Template talk:Lung stage table

2019 Update

**Human Lung Stages**
Lung Stage	Human	Features	Vascular
Embryonic	week 4 to 5	lung buds originate as an outgrowth from the ventral wall of the foregut where lobar division occurs	extra pulmonary artery then lobular artery
Pseudoglandular	week 5 to 17	conducting epithelial tubes surrounded by thick mesenchyme are formed, extensive airway branching	Pre-acinar arteries
Canalicular	week 16 to 25	bronchioles are produced, increasing number of capillaries in close contact with cuboidal epithelium and the beginning of alveolar epithelium development	Intra-acinar arteries
Saccular	week 24 to 40	alveolar ducts and air sacs are developed	alveolar duct arteries
Alveolar	late fetal to 8 years	secondary septation occurs, marked increase of the number and size of capillaries and alveoli	alveolar capillaries
Links: Species Stage Comparison \| respiratory

**Human Lung Stages**
Stage	Human	Features
Embryonic	week 4 to 5	lung buds originate as an outgrowth from the ventral wall of the foregut where lobar division occurs
Pseudoglandular	week 5 to 17	conducting epithelial tubes surrounded by thick mesenchyme are formed, extensive airway branching
Canalicular	week 16 to 25	bronchioles are produced, increasing number of capillaries in close contact with cuboidal epithelium and the beginning of alveolar epithelium development
Saccular	week 24 to 40	alveolar ducts and air sacs are developed
Alveolar	late fetal to 8 years	secondary septation occurs, marked increase of the number and size of capillaries and alveoli
Links: Species Stage Comparison \| respiratory

Lung Development Species Comparison^[1]
Species	Term	Embryonic (days)	Pseudoglandular (days)	Canalicular (days)	Saccular (days)
Human	280	< 42	52 - 112	112 - 168	168
Primate	168	< 42	57 - 80	80 - 140	140
Sheep	150	< 40	40 - 80	80 - 120	120
Rabbit	32	< 18	21 - 24	24 - 27	27
Rat	22	< 13	16 - 19	19 - 20	21
Mouse	20	< 9	16	18	19

Lung Stages Species Comparison PMID 15774522

Stage	Human	Sheep	Features
Embryonic	week 4 to 5	day 0 to 40	lung buds originate as an outgrowth from the ventral wall of the foregut where lobar division occurs
Pseudoglandular	week 5 to 17	day 40 to 80	conducting epithelial tubes surrounded by thick mesenchyme are formed, extensive airway branching
Canalicular	week 16 to 25	day 80 to 120	bronchioles are produced, increasing number of capillaries in close contact with cuboidal epithelium and the beginning of alveolar epithelium development
Saccular	week 24 to 40	day 120 to 148	alveolar ducts and air sacs are developed
Alveolar	late fetal to 8 years		secondary septation occurs, marked increase of the number and size of capillaries and alveoli