Salmonella]

== External Links ==

{{External Links}}

* '''Royal College of Obstetricians and Gynaecologists (UK)''' [http://www.rcog.org.uk/index.asp?PageID=307 Infection and Pregnancy - study group recommendations (Jun 2001)]

{{Glossary}}

{{Footer}}

[[Category:Abnormal Development]] [[Category:Bacteria]] [[Category:Environmental Abnormalities]]