File:Organoids overview 01.jpg
Original file (685 × 776 pixels, file size: 146 KB, MIME type: image/jpeg)
Organoid establishment from stem cells and cancer cells
Embryonic stem cells from human embryonic tissues and induced pluripotent stem cells from adult tissues firstly experience directed differentiation, generate floating spheroids, and subsequently are planted on extracellular matrix in specific culture medium to initiate organoid culture.
Primary tissues from patients can be dissociated into functional units, which contain somatic stem cells. These somatic stem cells are enriched and cultured in three-dimensional medium to form organoids. Tumor cells isolated from cancer tissues can also form tumoroids in well-defined three-dimensional culture.
- Links: organoids
Reference
Xu H, Lyu X, Yi M, Zhao W, Song Y & Wu K. (2018). Organoid technology and applications in cancer research. J Hematol Oncol , 11, 116. PMID: 30219074 DOI.
Copyright
Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
13045_2018_662_Fig1_HTML.jpg
Cite this page: Hill, M.A. (2024, March 19) Embryology Organoids overview 01.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Organoids_overview_01.jpg
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G
File history
Click on a date/time to view the file as it appeared at that time.
Date/Time | Thumbnail | Dimensions | User | Comment | |
---|---|---|---|---|---|
current | 06:59, 30 July 2019 | 685 × 776 (146 KB) | Z8600021 (talk | contribs) | Organoid establishment from stem cells and cancer cells. Embryonic stem cells from human embryonic tissues and induced pluripotent stem cells from adult tissues firstly experience directed differentiation, generate floating spheroids, and subsequently... |
You cannot overwrite this file.