2010 Lecture 7 - Revision history

S8600021: /* Blood flow through the embryo */

2011-08-15T08:37:00Z

Blood flow through the embryo

← Older revision		Revision as of 18:37, 15 August 2011
Line 181:		Line 181:
	Maternal Blood \| -> umbilical vein -> liver -> anastomosis -> sinus venosus -> atria ventricles-> truncus arteriosus -> aortic sac -> aortic arches-> dorsal aorta-> pair of umbilical arteries \| Maternal Blood.		Maternal Blood \| -> umbilical vein -> liver -> anastomosis -> sinus venosus -> atria ventricles-> truncus arteriosus -> aortic sac -> aortic arches-> dorsal aorta-> pair of umbilical arteries \| Maternal Blood.

	[[File:~~Stage13_C7L~~.jpg]]		[[File:Stage_13_image_070.jpg\|600px]]

	'''Low pressure pathway''' [http://embryology.med.unsw.edu.au/Notes/heart3d.htm#venous Stage 13]		'''Low pressure pathway''' [http://embryology.med.unsw.edu.au/Notes/heart3d.htm#venous Stage 13]

S8600021: /* Red blood cells */

2010-08-15T22:23:11Z

Red blood cells

← Older revision		Revision as of 08:23, 16 August 2010
Line 125:		Line 125:

	===Red blood cells===		===Red blood cells===
	The only cells in the blood are nearly entirely fetal red blood cells~~. These cells differ from adult red blood cells in:~~		[[File:Haemoglobin_comparison_oxygen_saturation_curve.png\|thumb\|Red Blood Cell haemoglobin oxygen dissociation curves]]
	* often remaining nucleated.		The only cells in the blood are nearly entirely fetal red blood cells.
	* contain fetal haemoglobin - which has different oxygen and carbon dioxide binding characteristics.

			These cells differ from adult red blood cells in:
			# often remaining nucleated.
			# contain fetal haemoglobin - which has different oxygen and carbon dioxide binding characteristics.

	===Early vascular systems===		===Early vascular systems===

S8600021: /* Angiogenesis */

2010-08-15T22:16:08Z

Angiogenesis

← Older revision		Revision as of 08:16, 16 August 2010
Line 94:		Line 94:
	* Week 37-38 At birth, pressure difference closes foramen ovale leaving a fossa ovalis		* Week 37-38 At birth, pressure difference closes foramen ovale leaving a fossa ovalis

	==~~'''~~Angiogenesis~~'''~~==		==Angiogenesis==

	* Begins week 3 in extraembryonic mesoderm and then embryonic splanchnic mesoderm		* Begins week 3 in extraembryonic mesoderm and then embryonic splanchnic mesoderm

S8600021: /* Development overview */

2010-08-15T22:15:33Z

Development overview

← Older revision		Revision as of 08:15, 16 August 2010
Line 63:		Line 63:
	* Original Notes pages - [http://embryology.med.unsw.edu.au/Notes/heart.htm Introduction] \| [http://embryology.med.unsw.edu.au/Notes/heart2.htm Abnormalities] \| [http://embryology.med.unsw.edu.au/Notes/heart3.htm Stage 13/14] \| [http://embryology.med.unsw.edu.au/Notes/heart4.htm Stage 22] \| [http://embryology.med.unsw.edu.au/Notes/heart5.htm Stage 22 Selected Highpower] \| [http://embryology.med.unsw.edu.au/Notes/heart6.htm Heart] \| [http://embryology.med.unsw.edu.au/Notes/heart8.htm Heart Rate] \| [http://embryology.med.unsw.edu.au/Notes/heart20.htm Blood][http://embryology.med.unsw.edu.au/Notes/heart19.htm Blood Vessels] \| [http://embryology.med.unsw.edu.au/Notes/heart11.htm Molecular] \| [http://embryology.med.unsw.edu.au/Notes/heart31.htm Lymphatic] \| [http://embryology.med.unsw.edu.au/Child/heart.htm Postnatal] \| [http://embryology.med.unsw.edu.au/history/page2b.htm#Harvey History - Harvey]		* Original Notes pages - [http://embryology.med.unsw.edu.au/Notes/heart.htm Introduction] \| [http://embryology.med.unsw.edu.au/Notes/heart2.htm Abnormalities] \| [http://embryology.med.unsw.edu.au/Notes/heart3.htm Stage 13/14] \| [http://embryology.med.unsw.edu.au/Notes/heart4.htm Stage 22] \| [http://embryology.med.unsw.edu.au/Notes/heart5.htm Stage 22 Selected Highpower] \| [http://embryology.med.unsw.edu.au/Notes/heart6.htm Heart] \| [http://embryology.med.unsw.edu.au/Notes/heart8.htm Heart Rate] \| [http://embryology.med.unsw.edu.au/Notes/heart20.htm Blood][http://embryology.med.unsw.edu.au/Notes/heart19.htm Blood Vessels] \| [http://embryology.med.unsw.edu.au/Notes/heart11.htm Molecular] \| [http://embryology.med.unsw.edu.au/Notes/heart31.htm Lymphatic] \| [http://embryology.med.unsw.edu.au/Child/heart.htm Postnatal] \| [http://embryology.med.unsw.edu.au/history/page2b.htm#Harvey History - Harvey]

