2011 Lab 3 - Week 4 - Revision history

S8600021: /* Neurogenesis */

2011-08-20T01:54:00Z

Neurogenesis

← Older revision		Revision as of 11:54, 20 August 2011
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	==Neurogenesis==		==Neurogenesis==
	[[File:~~Stage10_SEM1~~.jpg\|thumb\|Neural Groove (stage 10)]]		[[File:Stage10_sem6.jpg\|thumb\|Neural Groove (stage 10)]]
	[[File:Stage12_SEM3.jpg\|thumb\|Caudal Neural Pore (stage 12)]]		[[File:Stage12_SEM3.jpg\|thumb\|Caudal Neural Pore (stage 12)]]

S8600021: /* Neural Patterning */

2011-08-11T00:54:43Z

Neural Patterning

← Older revision		Revision as of 10:54, 11 August 2011
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	==Neural Patterning==		==Neural Patterning==
			Note that patterning signals are reused throughout the embryo to establish to pattern other parts of embryo (see limb development).

	===Rostrocaudal Patterning - Hox===		===Rostrocaudal Patterning - Hox===

S8600021: /* Ventral Patterning - Sonic Hedghog */

2011-08-11T00:53:38Z

Ventral Patterning - Sonic Hedghog

← Older revision		Revision as of 10:53, 11 August 2011
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	This is the classic mutation that gave rise to the discovery of Hox genes and other genes related to body pattern formation. In this mutant during development the fly embryo incorrectly positioned where (antenna) should have be two legs (pedia)<ref name="PMID108157" />. The discovery of this mutant in Walter Gehring's lab opened up the field of developmental genes and this field has been rewarded with the [http://www.nobel.se/laureates/medicine-1995.html 1995 Nobel prize in Medicine].		This is the classic mutation that gave rise to the discovery of Hox genes and other genes related to body pattern formation. In this mutant during development the fly embryo incorrectly positioned where (antenna) should have be two legs (pedia)<ref name="PMID108157" />. The discovery of this mutant in Walter Gehring's lab opened up the field of developmental genes and this field has been rewarded with the [http://www.nobel.se/laureates/medicine-1995.html 1995 Nobel prize in Medicine].

	==Ventral Patterning - Sonic Hedghog==		===Ventral Patterning - Sonic Hedghog===
	[[File:Neural tube - SHH model.jpg\|thumb\|Neural tube - SHH model]]		[[File:Neural tube - SHH model.jpg\|thumb\|Neural tube - SHH model]]
	[[File:Shh frog notochord 1.jpg\|300px]] [[File:Sonic.jpg]]		[[File:Shh frog notochord 1.jpg\|300px]] [[File:Sonic.jpg]]

S8600021: /* Ventral Patterning - Sonic Hedghog */

2011-08-11T00:52:23Z

Ventral Patterning - Sonic Hedghog

← Older revision		Revision as of 10:52, 11 August 2011
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	==Ventral Patterning - Sonic Hedghog==		==Ventral Patterning - Sonic Hedghog==
	[[File:Neural tube - SHH model.jpg\|thumb\|Neural tube - SHH model]]		[[File:Neural tube - SHH model.jpg\|thumb\|Neural tube - SHH model]]
	[[File:Shh frog notochord 1.jpg\|300px]]		[[File:Shh frog notochord 1.jpg\|300px]] [[File:Sonic.jpg]]

	* SHH is secreted by the notochord, ventralizes the neural tube, inducing the floor plate and motor neurons.		* SHH is secreted by the notochord, ventralizes the neural tube, inducing the floor plate and motor neurons.

S8600021: /* Ventral Patterning - Sonic Hedghog */

2011-08-11T00:51:47Z

Ventral Patterning - Sonic Hedghog

← Older revision		Revision as of 10:51, 11 August 2011
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	==Ventral Patterning - Sonic Hedghog==		==Ventral Patterning - Sonic Hedghog==
	[[File:Neural tube - SHH model.jpg\|thumb\|Neural tube - SHH model]]		[[File:Neural tube - SHH model.jpg\|thumb\|Neural tube - SHH model]]
	[[File:Shh frog notochord.jpg\|~~Shh frog notochord~~]]		[[File:Shh frog notochord 1.jpg\|300px]]

	* SHH is secreted by the notochord, ventralizes the neural tube, inducing the floor plate and motor neurons.		* SHH is secreted by the notochord, ventralizes the neural tube, inducing the floor plate and motor neurons.

S8600021: /* Ventral Patterning - Sonic Hedghog */

2011-08-11T00:51:30Z

Ventral Patterning - Sonic Hedghog

← Older revision		Revision as of 10:51, 11 August 2011
Line 76:		Line 76:

	==Ventral Patterning - Sonic Hedghog==		==Ventral Patterning - Sonic Hedghog==
			[[File:Neural tube - SHH model.jpg\|thumb\|Neural tube - SHH model]]
	[[File:~~Shh frog notochord 1~~.jpg\|~~Shh frog notochord~~]] [[File:~~Neural tube - SHH model~~.jpg\|~~300px~~]]		[[File:Shh frog notochord.jpg\|Shh frog notochord]]

	* SHH is secreted by the notochord, ventralizes the neural tube, inducing the floor plate and motor neurons.		* SHH is secreted by the notochord, ventralizes the neural tube, inducing the floor plate and motor neurons.

