2010 Lecture 12 - Revision history

S8600021: /* Abnormalities */

2010-09-01T02:45:24Z

Abnormalities

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	[[File:Childhood cancer survival rates.jpg\|thumb\|Childhood cancer survival rates]]		[[File:Childhood cancer survival rates.jpg\|thumb\|Childhood cancer survival rates]]

	[http://www.ncbi.nlm.nih.gov/~~entrez~~/~~dispomim.cgi?id=~~256700 OMIM - Neuroblastoma]		[http://www.ncbi.nlm.nih.gov/omim/256700 OMIM - Neuroblastoma]

	===Digeorge Syndrome (DGS)===		===Digeorge Syndrome (DGS)===

S8600021: /* Historic Migration Experiments */

2010-09-01T02:19:40Z

Historic Migration Experiments

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	==Historic Migration Experiments==		==Historic Migration Experiments==
	Key early experiments in understanding the pattern of neural crest migration were carried out by LeDouarin in the 1980's (see Development of the peripheral Nervous system from the neural crest, Ann Rev Cell Biol 4 p375)		Key early experiments in understanding the pattern of neural crest migration were carried out by [[Embryology_History_-_Nicole_Le_Douarin\|LeDouarin]] in the 1980's (see Development of the peripheral Nervous system from the neural crest, Ann Rev Cell Biol 4 p375)
	[http://www.sdbonline.org/archive/dbcinema/ledouarin/ledouarin.html Quail-Chick Chimeras] \| [http://www.ncbi.nlm.nih.gov/books/bv.fcgi?&rid=dbio.figgrp.63 Figure 1.11. Neural crest cell migration Chimera experiment]		[http://www.sdbonline.org/archive/dbcinema/ledouarin/ledouarin.html Quail-Chick Chimeras] \| [http://www.ncbi.nlm.nih.gov/books/bv.fcgi?&rid=dbio.figgrp.63 Figure 1.11. Neural crest cell migration Chimera experiment]

S8600021: /* Historic Migration Experiments */

2010-09-01T02:17:38Z

Historic Migration Experiments

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	[http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=eurekah&part=A63004&rendertype=figure&id=A63009 Figure 1. Diagram of an E10 embryo showing the origins of neural crest cells that colonize the developing gastrointestinal tract]		[http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=eurekah&part=A63004&rendertype=figure&id=A63009 Figure 1. Diagram of an E10 embryo showing the origins of neural crest cells that colonize the developing gastrointestinal tract]

	===Historic Migration Experiments===		==Historic Migration Experiments==
	Key early experiments in understanding the pattern of neural crest migration were carried out by LeDouarin in the 1980's (see Development of the peripheral Nervous system from the neural crest, Ann Rev Cell Biol 4 p375)		Key early experiments in understanding the pattern of neural crest migration were carried out by LeDouarin in the 1980's (see Development of the peripheral Nervous system from the neural crest, Ann Rev Cell Biol 4 p375)
	[http://www.sdbonline.org/archive/dbcinema/ledouarin/ledouarin.html Quail-Chick Chimeras] \| [http://www.ncbi.nlm.nih.gov/books/bv.fcgi?&rid=dbio.figgrp.63 Figure 1.11. Neural crest cell migration Chimera experiment]		[http://www.sdbonline.org/archive/dbcinema/ledouarin/ledouarin.html Quail-Chick Chimeras] \| [http://www.ncbi.nlm.nih.gov/books/bv.fcgi?&rid=dbio.figgrp.63 Figure 1.11. Neural crest cell migration Chimera experiment]

S8600021: /* Trunk */

2010-09-01T02:16:58Z

Trunk

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	[[File:Mouse_head_E9-neural_crest_GFP.jpg\|300px\|\|Mouse_head_E9-neural_crest_GFP]] [[File:Hindbrain neural crest migration.jpg\|300px\|Hindbrain neural crest migration]] [[File:Mouse-E9.5-Sox10.jpg\|300px\|Mouse-E9.5-Sox10.jpg]]		[[File:Mouse_head_E9-neural_crest_GFP.jpg\|300px\|\|Mouse_head_E9-neural_crest_GFP]] [[File:Hindbrain neural crest migration.jpg\|300px\|Hindbrain neural crest migration]] [[File:Mouse-E9.5-Sox10.jpg\|300px\|Mouse-E9.5-Sox10.jpg]]
	===Trunk===		===Trunk===