	== ~~'''~~Development overview~~'''~~ ==		==Development overview==
	[[File:Mouse heart E9.5.jpg\|thumb\|mouse E9.5 heart (stage 10)]]		[[File:Mouse heart E9.5.jpg\|thumb\|mouse E9.5 heart (stage 10)]]
	The heart develops from cardiogenic mesoderm that originally lies above the cranial end of the developing neural tube. Enlargement of the cranial neural fold brings this region ventrally to its correct anatomical position. The original paired cardiac tubes fuse, with the "ventricular" primordia initially lying above the "atria". Growth of the cardiac tube flexes it into an "S-shape" tube, rotating the "ventricles" downward and pushing the "atria" upward.		The heart develops from cardiogenic mesoderm that originally lies above the cranial end of the developing neural tube. Enlargement of the cranial neural fold brings this region ventrally to its correct anatomical position. The original paired cardiac tubes fuse, with the "ventricular" primordia initially lying above the "atria". Growth of the cardiac tube flexes it into an "S-shape" tube, rotating the "ventricles" downward and pushing the "atria" upward.
Line 78:		Line 78:
	\|}		\|}

	===~~'''~~Timecourse~~'''~~===		===Timecourse===

	* forms initially in splanchnic mesoderm of prechordal plate region - cardiogenic region		* forms initially in splanchnic mesoderm of prechordal plate region - cardiogenic region

S8600021: /* Development overview */

2010-08-15T22:12:33Z

Development overview

← Older revision		Revision as of 08:12, 16 August 2010
Line 72:		Line 72:

	[[File:Gray0462.gif\|thumb\|early heart tube]]		[[File:Gray0462.gif\|thumb\|early heart tube]]
	[[File:Human heart SEM1.jpg~~\|frame\|left~~\|The Human Heart from day 10 to 25 (scanning electron micrograph)]]		{\|
			\| [[File:Human heart SEM1.jpg\|The Human Heart from day 10 to 25 (scanning electron micrograph)]]
			\|-
			\| The Human Heart from day 10 to 25 (scanning electron micrograph)
			\|}

	==='''Timecourse'''===		==='''Timecourse'''===

S8600021: /* Development overview */

2010-08-15T22:11:25Z

Development overview

← Older revision		Revision as of 08:11, 16 August 2010
Line 70:		Line 70:


	~~----~~

	[[File:Gray0462.gif\|thumb\|early heart tube]]		[[File:Gray0462.gif\|thumb\|early heart tube]]
Line 76:		Line 75:



	~~----~~

	==='''Timecourse'''===		==='''Timecourse'''===
Line 94:		Line 91:

	* Week 37-38 At birth, pressure difference closes foramen ovale leaving a fossa ovalis		* Week 37-38 At birth, pressure difference closes foramen ovale leaving a fossa ovalis