S8600021: /* Neural Patterning */

2011-08-11T00:50:52Z

Neural Patterning

← Older revision		Revision as of 10:50, 11 August 2011
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	==Neural Patterning==		==Neural Patterning==

	===Rostrocaudal Patterning - Hox ~~Gen~~===		===Rostrocaudal Patterning - Hox===
	{\|		{\|
	\| [[File:Fly_wild-type_head.jpg\|400px]]		\| [[File:Fly_wild-type_head.jpg\|400px]]
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	This is the classic mutation that gave rise to the discovery of Hox genes and other genes related to body pattern formation. In this mutant during development the fly embryo incorrectly positioned where (antenna) should have be two legs (pedia)<ref name="PMID108157" />. The discovery of this mutant in Walter Gehring's lab opened up the field of developmental genes and this field has been rewarded with the [http://www.nobel.se/laureates/medicine-1995.html 1995 Nobel prize in Medicine].		This is the classic mutation that gave rise to the discovery of Hox genes and other genes related to body pattern formation. In this mutant during development the fly embryo incorrectly positioned where (antenna) should have be two legs (pedia)<ref name="PMID108157" />. The discovery of this mutant in Walter Gehring's lab opened up the field of developmental genes and this field has been rewarded with the [http://www.nobel.se/laureates/medicine-1995.html 1995 Nobel prize in Medicine].

			==Ventral Patterning - Sonic Hedghog==

			[[File:Shh frog notochord 1.jpg\|Shh frog notochord]] [[File:Neural tube - SHH model.jpg\|300px]]

			* SHH is secreted by the notochord, ventralizes the neural tube, inducing the floor plate and motor neurons.
			* Regulation of patched by sonic hedgehog in the developing neural tube.<ref><pubmed>8790332</pubmed></ref> "The pattern of PTC expression suggests that Sonic hedgehog may play an inductive role in more dorsal regions of the neural tube than have been previously demonstrated. Examination of the pattern of PTC expression also suggests that PTC may act in a negative feedback loop to attenuate hedgehog signalling."



			:'''Links:''' [[Sonic_hedgehog\|Sonic hedgehog]]

	==Pharyngeal Arches and Placodes==		==Pharyngeal Arches and Placodes==

S8600021: /* Neurall Patterning */

2011-08-11T00:47:46Z

Neurall Patterning

← Older revision		Revision as of 10:47, 11 August 2011
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	[[File:CNS_primary_vesicles.jpg\|300px\|Primary Brain Vesicles]]		[[File:CNS_primary_vesicles.jpg\|300px\|Primary Brain Vesicles]]

	==~~Neurall~~ Patterning==		==Neural Patterning==

	===Rostrocaudal Patterning - Hox Gen===		===Rostrocaudal Patterning - Hox Gen===

S8600021: /* Rostrocaudal Patterning - Hox Genes */

2011-08-11T00:47:38Z

Rostrocaudal Patterning - Hox Genes

← Older revision		Revision as of 10:47, 11 August 2011
Line 62:		Line 62:
	[[File:CNS_primary_vesicles.jpg\|300px\|Primary Brain Vesicles]]		[[File:CNS_primary_vesicles.jpg\|300px\|Primary Brain Vesicles]]

	==~~Rostrocaudal~~ Patterning ~~- Hox Genes~~==		==Neurall Patterning==

			===Rostrocaudal Patterning - Hox Gen===
	{\|		{\|
	\| [[File:Fly_wild-type_head.jpg\|400px]]		\| [[File:Fly_wild-type_head.jpg\|400px]]
Line 73:		Line 74:

	This is the classic mutation that gave rise to the discovery of Hox genes and other genes related to body pattern formation. In this mutant during development the fly embryo incorrectly positioned where (antenna) should have be two legs (pedia)<ref name="PMID108157" />. The discovery of this mutant in Walter Gehring's lab opened up the field of developmental genes and this field has been rewarded with the [http://www.nobel.se/laureates/medicine-1995.html 1995 Nobel prize in Medicine].		This is the classic mutation that gave rise to the discovery of Hox genes and other genes related to body pattern formation. In this mutant during development the fly embryo incorrectly positioned where (antenna) should have be two legs (pedia)<ref name="PMID108157" />. The discovery of this mutant in Walter Gehring's lab opened up the field of developmental genes and this field has been rewarded with the [http://www.nobel.se/laureates/medicine-1995.html 1995 Nobel prize in Medicine].


	==Pharyngeal Arches and Placodes==		==Pharyngeal Arches and Placodes==

S8600021: /* Pharyngeal Arches and Placodes */

2011-08-11T00:46:59Z

Pharyngeal Arches and Placodes

← Older revision		Revision as of 10:46, 11 August 2011
Line 61:		Line 61:

	[[File:CNS_primary_vesicles.jpg\|300px\|Primary Brain Vesicles]]		[[File:CNS_primary_vesicles.jpg\|300px\|Primary Brain Vesicles]]

			==Rostrocaudal Patterning - Hox Genes==

			{\|
			\| [[File:Fly_wild-type_head.jpg\|400px]]
			\| [[File:Fly_antennapedia_head.jpg\|400px]]
			\|-
			\| Fly wild-type head<ref name="PMID108157"><pubmed>108157</pubmed></ref>
			\| Fly antennapedia mutant head<ref name="PMID108157" />
			\|}

			This is the classic mutation that gave rise to the discovery of Hox genes and other genes related to body pattern formation. In this mutant during development the fly embryo incorrectly positioned where (antenna) should have be two legs (pedia)<ref name="PMID108157" />. The discovery of this mutant in Walter Gehring's lab opened up the field of developmental genes and this field has been rewarded with the [http://www.nobel.se/laureates/medicine-1995.html 1995 Nobel prize in Medicine].


	==Pharyngeal Arches and Placodes==		==Pharyngeal Arches and Placodes==