Template:Mouse Human lung table
From Embryology
Stage | Human | Mouse | Features |
---|---|---|---|
Embryonic | week 4 to 5 | E9 to E11.5 | lung buds originate as an outgrowth from the ventral wall of the foregut where lobar division occurs |
Pseudoglandular | week 5 to 17 | E11.5 to E16.5 | conducting epithelial tubes surrounded by thick mesenchyme are formed, extensive airway branching |
Canalicular | week 16 to 25 | E16.5 to E17.5 | bronchioles are produced, increasing number of capillaries in close contact with cuboidal epithelium and the beginning of alveolar epithelium development |
Saccular | week 24 to 40 | E17.5 to PN5 | alveolar ducts and air sacs are developed |
Alveolar | late fetal to 8 years | PN5 to PN28 | secondary septation occurs, marked increase of the number and size of capillaries and alveoli |