	=='''Angiogenesis'''==		=='''Angiogenesis'''==

S8600021: /* Cardiovascular Notes */

2010-08-15T22:10:48Z

Cardiovascular Notes

← Older revision		Revision as of 08:10, 16 August 2010
Line 61:		Line 61:
	* [[Cardiovascular System Development]]		* [[Cardiovascular System Development]]
	* [[Cardiac_Embryology\|Cardiac Embryology Tutorial]] - [[Basic Cardiac Embryology]] \| [[Intermediate Cardiac Embryology]] [[Advanced Cardiac Embryology]]		* [[Cardiac_Embryology\|Cardiac Embryology Tutorial]] - [[Basic Cardiac Embryology]] \| [[Intermediate Cardiac Embryology]] [[Advanced Cardiac Embryology]]
	* Original Notes pages - [http://embryology.med.unsw.edu.au/Notes/heart.htm Introduction] \| [http://embryology.med.unsw.edu.au/Notes/heart2.htm Abnormalities] \| [http://embryology.med.unsw.edu.au/Notes/heart3.htm Stage 13/14] \| [http://embryology.med.unsw.edu.au/Notes/heart4.htm Stage 22] \| [http://embryology.med.unsw.edu.au/Notes/heart5.htm Stage 22 Selected Highpower] \| [http://embryology.med.unsw.edu.au/Notes/heart6.htm Heart] \| [http://embryology.med.unsw.edu.au/Notes/heart8.htm Heart Rate] \| [http://embryology.med.unsw.edu.au/Notes/heart20.htm Blood][http://embryology.med.unsw.edu.au/Notes/heart19.htm Blood Vessels] \| [http://embryology.med.unsw.edu.au/Notes/heart11.htm Molecular] \| [http://embryology.med.unsw.edu.au/Notes/heart31.htm Lymphatic~~] \| [http://embryology.med.unsw.edu.au/Notes/hearttxt.htm Text only page] \| [http://embryology.med.unsw.edu.au/Notes/heartlink.htm WWW Links~~] \| [http://embryology.med.unsw.edu.au/Child/heart.htm Postnatal] \| [http://embryology.med.unsw.edu.au/history/page2b.htm#Harvey History - Harvey]		* Original Notes pages - [http://embryology.med.unsw.edu.au/Notes/heart.htm Introduction] \| [http://embryology.med.unsw.edu.au/Notes/heart2.htm Abnormalities] \| [http://embryology.med.unsw.edu.au/Notes/heart3.htm Stage 13/14] \| [http://embryology.med.unsw.edu.au/Notes/heart4.htm Stage 22] \| [http://embryology.med.unsw.edu.au/Notes/heart5.htm Stage 22 Selected Highpower] \| [http://embryology.med.unsw.edu.au/Notes/heart6.htm Heart] \| [http://embryology.med.unsw.edu.au/Notes/heart8.htm Heart Rate] \| [http://embryology.med.unsw.edu.au/Notes/heart20.htm Blood][http://embryology.med.unsw.edu.au/Notes/heart19.htm Blood Vessels] \| [http://embryology.med.unsw.edu.au/Notes/heart11.htm Molecular] \| [http://embryology.med.unsw.edu.au/Notes/heart31.htm Lymphatic] \| [http://embryology.med.unsw.edu.au/Child/heart.htm Postnatal] \| [http://embryology.med.unsw.edu.au/history/page2b.htm#Harvey History - Harvey]

	== '''Development overview''' ==		== '''Development overview''' ==

S8600021: /* UNSW Embryology Links */

2010-08-15T22:09:58Z

UNSW Embryology Links

← Older revision		Revision as of 08:09, 16 August 2010
Line 37:		Line 37:
	==UNSW Embryology Links==		==UNSW Embryology Links==

