Paper - On a normal ovum of approximately 9 to 10 days of age
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Hertig AT. and Rock J. On a normal ovum of approximately 9 to 10 days of age. (1945) Anat. Rec, 91: 281.
Hertig AT. and Rock J. On a human blastula recovered from the uterine cavity 4 days after ovulation. (1946) J Gerontol. 1(1): 96-117.
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On a Normal Ovum of Approximately 9 to 10 days of Age
Free Hospital for Women, Brookline, Mass., Departments of Pathology, Obstetrics and Gynecology, Harvard Medical School and Department of Embryology, Carnegie Institution of Washington.
Abstract from the 1945 annual meeting of American Association of Anatomists
The ovum (Carnegie Embryo 8215) was discovered in a uterus removed surgically on the fifty-sixth day of the menstrual cycle (periodicity infrequent and irregular). Endometrial histology indicated a typical twenty-fourth day secretory phase with ovulation having occurred approximately 10 days before. The implantation site was posterior, at the corm opposite the ovary of origin, and without visible vascular response. It appeared as a slight elevated area measuring 0.57 mm. in diameter surmounted by a tiny 0.115 X 0.154 mm. area of ulceration.
The chorion measures 0.207 X 0.498 X 0.525 mm.; the chorionic cavity 0.100 X 0.210 X 0.228 mm.; the embryo 0.050 X 0.052 X 0.084 mm. and the amniotic cavity 0.022 X 0.048 X 0.050 mm. The ovum is nearly completely embedded within a rather markedly vascular but relatively ischemic endometrium showing only minimal predecidual response. The trophoblast, indifferent at the abembryonic pole, possesses elsewhere an inner cytotrophoblast and an outer, lacuna-riddled, blood-filled syncytiotrophoblast.
The nearly globular, normally situated, bilaminar germ disk shows early vacuolization of its ectoderm. The amnion is well formed but still lightly attached to its parental trophoblast. Mesoblast formation is active with development of the exocoelomic (Heuser’s) membrane. Angiogenesis is absent within the chorionic cavity. Focal accumulations of cytotrophoblast - primordia of chorionic villi - are beginning to appear.
Cite this page: Hill, M.A. (2019, April 19) Embryology Paper - On a normal ovum of approximately 9 to 10 days of age. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Paper_-_On_a_normal_ovum_of_approximately_9_to_10_days_of_age
- © Dr Mark Hill 2019, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G