File:Ovarian follicular steroid synthesis.jpg
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Ovarian follicular steroid synthesis
Diagramatic representation of the steroidogenic pathways in human pre-luteinized follicles (A) and post luteinized follicles (B), demonstrating granulosa dependence on theca cell testosterone steroidogenesis in pre-luteinized follicles and the de novo synthesis of progesterone from cholesterol due to induction/up-regulation of CYP11A and 3βHSD after the gonadotropin surge in post luteinized follicles.
The principle steroid product of luteinized pre-ovulatory granulosa is progesterone, a differentiation triggered by the gonadotropin surge. However, absolute steroid levels are associated with follicular size, not oocyte maturation/ability to fertilize.
Reference
<pubmed>20937107</pubmed>| Reprod Biol Endocrinol.
Wen et al. Reproductive Biology and Endocrinology 2010 8:117 doi:10.1186/1477-7827-8-117
Copyright
© 2010 Wen et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Original file name: Figure 5. 1477-7827-8-117-5-l.jpg
Cite this page: Hill, M.A. (2024, April 23) Embryology Ovarian follicular steroid synthesis.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Ovarian_follicular_steroid_synthesis.jpg
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G
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| current | 15:35, 17 May 2011 | | 1,200 × 645 (89 KB) | S8600021 (talk | contribs) | ==Ovarian follicular steroid synthesis== Diagramatic representation of the steroidogenic pathways in human pre-luteinized follicles (A) and post luteinized follicles (B), demonstrating granulosa dependence on theca cell testosterone steroidogenesis in pr |
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