	* '''Cardiovascular Slides''' [http://embryology.med.unsw.edu.au/Science/ANAT2341lecture07.htm Cardiovasular Lecture 7 2008] \| [http://embryology.med.unsw.edu.au/pdf/ANAT2341L07Hearts1.pdf Heart Lecture 2008 - 1 slide/page ] \| [http://embryology.med.unsw.edu.au/pdf/ANAT2341L07Hearts4.pdf Heart Lecture 2008 Slides - 4 slides/page] \| [http://embryology.med.unsw.edu.au/pdf/ANAT2341L07Hearts6.pdf Heart Lecture 2008 Slides - 6 slides/page]		====Cardiovascular Slides====
	* ~~'''Cardiovascular Movies'''~~ [~~http://embryology.med.unsw.edu.au/Movies/heart.htm Heart Movies] \|~~ [~~http://embryology.med.unsw.edu.au//Movies/larsen/looping.mov Heart Looping]~~ \| [http://embryology.med.unsw.edu.au//Movies/larsen/atrium.mov Atrial Septation] \| [http://embryology.med.unsw.edu.au//Movies/larsen/avc.mov Realignment] \| [http://embryology.med.unsw.edu.au//Movies/larsen/ventricl.mov Ventricular Septation] ~~\| [http://embryology.med.unsw.edu.au/Movies/heart.htm#HeartSeptation Heart Septation Models~~] \| [http://embryology.med.unsw.edu.au/~~Movies~~/~~heart~~.htm~~#HistoricHeart Historic Heart Movie~~] \|		* [[2010_Lecture_7\|2009 Lecture]] \| [http://embryology.med.unsw.edu.au/Science/ANAT2341lecture07.htm 2008 Lecture]

	* '''Cardiovascular Notes''' [http://embryology.med.unsw.edu.au/Notes/heart.htm Introduction] \| [http://embryology.med.unsw.edu.au/Notes/heart2.htm Abnormalities] \| [http://embryology.med.unsw.edu.au/Notes/heart3.htm Stage 13/14] \| [http://embryology.med.unsw.edu.au/Notes/heart4.htm Stage 22] \| [http://embryology.med.unsw.edu.au/Notes/heart5.htm Stage 22 Selected Highpower] \| [http://embryology.med.unsw.edu.au/Notes/heart6.htm Heart] \| [http://embryology.med.unsw.edu.au/Notes/heart8.htm Heart Rate] \| [http://embryology.med.unsw.edu.au/Notes/heart20.htm Blood][http://embryology.med.unsw.edu.au/Notes/heart19.htm Blood Vessels] \| [http://embryology.med.unsw.edu.au/Notes/heart11.htm Molecular] \| [http://embryology.med.unsw.edu.au/Notes/heart31.htm Lymphatic] \| [http://embryology.med.unsw.edu.au/Notes/hearttxt.htm Text only page] \| [http://embryology.med.unsw.edu.au/Notes/heartlink.htm WWW Links] \| [http://embryology.med.unsw.edu.au/Child/heart.htm Postnatal] \| [http://embryology.med.unsw.edu.au/history/page2b.htm#Harvey History - Harvey]		====Cardiovascular Movies====

			{\| border='0px'

			\|-
			\| [[File:Heart1_looping icon.jpg\|90px\|link=Development_Animation_-_Heart Looping]]
			\| [[File:Heart1_realign icon.jpg\|90px\|link=Development_Animation_-_Heart Realign]]
			\| [[File:Heart1_atrium icon.jpg\|90px\|link=Development_Animation_-_Heart Atrial Septation]]
			\| [[File:heart1 ventricle icon.jpg\|90px\|link=Development_Animation_-_Heart Outflow Septation]]
			\|-
			\| [[Development_Animation_-_Heart Looping\|Heart Looping]]
			\| [[Development_Animation_-_Heart Realign\|Heart Realign]]
			\| [[Development_Animation_-_Heart Atrial Septation\|Heart Atrial Septation]]
			\| [[Development_Animation_-_Heart Outflow Septation\|Heart Outflow Septation]]
			\|-
			\|}

