Talk:Book - Sex and internal secretions (1961) 13

I. Introduction 707

II. Functional State of Gametes after Spermatogenesis 709

A. The Maturation of Spermatozoa . . 709

B. Cytogenetic Differences in Sperm 710

C. Requirements for Large Sperm Numbers 711

III. Sperm Transport and Storage in

the Male Tract 711

A. Sperm Transport 711

B. Sperm Survival 713

C. The Functional Microanatomy of the Epididymis 714

D. The Epididymis in Relation to Sperm Physiology 7](i

E. The Fate of the Nonutilized Sperm in the Male 720

F. Acquisition bv Sperm of the Capacity for Motility 721

IV. Insemination 722

A. Ejaculation 723

B. Collection of Seminal Components. 725

C. Seminal Volume and Successive Fractions 725

D. Effective Sperm Concentration. . . . 727

E. Site of Insemination 727

F. Artificial Insemination 727

V. Sperm Transport and Survival in THE Female Tr.\ct 729

A. Duration of Transport 729

B. Mechanism of Transport in the LTterus and Oviduct 731

C. Critical Regions of Sperm Transport 732

1. The cervix 734

2. The uterotubal junction 735

3. The isthmus 737

D. Number of Sperm at the Site of Fertilization 738

E. Duration of Fertilizing Capacity. . . 738

F. Duration of Sperm Motility throughout the Tract 740

G. Sperm Viability in Relation to Tubal Physiology 740

H. The Fate of Nonfertilizing Spermatozoa 744

VI. Imminologic Problems Assoct.a.ted wuru Spermatozoa 745

A. Antigenicity of Sperm 745

B. Sperm-induced Immune Responses in the Male 746

C. Sperm-induced Immune Responses in the Female 747

VII. Morphology and Composition of Spermatozoa 750

A. Structural Features 750

B. Biochemical Features 754

C. The Localization of Enzymes 755

D. The Sperm Surface 75(1

VIII. Sperm Metabolism 757

A. Sources of Energy 757

B. Invertebrate Sperm Metabolism. . . 758

C. Mammalian Sperm Metabolism. . . . 759

D. Epididymal Sperm and Metabolic Regulation 701

E. Human Sperm Metabolism 702

F. Metabolic-Thermodynamic Interrelations 764

G. Biosynthetic Activity 764

IX. Sperm Flagellation 7(55

A. Wave Patterns 765

B. Sperm Velocit}' 766

C. Hydrodynamics 766

D. Mechanism of Motility 767

X. Fertilizing Capacity of Treated Spermatozoa 769

A. Dilution of the Sperm Suspension. . 770

B. Temperature Effects 770

C. Ionizing Radiation 770

D. Ionic and Osmotic Effects 771

E. Effects of Biologic Fluids 772

XI. Conclusion 775

XII. References 775