|Embryology - 7 Dec 2019 Expand to Translate|
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The domestic sheep (Ovis aries) has been used as a mammalian model of development with a term gestational period of 145 - 150 days.
|Animal Development Time|
|Animal Notes and Table Data Sources
Some Recent Findings
|More recent papers|
This table allows an automated computer search of the external PubMed database using the listed "Search term" text link.
Search term: Sheep Embryology
<pubmed limit=5>Sheep Embryology</pubmed>
- day 4 - embryo enters the uterus at the morula stage of development
- day 6 - develops into a blastocyst
- day 8 - blastocyst hatches from zona pellucida
- day 11-16 - elongates to a filamentous form
- day 14 - 16 - binucleate cells begin to differentiate in the trophoblast
- day 16 - adplantation
See also Implantation mechanisms: insights from the sheep
A female domestic sheep remarkable in being the first mammal to be cloned from an adult somatic cell, using the process of nuclear transfer.
Cloned by Ian Wilmut, Keith Campbell and colleagues at the Roslin Institute near Edinburgh in Scotland, born on 5 July 1996 and she lived until the age of six (5 July 1996 – 14 February 2003). The cell used as the donor for the cloning of Dolly was taken from a mammary gland, and the production of a healthy clone therefore proved that a cell taken from a specific part of the body could recreate a whole individual. As Dolly was cloned from part of a mammary gland, she was named after the famously curvaceous country western singer Dolly Parton.
|Sheep follicle gene expression||
Sheep Oocyte Distribution of Telomerase reverse transcriptase
The following oocyte images are from a recent study of sheep in vitro follicle development.
|early antral||preovulatory follicle|
- TERT - Red (Cy3-conjugated secondary antibody) (telomerase reverse transcriptase, TERT)
- DNA - Green (SYBR Green 14/I)
- Sheep Oocyte TERT: preantral | early antral | early antral | preovulatory follicle | Oocyte Development | Sheep Development
Phases of fetal lung development:
- embryonic - 0 to 40 days.
- pseudoglandular - 40 to 80 days.
- canalicular - 80 to 120 days.
- saccular - 120 to term 148 days gestation.
- Links: Respiratory Development
Lymphocytes development has been characterised by an immunohistology study of T lymphocytes in the sheep fetal spleen.
- 43-44 days of gestation, SBU-T1- and SBU-T8-positive lymphocytes were present in low numbers.
- 45-50 days of gestation Surface immunoglobulin (sIg) was first detected on fetal spleen cells
- 50-55 days of gestation SBU-T4, 20.96-, 25.69-, 38.38-, or 46.66-positive lymphocytes present.
- 57 days of gestation SBU-T19 lymphocytes appeared.
- Links: Immune Development
- <pubmed>22132111</pubmed>| PLoS One.
- <pubmed>26540452</pubmed>| PLoS One.
- <pubmed>22132111</pubmed>| PLoS One.
- <pubmed>15774522</pubmed>| PMC1464504
<pubmed>19909921</pubmed> <pubmed>15047940</pubmed>| Reproduction
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Cite this page: Hill, M.A. (2019, December 7) Embryology Sheep Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Sheep_Development
- © Dr Mark Hill 2019, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G