			====Cardiovascular Notes====

			* [[Cardiovascular System Development]]
			* [[Cardiac_Embryology\|Cardiac Embryology Tutorial]] - [[Basic Cardiac Embryology]] \| [[Intermediate Cardiac Embryology]] [[Advanced Cardiac Embryology]]
			* Original Notes pages - [http://embryology.med.unsw.edu.au/Notes/heart.htm Introduction] \| [http://embryology.med.unsw.edu.au/Notes/heart2.htm Abnormalities] \| [http://embryology.med.unsw.edu.au/Notes/heart3.htm Stage 13/14] \| [http://embryology.med.unsw.edu.au/Notes/heart4.htm Stage 22] \| [http://embryology.med.unsw.edu.au/Notes/heart5.htm Stage 22 Selected Highpower] \| [http://embryology.med.unsw.edu.au/Notes/heart6.htm Heart] \| [http://embryology.med.unsw.edu.au/Notes/heart8.htm Heart Rate] \| [http://embryology.med.unsw.edu.au/Notes/heart20.htm Blood][http://embryology.med.unsw.edu.au/Notes/heart19.htm Blood Vessels] \| [http://embryology.med.unsw.edu.au/Notes/heart11.htm Molecular] \| [http://embryology.med.unsw.edu.au/Notes/heart31.htm Lymphatic] \| [http://embryology.med.unsw.edu.au/Notes/hearttxt.htm Text only page] \| [http://embryology.med.unsw.edu.au/Notes/heartlink.htm WWW Links] \| [http://embryology.med.unsw.edu.au/Child/heart.htm Postnatal] \| [http://embryology.med.unsw.edu.au/history/page2b.htm#Harvey History - Harvey]

	== '''Development overview''' ==		== '''Development overview''' ==

S8600021: /* Textbook references */

2010-08-15T22:04:58Z

Textbook references

← Older revision		Revision as of 08:04, 16 August 2010
Line 24:		Line 24:
	* The Developing Human: Clinically Oriented Embryology (6th ed.) Chapter 14: p304-349		* The Developing Human: Clinically Oriented Embryology (6th ed.) Chapter 14: p304-349

	~~'''~~Other ~~textbooks'''~~		===Other Textbooks===
	* Before we Are Born (5th ed.) Moore and Persaud Chapter 12; p241-254		* Before we Are Born (5th ed.) Moore and Persaud Chapter 12; p241-254
	* Essentials of Human Embryology Larson Chapter 7 p97-122 Heart, Chapter 8 p123-146 Vasculature		* Essentials of Human Embryology Larson Chapter 7 p97-122 Heart, Chapter 8 p123-146 Vasculature
	* Human Embryology Fitzgerald and Fitzgerald Chapter 13-17: p77-111		* Human Embryology Fitzgerald and Fitzgerald Chapter 13-17: p77-111

	~~'''~~Recent ~~reviews'''~~		===Recent Reviews===
	<pubmed>11891982</pubmed>		<pubmed>11891982</pubmed>
	<pubmed>12746463</pubmed>		<pubmed>12746463</pubmed>

S8600021: /* Textbook references */

2010-08-15T22:04:18Z

Textbook references

← Older revision		Revision as of 08:04, 16 August 2010
Line 30:		Line 30:

	'''Recent reviews'''		'''Recent reviews'''
	* Yutzey KE, Kirby ML. Wherefore heart thou? Embryonic origins of cardiogenic mesoderm. Dev Dyn. 2002 Mar;223(3):307-20. Review. [http://www.ncbi.nlm.nih.gov/pubmed~~/11891982?dopt=Abstract PMID: 11891982]~~		<pubmed>11891982</pubmed>
	* Three-dimensional reconstruction of gene expression patterns during cardiac development. Soufan AT, Ruijter JM, van den Hoff MJ, de Boer PA, Hagoort J, Moorman AF. Physiol Genomics. 2003 May 13;13(3):187-95. Review. [http://www.ncbi.nlm.nih.gov/pubmed~~/12746463 PMID: 12746463]~~		<pubmed>12746463</pubmed>
	* Moorman A, Webb S, Brown NA, Lamers W, Anderson RH. Development of the heart: (1) formation of the cardiac chambers and arterial trunks. Heart. 2003 Jul;89(7):806-14. [http://www.ncbi.nlm.nih.gov/pubmed~~/12807866?dopt=Abstract PMID: 12807866]~~		<pubmed>12807866</pubmed>
	* Bruneau BG. Transcriptional regulation of vertebrate cardiac morphogenesis. Circ Res. 2002 Mar 22;90(5):509-19. Review. [http://www.ncbi.nlm.nih.gov/pubmed~~/11909814?dopt=Abstract PMID: 11909814]~~		<pubmed>11909814</pubmed>

	==UNSW Embryology Links==		==UNSW Embryology Links==