Talk:BGDA Lecture - Development of the Nervous System

From Embryology

2019

Iodine deficiency  
Abnormal Development - Iodine Deficiency
 ICD-11

5B5K.3 Iodine deficiency - Iodine deficiency disorders (IDD), caused mainly by a low dietary supply of iodine, refer to all of the consequences of iodine deficiency in a population that can be prevented by ensuring that the population has an adequate intake of iodine. Iodine deficiency is the most frequent cause of preventable brain damage in childhood.

5A00.04 Congenital hypothyroidism due to iodine deficiency - Hypothyroidism is a condition which arises at birth where the thyroid gland produces too little or no thyroid hormone and it can be induced by iodine-deficiency.

2017

eMed URL Link: http://emed.med.unsw.edu.au/Map.nsf/wFrameset?OpenFrameSet&Frame=NotesView&Src=/Map.nsf/0/159748002E587E4ECA257339000628C9?OpenDocument&Login

Monday 29 May 2017 09:00 AM - 10:00 AM Development of the nervous system Kensington - Rex Vowels Theatre Hill, Mark


Neural groove closing to neural tube, early week 4
(Stage 10)
Brain size embryonic (week 4, 5, 6, and 8) and late fetal (third trimester)
Relative brain size embryonic (week 4, 5, 6, and 8) and late fetal (third trimester)


Neuropores

Cranial Neuropore Caudal Neuropore
Stage11 sem9.jpg Stage12 SEM3.jpg
(stage 11) (stage 12)
  • cranial (anterior) neuropore closes before caudal (posterior)
  • failure to close - Neural Tube Defects (NTD), severity dependent upon level, spina bifida anancephaly (More? [neuron2.htm Neural Abnormalities])
  • found that supplementation of maternal diet with folate reduces incidence of NTDs
    • A randomised controlled trial conducted by the Medical Research Council of the United Kingdom demonstrated a 72% reduction in risk of recurrence by periconceptional (ie before and after conception) folic acid supplementation (4mg daily).
    • Women who have one infant with a neural tube defect have a significantly increased risk of recurrence (40-50 per thousand compared with 2 per thousand for all births)


Early Brain Structure

Primary Vesicles Secondary Vesicles
CNS primary vesicles.jpg

Week 4 - rostral neural tube forms 3 primary brain vesicles

  1. prosencephalon (forebrain)
  2. mesencephalon (midbrain)
  3. rhombencephalon (hindbrain)
CNS secondary vesicles.jpg

Week 5 - 3 primary vesicles develop to form 5 secondary vesicles

  1. telencephalon (endbrain, forms cerebral hemispheres)
  2. diencephalon (between brain, forms optic outgrowth)
  3. mesencephalon (midbrain)
  4. metencephalon (behind brain)
  5. myelencephalon (medulla brain)

Textbook collapse table

Textbooks  

UNSW Embryology

Logo.png Hill, M.A. (2019). UNSW Embryology (19th ed.) Retrieved September 22, 2019, from https://embryology.med.unsw.edu.au
Neural Links: ectoderm | neural | neural crest | ventricular | sensory | Stage 22 | gliogenesis | neural fetal | Medicine Lecture - Neural | Lecture - Ectoderm | Lecture - Neural Crest | Lab - Early Neural | neural abnormalities | folic acid | iodine deficiency | Fetal Alcohol Syndrome | Postnatal | Postnatal - Neural Examination | Histology | Historic Neural | Category:Neural

The Developing Human: Clinically Oriented Embryology

Moore, K.L., Persaud, T.V.N. & Torchia, M.G. (2015). The developing human: clinically oriented embryology (10th ed.). Philadelphia: Saunders. (links only function with UNSW connection)

The Developing Human, 10th edn.jpg
The Developing Human: Clinically Oriented Embryology (10th edn) 
The Developing Human, 10th edn.jpg

UNSW Students have online access to the current 10th edn. through the UNSW Library subscription (with student Zpass log-in).


APA Citation: Moore, K.L., Persaud, T.V.N. & Torchia, M.G. (2015). The developing human: clinically oriented embryology (10th ed.). Philadelphia: Saunders.

Links: PermaLink | UNSW Embryology Textbooks | Embryology Textbooks | UNSW Library
  1. Introduction to the Developing Human
  2. First Week of Human Development
  3. Second Week of Human Development
  4. Third Week of Human Development
  5. Fourth to Eighth Weeks of Human Development
  6. Fetal Period
  7. Placenta and Fetal Membranes
  8. Body Cavities and Diaphragm
  9. Pharyngeal Apparatus, Face, and Neck
  10. Respiratory System
  11. Alimentary System
  12. Urogenital System
  13. Cardiovascular System
  14. Skeletal System
  15. Muscular System
  16. Development of Limbs
  17. Nervous System
  18. Development of Eyes and Ears
  19. Integumentary System
  20. Human Birth Defects
  21. Common Signaling Pathways Used During Development
  22. Appendix : Discussion of Clinically Oriented Problems

Larsen's Human Embryology

Schoenwolf, G.C., Bleyl, S.B., Brauer, P.R., Francis-West, P.H. & Philippa H. (2015). Larsen's human embryology (5th ed.). New York; Edinburgh: Churchill Livingstone.(links only function with UNSW connection)

Larsen's human embryology 5th ed.jpg
Larsen's Human Embryology (5th edn) 
Larsen's human embryology 5th ed.jpg
UNSW students have full access to this textbook edition through UNSW Library subscription (with student Zpass log-in).


APA Citation: Schoenwolf, G.C., Bleyl, S.B., Brauer, P.R., Francis-West, P.H. & Philippa H. (2015). Larsen's human embryology (5th ed.). New York; Edinburgh: Churchill Livingstone.

Links: PermaLink | UNSW Embryology Textbooks | Embryology Textbooks | UNSW Library
  1. Gametogenesis, Fertilization, and First Week
  2. Second Week: Becoming Bilaminar and Fully Implanting
  3. Third Week: Becoming Trilaminar and Establishing Body Axes
  4. Fourth Week: Forming the Embryo
  5. Principles and Mechanisms of Morphogenesis and Dysmorphogenesis
  6. Fetal Development and the Fetus as Patient
  7. Development of the Skin and Its Derivatives
  8. Development of the Musculoskeletal System
  9. Development of the Central Nervous System
  10. Development of the Peripheral Nervous System
  11. Development of the Respiratory System and Body Cavities
  12. Development of the Heart
  13. Development of the Vasculature
  14. Development of the Gastrointestinal Tract
  15. Development of the Urinary System
  16. Development of the Reproductive System
  17. Development of the Pharyngeal Apparatus and Face
  18. Development of the Ears
  19. Development of the Eyes
  20. Development of the Limbs

More Textbooks?