Talk:2009 Lecture 9

Background Reading

• http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2009;volume=52;issue=4;spage=461;epage=472;aulast=Sharma

signaling

• Hedgehog - Paracrine Hedgehog signaling in stomach and intestine: new roles for hedgehog in gastrointestinal patterning. Kolterud A, Grosse AS, Zacharias WJ, Walton KD, Kretovich KE, Madison BB, Waghray M, Ferris JE, Hu C, Merchant JL, Dlugosz AA, Kottmann AH, Gumucio DL. Gastroenterology. 2009 Aug;137(2):618-28. PMID: 19445942

• Sonic hedgehog and bone morphogenetic protein-4 signaling pathway involved in epithelial cell renewal along the radial axis of the intestine.

Ishizuya-Oka A, Hasebe T. Digestion. 2008;77 Suppl 1:42-7. Epub 2008 Jan 18. Review. PMID: 18204261

• Wnt - Phases of canonical Wnt signaling during the development of mouse intestinal epithelium. Kim BM, Mao J, Taketo MM, Shivdasani RA. Gastroenterology. 2007 Aug;133(2):529-38. PMID: 17681174

• Bone morphogenetic proteins. Chen D, Zhao M, Mundy GR. Growth Factors. 2004 Dec;22(4):233-41. Review. PMID: 15621726

pylorus

• Dynamic patterning at the pylorus: Formation of an epithelial intestine-stomach boundary in late fetal life. Li X, Udager AM, Hu C, Qiao XT, Richards N, Gumucio DL. Dev Dyn. 2009 Oct 29. PMID: 19877272
• Villin: A marker for development of the epithelial pyloric border. Braunstein EM, Qiao XT, Madison B, Pinson K, Dunbar L, Gumucio DL. Dev Dyn. 2002 May;224(1):90-102. PMID: 11984877

Take the Quiz

1 Both blood stem cells and the endothelial lining of blood vessels arise from blood islands.

	true
	false

2 The region of the early heart tube that corresponds to the inflow and out flow respectively are:

	inferior vena cava and aortic arch
	portal artery and aorta
	sinus arteriosus and cordus bulbus
	truncus arteriosus and sinus venosus

3 Embryonic red blood cells only differ from adult cells in still having nuclei.

	true
	false

4 The embryo cardinal venous vessels which drain into the sinus venosus are:

	anterior cardinal veins
	common cardinal veins
	inferior cardinal veins
	superior cardinal veins

5 The embryonic heart rate rises throughout development.

	true
	false