Peer Assessment assignment:
Mark Hill (talk) 10:20, 11 October 2018 (AEDT) This peer assessment is very good in that you have briefly identified both positive and negative aspects of each project as they currently exist. In addition you have used appropriate feedback language that is useful for each group to develop a better project page. Well done.
Group 1, Adrenal Medulla: The History section is very detailed - more weight on the history of neural crest discovery related to the adrenal medulla specifically would be appreciated, as this is your topic, but I do think that it is good that you have maintained a focus on neural crest.
I think your section on genes and transcription factors is well described - I like that you have given a mouse model example. I presume the links to the sites will be added as proper references later. I also think the image of the cascade of catecholamine synthesis is helpful for those interested in the pathway, though its location is currently too far away from this section on the page. However, this is a minor issue and something that might be tidied up nearer the end of the assignment.
You currently don’t have any abnormalities/abnormal development information. It would be nice to see some example here such as Congenital Adrenal Hyperplasia.
In “current research” you have copied and pasted the introduction from the article cited. This definitely needs to be put into your own words, and maybe simplified as currently it is quite difficult to understand.
Group 4, Cardiac:
You need to make both your “Introduction” and Development of the Cardiovascular System” headings proper headings using the “==“ signs either side. This development section otherwise is very well laid out and comprehensible. I like your use of video and the way you have done a week-by-week breakdown.
The rest of your website is very well written and descriptive - I’m especially impressed by the detail in the development sections, and how you manage to convey the information clearly. It might be helpful to see a few images or figures showing the breakdown of this development to break up the text a little, but your subheadings are very helpful.
The CHARGE Syndrome section has a couple of issues with phrasing in the paragraph below the link, which you might wish to address.
The end of your website appears unfinished, for example in “human congenital heart diseases associated with Neural crest cells”; “research” and “animal models”, more detail and editing is required. You also have one referencing error which needs addressing. Overall, I am very impressed by your page.
The introduction is currently very brief, but this is probably one of the final parts of the webpage that you will address.
It would be good if you had a little bit of information on the history of the Dorsal Root Ganglion/neural crest discovery.
I find the second paragraph of Embryonic Origins a little confusing - it is unclear whether you are saying that the DRG cells are already differentiated before migration, or whether this happens after. This process is better explained/repeated a little in the next section on development process. Maybe the Embryonic origins section should be simplified to just describing the location of the original neural crest cells, if migration is mentioned later anyway.
In “Tissue Structure” there are a few errors in writing that require addressing. I like your drawn diagram - it complements the paragraph’s description well. The placement of the image is slightly off, but this can be adjusted in your final edits.
Your Molecular mechanisms/factors/genes section is very thorough and clearly described. A figure showing the flow of events in the signalling pathway might be helpful to go along with this.
You need to reference your abnormality section, and edit its format a little, as currently the image seems out of place.
The animal models section is really interesting and well written, but it needs referencing at the start.
I’m impressed with the “Current Research” section - it is well written and the image is interesting and complements the paragraph.
You have used a broad range of references for this site, which shows you have done some extensive research on your topic.
Neuropore cell shape changes
Physiology and Pathophysiology of Inner Ear Melanin
- Meyer zum Gottesberge AM. (1988). Physiology and pathophysiology of inner ear melanin. Pigment Cell Res. , 1, 238-49. PMID: 3070525