			===Cardiac Outflow Tract===

	[[File:Cardiac_Neural_Crest_Migration.jpg\|300px]]		[[File:Cardiac_Neural_Crest_Migration.jpg\|300px]]

S8600021: /* Trunk */

2010-09-01T02:16:22Z

Trunk

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	[[File:Mouse_head_E9-neural_crest_GFP.jpg\|300px\|\|Mouse_head_E9-neural_crest_GFP]] [[File:Hindbrain neural crest migration.jpg\|300px\|Hindbrain neural crest migration]] [[File:Mouse-E9.5-Sox10.jpg\|300px\|Mouse-E9.5-Sox10.jpg]]		[[File:Mouse_head_E9-neural_crest_GFP.jpg\|300px\|\|Mouse_head_E9-neural_crest_GFP]] [[File:Hindbrain neural crest migration.jpg\|300px\|Hindbrain neural crest migration]] [[File:Mouse-E9.5-Sox10.jpg\|300px\|Mouse-E9.5-Sox10.jpg]]
	===Trunk===		===Trunk===
	[[File:Cardiac_Neural_Crest_Migration.jpg]]		[[File:Cardiac_Neural_Crest_Migration.jpg\|300px]]

	[[File:Human neural crest cell migration-in vitro.jpg\|thumb\|Human neural crest cell migration (in vitro)<ref><pubmed>18689800</pubmed>\| [http://hmg.oxfordjournals.org/cgi/content/full/17/21/3411 Hum Mol Genet.]</ref>]]		[[File:Human neural crest cell migration-in vitro.jpg\|thumb\|Human neural crest cell migration (in vitro)<ref><pubmed>18689800</pubmed>\| [http://hmg.oxfordjournals.org/cgi/content/full/17/21/3411 Hum Mol Genet.]</ref>]]

S8600021: /* Trunk */

2010-09-01T02:15:37Z

Trunk

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	[[File:Mouse_head_E9-neural_crest_GFP.jpg\|300px\|\|Mouse_head_E9-neural_crest_GFP]] [[File:Hindbrain neural crest migration.jpg\|300px\|Hindbrain neural crest migration]] [[File:Mouse-E9.5-Sox10.jpg\|300px\|Mouse-E9.5-Sox10.jpg]]		[[File:Mouse_head_E9-neural_crest_GFP.jpg\|300px\|\|Mouse_head_E9-neural_crest_GFP]] [[File:Hindbrain neural crest migration.jpg\|300px\|Hindbrain neural crest migration]] [[File:Mouse-E9.5-Sox10.jpg\|300px\|Mouse-E9.5-Sox10.jpg]]
	===Trunk===		===Trunk===
			[[File:Cardiac_Neural_Crest_Migration.jpg]]

	[[File:Human neural crest cell migration-in vitro.jpg\|thumb\|Human neural crest cell migration (in vitro)<ref><pubmed>18689800</pubmed>\| [http://hmg.oxfordjournals.org/cgi/content/full/17/21/3411 Hum Mol Genet.]</ref>]]		[[File:Human neural crest cell migration-in vitro.jpg\|thumb\|Human neural crest cell migration (in vitro)<ref><pubmed>18689800</pubmed>\| [http://hmg.oxfordjournals.org/cgi/content/full/17/21/3411 Hum Mol Genet.]</ref>]]
	[http://www.ncbi.nlm.nih.gov/books/bv.fcgi?&rid=dbio.figgrp.3118 Figure 13.2. Neural crest cell migration in the trunk of the chick embryo]		[http://www.ncbi.nlm.nih.gov/books/bv.fcgi?&rid=dbio.figgrp.3118 Figure 13.2. Neural crest cell migration in the trunk of the chick embryo]

S8600021: /* Teacher Collins syndrome */

2010-09-01T00:00:04Z

Teacher Collins syndrome

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	Cardiac abnormality possibly stemming from abnormal [[N#neural crest\|neural crest]] migration. Named after Etienne-Louis Arthur Fallot (1888) who described it as "''la maladie blue''". (More? [[Cardiovascular System Development]] \| [[Cardiac_Embryology\|Cardiac Tutorial]] \| [[2009_Lecture_21\|Lecture - Heart]] \| [http://embryology.med.unsw.edu.au/Notes/heart2.htm#Fallot Heart Abnormalities])		Cardiac abnormality possibly stemming from abnormal [[N#neural crest\|neural crest]] migration. Named after Etienne-Louis Arthur Fallot (1888) who described it as "''la maladie blue''". (More? [[Cardiovascular System Development]] \| [[Cardiac_Embryology\|Cardiac Tutorial]] \| [[2009_Lecture_21\|Lecture - Heart]] \| [http://embryology.med.unsw.edu.au/Notes/heart2.htm#Fallot Heart Abnormalities])

