Template:Papanicolaou1933 guinea pig and rat vaginal smear table

From Embryology
Vaginal Smear Comparison Table
Guinea pig Rat (Long and Evans)
I. Superficial squamous cells with pyknotic nuclei; progressive leucopenia. 1. Small round nucleated cells; disappearance of leucocytes.
Intermediate (cornification) period
a. Many cornified cells, usually mixed with type I cells;
b. Prevalence of cornified cells with cheesy masses; leucopenia
Cornification period
2. Early cornified cell stage; leucocytes scarce.
3. Late cornified cell stage with large cheesy masses; leucopenia
II, III, IV. Appearance of deep layer cells; reappearance and great exodus of leucocytes; gradual disappearance of cornifiecl cells; sometimes erythrocytes present. 4. Leucocytic-cornified cell stage; reappearance of leucocytes; gradual disappearance of the cornified cells.
V. Dioestrus: Leucocytes and atypical atypical vaginal cells. 5. Dioestrus: Leucocytes and vaginal cclls.
Reference: Papanicolaou GN. The Sexual Cycle in the Human Female as revealed by Vaginal Smears. Am J Anat. 1933;52: 519–637.
Links: Estrous Cycle | Guinea Pig Development | Rat Development