File:Neural crest cell enteric sorting.jpg
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Neural crest cell enteric sorting
Scheme of ENS neuron (red) and ENC (blue) aggregation.
A. Initially ENC cells and neurons cohere in a disorderly fashion (2–4 h) but gradually the neurons sort out to a central position (18 h), indicating neurons have a greater adhesive bond energy.
B. Neurons and ENC cells have adhesive molecules (coloured circles) which are free to move in the cell surface, but the neurons have more adhesive molecules. Cell-cell adhesion requires juxtaposition in trans of two adhesive molecules (red-red, blue-blue or red-blue). To minimise adhesive free energy, adhesive molecules on ENC cells move (pink arrows) in order to form an adhesion, thereby denuding the outer face of adhesion molecules. This insulates the group from further adhesion.
Reference
<pubmed>26064478 </pubmed>
Benjamin N. Rollo, et al. F1000Res. 2015;4:113.
Copyright
© 2015 Rollo BN et al. This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Data associated with the article are available under the terms of the Creative Commons Zero "No rights reserved" data waiver (CC0 1.0 Public domain dedication).
Figure 10.
Cite this page: Hill, M.A. (2024, April 19) Embryology Neural crest cell enteric sorting.jpg. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/File:Neural_crest_cell_enteric_sorting.jpg
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 13:50, 3 September 2017 | | 800 × 849 (61 KB) | Z8600021 (talk | contribs) | Figure 10. Scheme of ENS neuron (red) and ENC (blue) aggregation.. From: Why are enteric ganglia so small? Role of differential adhesion of enteric neurons and enteric neural crest cells.. A. Initially ENC cells and neurons cohere in a disorderly fashi... |
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