	==~~Teacher~~ Collins syndrome==		===Treacher Collins syndrome===

			(TCS) A genetic developmental abnormality results from autosomal dominant mutations of the gene TCOF1 encoding the protein Treacle, identified in [http://www.ncbi.nlm.nih.gov/pubmed/8563749 2006]. The syndrome is characterized by hypoplasia of the facial bones, cleft palate, and middle and external ear defects. These defects may relate to the effects on neural crest migration. (More? [[Neural Crest Development]] \| [http://www.ncbi.nlm.nih.gov/omim/606847 OMIM - TCOF1] \| [http://www.ncbi.nlm.nih.gov/pubmed/8563749 PMID: 8563749])

	== References ==		== References ==

S8600021: /* tetralogy of Fallot */

2010-08-31T23:59:45Z

tetralogy of Fallot

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	[http://atlasgeneticsoncology.org/Tumors/NeurofibromaID5098.html Atlas of Genetics and Cytogenetics in Oncology- Neurofibroma]		[http://atlasgeneticsoncology.org/Tumors/NeurofibromaID5098.html Atlas of Genetics and Cytogenetics in Oncology- Neurofibroma]

	===~~tetralogy~~ of Fallot===		===Tetralogy of Fallot===
	Cardiac abnormality possibly stemming from abnormal [[N#neural crest\|neural crest]] migration. Named after Etienne-Louis Arthur Fallot (1888) who described it as "''la maladie blue''". (More? [[Cardiovascular System Development]] \| [[Cardiac_Embryology\|Cardiac Tutorial]] \| [[2009_Lecture_21\|Lecture - Heart]] \| [http://embryology.med.unsw.edu.au/Notes/heart2.htm#Fallot Heart Abnormalities])		Cardiac abnormality possibly stemming from abnormal [[N#neural crest\|neural crest]] migration. Named after Etienne-Louis Arthur Fallot (1888) who described it as "''la maladie blue''". (More? [[Cardiovascular System Development]] \| [[Cardiac_Embryology\|Cardiac Tutorial]] \| [[2009_Lecture_21\|Lecture - Heart]] \| [http://embryology.med.unsw.edu.au/Notes/heart2.htm#Fallot Heart Abnormalities])


	==Teacher Collins syndrome==		==Teacher Collins syndrome==

S8600021: /* Abnormalities */

2010-08-31T23:59:10Z

Abnormalities

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	[http://atlasgeneticsoncology.org/Tumors/NeurofibromaID5098.html Atlas of Genetics and Cytogenetics in Oncology- Neurofibroma]		[http://atlasgeneticsoncology.org/Tumors/NeurofibromaID5098.html Atlas of Genetics and Cytogenetics in Oncology- Neurofibroma]

			===tetralogy of Fallot===
			Cardiac abnormality possibly stemming from abnormal [[N#neural crest\|neural crest]] migration. Named after Etienne-Louis Arthur Fallot (1888) who described it as "''la maladie blue''". (More? [[Cardiovascular System Development]] \| [[Cardiac_Embryology\|Cardiac Tutorial]] \| [[2009_Lecture_21\|Lecture - Heart]] \| [http://embryology.med.unsw.edu.au/Notes/heart2.htm#Fallot Heart Abnormalities])


			==Teacher Collins syndrome==

	== References ==		== References ==

S8600021 at 23:56, 31 August 2010

2010-08-31T23:56:32Z

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	<div style="background:#F5FFFA; border: 1px solid #CEF2E0; padding: 1em; margin: auto; width: 95%; float:left;"><div style="margin:0;background-color:#cef2e0;font-family:sans-serif;font-size:120%;font-weight:bold;border:1px solid #a3bfb1;text-align:left;color:#000;padding-left:0.4em;padding-top:0.2em;padding-bottom:0.2em;">Lecture Notice - Mark Hill</div>This online lecture page will contain the content required when attending the lecture. Currently this page is only a template and will be updated before the lecture (this notice removed when completed). Final lecture pages can also be printed out using the "printable version" lefthand menu.</div>

	= Neural Crest Development=		= Neural Crest Development=
	== Introduction ==		== Introduction ==