Template:Mouse Mammary Timeline table

From Embryology
Mouse Mammary Timeline
Day Event
E10 milk line first formed by a slight thickening and stratification of the surface ectoderm.
E10.5 expression of Wnt10b in mammary lines on the trunk between the limbs and in axillary and inguinal streaks.
E11.5 milk line breaks up into individual placodes and the underlying mammary mesenchyme begins to condense.
E15.5 mammary epithelium begins to proliferate at the tip and the primary sprout pushes through the mammary mesenchyme towards the underlying fat pad.
E18.5 elongating duct has now grown into the fat pad and has branched into a small ductal system. Cells of the mammary mesenchyme have formed the nipple, which is made of specialized epidermal cells.
Data source[1]   Related Images: E10/11 | E11 | E12 | E13 | E14.5
  1. Robinson GW. (2007). Cooperation of signalling pathways in embryonic mammary gland development. Nat. Rev. Genet. , 8, 963-72. PMID: 18007652 DOI.